Neomycin Polymyxin B Sulfates And Dexamethasone | Neomycin Sulfate 3.5 Mg, Polymyxin B Sulfate 10000 [usp'u], Dexamethasone 1 Mg while Breastfeeding
American Academy of Pediatrics and other medical experts exclusively recommend to breastfeed the baby for first 6 months. Once you introduce baby to other foods it is recommended to breastfeed for at least first year of babys life. Taking medication while breastfeeding could be tricky as most drugs pass in breast milk. In this article we will evaluate Neomycin Polymyxin B Sulfates And Dexamethasone | Neomycin Sulfate 3.5 Mg, Polymyxin B Sulfate 10000 [usp'u], Dexamethasone 1 Mg for its safety in breastfeeding.

What is Neomycin Polymyxin B Sulfates And Dexamethasone | Neomycin Sulfate 3.5 Mg, Polymyxin B Sulfate 10000 [usp'u], Dexamethasone 1 Mg ?


: For steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where bacterial infection or a risk of bacterial ocular infection exists. Ocular steroids are indicated in inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe where the inherent risk of steroid use in certain infective conjunctivitis is accepted to obtain a diminution in edema and inflammation. They are also indicated in chronic anterior uveitis and corneal injury from chemical, radiation or thermal burns, or penetration of foreign bodies. The use of a combination drug with an anti-infective component is indicated where the risk of infection is high or where there is an expectation that potentially dangerous numbers of bacteria will be present in the eye. The particular anti-infective drug in this product is active against the following common bacterial eye pathogens: Staphylococcus aureus, Escherichia coli, Haemophilus influenzae, Klebsiella/Enterobacter species, Neisseria species, Pseudomonas aeruginosa. This product does not provide adequate coverage against Serratia marcescens, and Streptococci, including Streptococcus pneumoniae.

Neomycin Polymyxin B Sulfates And Dexamethasone | Neomycin Sulfate 3.5 Mg, Polymyxin B Sulfate 10000 [usp'u], Dexamethasone 1 Mg safe in breastfeeding?

Neomycin Polymyxin B Sulfates And Dexamethasone | Neomycin Sulfate 3.5 Mg, Polymyxin B Sulfate 10000 [usp'u], Dexamethasone 1 Mg low risk for breastfeeding
Task to evaluate the effect of Neomycin Polymyxin B Sulfates And Dexamethasone | Neomycin Sulfate 3.5 Mg, Polymyxin B Sulfate 10000 [usp'u], Dexamethasone 1 Mg is quite difficult as it consist mainly 3 ingredients. However we have analyzed all 3 active ingredients and have reached a conclusion that Neomycin Polymyxin B Sulfates And Dexamethasone | Neomycin Sulfate 3.5 Mg, Polymyxin B Sulfate 10000 [usp'u], Dexamethasone 1 Mg poses low risk while breastfeeding. Below we have summarized our analysis of each 3 ingredients.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers Systemically administered corticosteroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects. It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in human milk. Because many drugs are excreted in human milk, caution should be exercised when neomycin and polymyxin B sulfates and dexamethasone ophthalmic suspension is administered to a nursing woman.

Neomycin Polymyxin B Sulfates And Dexamethasone | Neomycin Sulfate 3.5 Mg, Polymyxin B Sulfate 10000 [usp'u], Dexamethasone 1 Mg Breastfeeding Analsys


Neomycin sulfate while Breastfeeding

Safe

CAS Number: 1404-04-2

Aminoglycoside antibiotic which is used in creams, eye drops, and otologic preparations for topical use, and, also orally used for intestinal disinfection. At latest update, relevant published data on excretion in the breast milk were not found. Like other aminoglycoside antibiotics, Neomycin is not absorbed by the gut. Absorption from other sources like skin, nose, ear and eye mucosa by means of topically used preparations (creams, drops, etc.) is very poor which causes excretion into breast milk in significant amount, unlikely. Do not apply creams, gels and other products that would contain paraffin (mineral oil) to avoid absorption by the infant since it is a hydrocarbon-derived substance. In case of use of Neomycin on the nipple, let it be done after the feed and wipe it out any excess of cream before the next feed. Be aware of false negative results of microbial cultures done from samples of febrile infants whose mothers are treated with antibiotics. Also, due to imbalance of intestinal flora a diarrheal disease can occur in the breastfed infant. List of Essential Medicines by WHO 2002: compatible with breastfeeding.

Polymyxin b sulfate while Breastfeeding

Safe

CAS Number: 1405-20-5

Antibiotic drug that is usual topically used (Dermatology, ENT and Ophthalmology) At latest update no published data on excretion into breast milk were found. The small dose and low absorption to the plasma in a majority of preparations that are topically used on the eye, ear or skin make a significant excretion into the milk unlikely. Its high molecular weight makes less probable an excretion into breast milk in significant amount. Due to a poor oral bioavailability, appearance in the infant's plasma from ingested milk is regarded as nil or scanty, except in premature infants or during the immediate neonatal period who may show an increased intestinal absorption. Polymyxin E or Colistin with a very similar molecular structure is excreted into breast milk in non-significant amount. It is advisable to avoid the application of creams, gels and other products for local use that would contain paraffin (mineral oil) to prevent absorption by the infant.

Dexamethasone while Breastfeeding

Low Risk

CAS Number: 50-02-2

Pharmacokinetic data indicate that excretion into breast milk in significant levels is possible, hence for long term treatments other steroids with lower excretion would be advisable. Other steroids (Betamethasone) that are administered prior to delivery can produce a delay of Lactogenesis phase II (milk's coming in) and a decrease of milk production within the first post-partum week. Intra-articular injected large doses of other steroids (Triamcinolone, Methylprednisolone) may transiently affect milk production. A decrease of prolactin release after administration of dexamethasone has been observed that may decrease milk production mostly in the first post-partum weeks. Topical use: Because of a low absorption through skin significant excretion into breast milk is unlikely. Additionally, a high protein binding makes excretion even more unlikely. Whenever a treatment for nipple eczema or dermatitis is required the lowest potency steroid compound should be used. It should be applied right after the feed to make sure it has disappeared before the next nursing occurs. Otherwise, wipe cream out with a clean gauze. Do not continuously use for longer than a week. Reportedly, a case of mineral-steroid toxicity has occurred due to continuous use of cream on the nipple. Creams, gels or similar products that contain paraffin or mineral oil should not be used on the nipple to avoid absorption by the infant. Corticoids are frequently prescribed in Pediatrics with no side effects on the infant when indicated for short-term or sporadical use. On nursing mothers a timely use or not long-term treatment is compatible with breastfeeding along with the assessment of milk production. WHO Model List of Essential Drugs 2002: Compatible with breastfeeding in single dose. No data is available on long-term use.


Neomycin Polymyxin B Sulfates And Dexamethasone | Neomycin Sulfate 3.5 Mg, Polymyxin B Sulfate 10000 [usp'u], Dexamethasone 1 Mg Breastfeeding Analsys - 2


Neomycin sulfate while Breastfeeding

CAS Number: 1404-04-2

Although no information exists on the excretion of neomycin into milk, other aminoglycoside antibiotics are poorly excreted into breastmilk. Newborn infants apparently absorb small amounts of aminoglycosides, but serum levels are far below those attained when treating newborn infections and systemic effects of neomycin are unlikely. Older infants would be expected to absorb even less neomycin. Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (e.g., thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis. Oral, topical, ophthalmic or otic neomycin should result in very low levels in breastmilk and present negligible risk to the infant,[1][2] although topical application to the nipple may increase the risk of diarrhea in the infant. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[3]

Polymyxin b sulfate while Breastfeeding

CAS Number: 1404-26-8

Because it is poorly absorbed after topical application, polymyxin B is considered a low risk to the nursing infant.[1] Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]

Dexamethasone while Breastfeeding

CAS Number: 50-02-2

Because no information is available on the use of systemic dexamethasone during breastfeeding, an alternate corticosteroid may be preferred, especially while nursing a newborn or preterm infant. Local injections, such as for tendinitis, would not be expected to cause any adverse effects in breastfed infants, but might occasionally cause temporary loss of milk supply.



I already used Neomycin Polymyxin B Sulfates And Dexamethasone | Neomycin Sulfate 3.5 Mg, Polymyxin B Sulfate 10000 [usp'u], Dexamethasone 1 Mg and meanwhile I breastfed my baby should I be concerned?

During whole lactation period you shall first discuss with your doctor and then together you shall decide whether you shall take that drug or not however if you have already taken Neomycin Polymyxin B Sulfates And Dexamethasone | Neomycin Sulfate 3.5 Mg, Polymyxin B Sulfate 10000 [usp'u], Dexamethasone 1 Mg then you shall inform your doctor, But you should not be worried too much as Neomycin Polymyxin B Sulfates And Dexamethasone | Neomycin Sulfate 3.5 Mg, Polymyxin B Sulfate 10000 [usp'u], Dexamethasone 1 Mg comes in category of low risk drug.


My doctor has prescribed me Neomycin Polymyxin B Sulfates And Dexamethasone | Neomycin Sulfate 3.5 Mg, Polymyxin B Sulfate 10000 [usp'u], Dexamethasone 1 Mg, what should I do?

Though Neomycin Polymyxin B Sulfates And Dexamethasone | Neomycin Sulfate 3.5 Mg, Polymyxin B Sulfate 10000 [usp'u], Dexamethasone 1 Mg dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.


If I am using Neomycin Polymyxin B Sulfates And Dexamethasone | Neomycin Sulfate 3.5 Mg, Polymyxin B Sulfate 10000 [usp'u], Dexamethasone 1 Mg, will my baby need extra monitoring?

Not much


Who can I talk to if I have questions about usage of Neomycin Polymyxin B Sulfates And Dexamethasone | Neomycin Sulfate 3.5 Mg, Polymyxin B Sulfate 10000 [usp'u], Dexamethasone 1 Mg in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week