Fluconazole In Sodium Chloride Injection while Breastfeeding
Do you know that important immune protective proteins are present in breast milk? Breast milk also contains required vitamins, minerals, saturated and un saturated fats. These things are extremely important for development of healthy brain. If you are taking any medicine for short term or for the chronic reason then that passes in breast milk as well, that is why you should always check the drug with your health care provider. Here at DrLact we try to analyze drugs based on available researches and in this sheet we will present our analysis for Fluconazole In Sodium Chloride Injection.

What is Fluconazole In Sodium Chloride Injection used for?


Fluconazole is indicated for the treatment of: Oropharyngeal and esophageal candidiasis. In open noncomparative studies of relatively small numbers of patients, fluconazole was also effective for the treatment of Candida urinary tract infections, peritonitis, and systemic Candida infections including candidemia, disseminated candidiasis, and pneumonia. Cryptococcal meningitis. Before prescribing fluconazole for AIDS patients with cryptococcal meningitis, please see CLINICAL STUDIES section. Studies comparing fluconazole to amphotericin B in non-HIV infected patients have not been conducted. Prophylaxis Fluconazole is also indicated to decrease the incidence of candidiasis in patients undergoing bone marrow transplantation who receive cytotoxic chemotherapy and/or radiation therapy. Specimens for fungal culture and other relevant laboratory studies (serology, histopathology) should be obtained prior to therapy to isolate and identify causative organisms. Therapy may be instituted before the results of the cultures and other laboratory studies are known; however, once these results become available, anti-infective therapy should be adjusted accordingly.

What are the risk associated with Fluconazole In Sodium Chloride Injection usage while breastfeeding? What precautions shall I take while using it in breastfeeding?

Fluconazole In Sodium Chloride Injection safe for breastfeeding
Active ingredient in Fluconazole In Sodium Chloride Injection is Fluconazole and based on our analysis of Fluconazole it appears that using Fluconazole In Sodium Chloride Injection is safe in breastfeeding. Below is analysis of Fluconazole while breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers Fluconazole was present in low levels in breast milk following administration of a single 150 mg dose, based on data from a study in 10 breastfeeding women who temporarily or permanently discontinued breastfeeding 5 days to 19 months postpartum. The estimated daily infant dose of fluconazole from breast milk (assuming mean milk consumption of 150 mL/kg/day) based on the mean peak milk concentration (2.61 mcg/mL [range: 1.57 to 3.65 mcg/mL] at 5.2 hours post-dose) was 0.39 mg/kg/day, which is approximately 13% of the recommended pediatric dose for oropharyngeal candidiasis. (Labeled pediatric dose is 6 mg/kg/day on the first day followed by 3 mg/kg/day; estimated infant dose is 13% of 3 mg/kg/day maintenance dose). There are no data on fluconazole levels in milk after repeated use or after high-dose fluconazole. A published survey of 96 breastfeeding women who were treated with fluconazole 150 mg every other day (average of 7.3 capsules [range 1 to 29 capsules]) for lactation-associated candida of the breasts reported no serious adverse reactions in infants. Caution should be exercised when fluconazole is administered to a nursing woman.

Fluconazole In Sodium Chloride Injection Breastfeeding Analsys


Fluconazole while Breastfeeding

Safe

CAS Number: 86386-73-4

Excreted into breast milk in much lesser amount than that used for the treatment of Candida infection in the infant. Problems have not appeared in breastfed infants from treated mothers. Widely used for the treatment of breast pain due or allegedly due to Candida infection. In those cases of breast candidiasis where topical treatment fails, oral Fluconazole may be used at a dose of 200 mg for the first day to be followed by 100 mg daily for two weeks. The American Academy of Pediatrics rates it compatible with breastfeeding.

Fluconazole In Sodium Chloride Injection Breastfeeding Analsys - 2


Fluconazole while Breastfeeding

CAS Number: 86386-73-4

Fluconazole is acceptable in nursing mothers because amounts excreted into breastmilk are less than the neonatal fluconazole dosage.[1] Although no adequate clinical studies on fluconazole in mastitis have been published, a survey of members of the Academy of Breastfeeding Medicine found that fluconazole is often prescribed for nursing mothers to treat breast candidiasis, especially with recurrent or persistent infections.[2] Treatment of the mother and infant simultaneously with fluconazole is often used when other treatments fail.[2][3][4][5] The most common maternal dosage regimen is 400 mg once, followed by 200 mg daily for at least 2 weeks or until pain is resolved,[6][7] although a study in Australia used a dose of 150 mg every other day until breast pain resolved.[8] The dosage of fluconazole in breastmilk with these maternal dosages is not sufficient to treat oral thrush in the infant.

Fluconazole In Sodium Chloride Injection and breastfeeding

I already used Fluconazole In Sodium Chloride Injection and meanwhile I breastfed my baby should I be concerned?

Fluconazole In Sodium Chloride Injection is safe in breastfeeding and should not create any health problem for your baby but in case you feel any health issue associated with Fluconazole In Sodium Chloride Injection you should contact your doctor or health care provider. Be it pregnancy or lactation you shall keep your doctor informed.


I am nursing mother and my doctor has suggested me to use Fluconazole In Sodium Chloride Injection, is it safe?

Usage of Fluconazole In Sodium Chloride Injection is safe for nursing mothers and baby, No worries.


If I am using Fluconazole In Sodium Chloride Injection, will my baby need extra monitoring?

No


Who can I talk to if I have questions about usage of Fluconazole In Sodium Chloride Injection in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week