Used in the treatment of promyelocitic leukemia in adults.
CAS Number: 8012-96-2
The use of dried extract at normalized dilutions is indicated to induce vomiting; for those cases of intoxication among lactating mothers, who do not have clinical contraindications to induce emesis, it is considered to be safe by WHO.
CAS Number: 7778-50-9
Así como el Cromo (véase ficha) en estado trivalente (3+) y a dosis apropiadas carece de toxicidad y constituye un oligoelemento nutricional esencial, las sales hexavalentes (6+) de cromo tienen usos industriales (cromado), son oxidantes, corrosivas, irritantes, están catalogadas como carcinogenos 1A y mutágenos 1B (INSHT 2012, ATSDR 2012), pueden causar dermatitis de contacto y toxicidad crónica y aguda grave.El cromo 6+ se encuentra también en el humo de combustión del tabaco, en cosméticos (Hepp 2014) y en algunas prótesis osteoarticulares (Oppermann 2015). Los compuestos de cromo exavalente, por su peligrosidad, no tienen actualmente usos médicos. A nivel de riesgo laboral para la madre lactante, las frases (INSHT 2008) de riesgo (antiguas frases R, actualmente frases H de Hazard, peligro) o de prudencia (frases P) que deben aparecer en la ficha de seguridad de un producto son sólo dos:- H362 (ant. R64): "Puede perjudicar a los niños alimentados con leche materna"- P263: "Evitar el contacto durante el embarazo y la lactancia"Otras tres frases que se deben considerar durante la lactancia tienen relación con el poder cancerígeno, mutagénico o acumulativo de un producto:- H351 (ant. R40): "Posibles efectos cancerígenos" - H371 (ant. R68): "Posibilidad de efectos irreversibles" - H373 (ant. R33): "Peligro de efectos acumulativos" Basándose en la ausencia de estas frases en las fichas de seguridad del trióxido de cromo (Panreac 2012, INSHT 2005), no sería preciso apartar a la madre lactante de su puesto de trabajo, bastándole a la empresa con cumplir las exigencias legales de valores máximos de exposición ambiental y a la trabajadora las normas aconsejadas de prudencia (guantes, lavado de manos, cambio de ropa, etc. (Panreac 2012). Pero según la normativa europea vigente (Reglamento CE 2008) cuando un producto es carcinógeno y mutágeno, las madres lactantes trabajadoras no deben estar expuestas a mezclas, sean de sólidos, líquidos o gases, con límites de concentración superiores a 0,3%.Además resulta un anomalía el que estando clasificado como cancerígeno 1A, no se le aplique la frase H351 (R40). A la luz de toda la bibliografía, consideramos que la madre lactante no debería estar expuesta a compuestos hexavalentes de cromo en el ambiente laboral.
CAS Number: 8007-93-0
In herbal medicine the leaves of this plant that contains numerous alkaloids are used: l-hyoscyamine and atropine, scopolamine or hyoscine and, all of them potentially high toxic.Traditionally used with poor clinical evidence based on trials as anti-asthmatic, for common colds and intestinal spasms. At latest update no published data on excretion into breast milk were found. With anticholinergic and antimuscarinic properties that may reduce milk production: if necessary take as low dose as possible and avoid long-term treatment if decreasing milk production is observed.Serious side effects (tachycardia, thirst, fever, mydriasis, seizures, coma), especially in infants and newborns (Caksen 2003 Laffargue 2011, Glatstein 2014, Rodríguez-González 2014).There have been cases of gangrene when applied to the chest (Wani 2011). Belladonna may be included in association with other “over the counter" medications of doubtful effectiveness or safety. Overall drug associations are not recommended. Cautions when taking herbal teas:1. Make sure it is obtained from a reliable source: reportedly, poisonings have occurred due to confusion after using another plant with toxic effects (Hsu 1995), some others contain heavy metals that may cause poisoning and others may cause food poisoning due to contamination with bacteria or fungi.2. Do not take it excessively. "Natural" products are not always good in any amount: plants contain active substances from which are made many compounds of our traditional pharmacopoeia that can cause poisoning if consumed in exaggerated quantities or for long periods.
CAS Number: 7439-97-6
Environmental pollutant that is used for manufacturation of batteries, fungicidal products, dental amalgam, and contaminated fish. Most of mercury present in breast milk does it as an inorganic substance which is almost non-absorbable. Breastfeeding should be discontinued whenever a mother is contaminated or intoxicated. It may be a source of neurological troubles. Benefits of breastfeeding are largely more important than risk related to the presence of mild level environment pollutants in human milk, in many instances, they are at lower content than those found in cow’s milk or other foods. (Codex alimentarius FAO-WHO).
CAS Number: 1327-53-3
Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy. It might be possible to breastfeed safely during intermittent therapy with an appropriate period of breastfeeding abstinence; the manufacturer recommends an abstinence period of 1 week after the last dose. Chemotherapy may adversely affect the normal microbiome and chemical makeup of breastmilk. Women who receive chemotherapy during pregnancy are more likely to have difficulty nursing their infant.
CAS Number: 8007-93-0
Belladonna (Atropa belladonna) contains anticholinergic alkaloids such as atropine and scopolamine. Belladonna has been used in the past for headache, airway obstruction, and irritable bowel syndrome among others, but its use has been supplanted by more specific and less toxic compounds. Long-term use of belladonna might reduce milk production by reducing serum prolactin. Application of belladonna paste to the nipple to reduce milk secretion during lactation is an extremely old use. However, it is still used this way in rural India for treating breast abscesses and may have contributed to cases of breast gangrene. Because of the narrow therapeutic index and variable potency of plant-based (i.e., nonstandardized) belladonna, it should be avoided orally and topically during lactation. Homeopathic products are not likely to interfere with breastfeeding or cause toxicity. Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information #about dietary supplements# is available elsewhere on the LactMed Web site.
Pulsatilla (Anemone pulsatilla and other related species) contains ranunculin, protoanemonin, and anemonin as well as triterpene saponins and flavonoids. The fresh plant is extremely irritating to the skin, gastrointestinal tract and mucous membranes. Allergic reactions have been reported to pulsatilla. Homeopathic preparations of pulsatilla are reportedly used for sore nipples and mastitis, to reduce an overabundant milk supply, or to increase milk supply. Galactogogues should never replace evaluation and counseling on modifiable factors that affect milk production. No scientifically valid clinical trials support either of these uses. Because of a lack of information, other agents may be preferred in nursing mothers. Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed
Due to high dilution of ingredients in homeopathic medicines they do not create much problem for baby. Cough And Cold Relief | Drosera Rotundifolia, Arsenicum Album, Ipecacuanha, Kali Bichromicum, Belladonna, Pulsatilla, Mercurius Solubilis Liquid is a homeopathic medicine and if your baby does not have any abnormal symptoms then there is nothing to worry about. Be careful with too much usage of ethanol based homeopathic medicines during breastfeeding.
Homeopathic medicines are usually safe in breastfeeding and if Cough And Cold Relief | Drosera Rotundifolia, Arsenicum Album, Ipecacuanha, Kali Bichromicum, Belladonna, Pulsatilla, Mercurius Solubilis Liquid has been recommended by doctor then there should be no concern about its usage in breastfeeding.
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