Phoxillum Bk4/2.5 Breastfeeding
Most health expert recommend six month of exclusive breastfeeding but statics suggest that numbers are not good, almost 95% mothers start breastfeeding but this number drops to 40% in first three month and further it drops to 15% till fifth month. Sometime its due to need of medication usage. Because of these statics its important to provide good information on safety of drugs in breastfeeding so that it can be improved when possible. In this FAQ sheet we will discuss about exposure to Phoxillum Bk4/2.5 while breastfeeding. We will also discuss about common side effects and warnings associated with Phoxillum Bk4/2.5.

What is Phoxillum Bk4/2.5 used for?

PRISMASOL and PHOXILLUM solutions are indicated in pediatric and adult patients for use as a replacement solution in Continuous Renal Replacement Therapy (CRRT) to replace plasma volume removed by ultrafiltration and to correct electrolyte and acid-base imbalances.They may also be used in case of drug poisoning when CRRT is used to remove dialyzable substances. PRISMASOL and PHOXILLUM solutions are indicated: As a replacement solution in Continuous Renal Replacement Therapy (CRRT) and in case of drug poisoning when CRRT is used to remove dialyzable substances (1)

Is Phoxillum Bk4/2.5 usage safe while breastfeeding? If a lactating mother is using it can there be any effect on growth or development of infant?

Phoxillum Bk4/2.5 is made up of Calcium chloride, Magnesium chloride, Sodium chloride, Potassium chloride, Sodium phosphate, dibasic, Sodium bicarbonate.Below is the analysis of usage of its active ingredients while breastfeeding, We suggest you to go through full analysis to understand the impact of Phoxillum Bk4/2.5 in breastfeeding.Please note that we have already provided safety rating to some of the ingredients but other ingredients does not have any safety rating and we are working on it.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers The components of PRISMASOL and PHOXILLUM solutions are excreted in human milk. Appropriate administration of PRISMASOL and PHOXILLUM solutions with monitoring of fluid, electrolyte, acid-base and glucose balance, is not expected to harm a nursing infant.

Phoxillum Bk4/2.5 Breastfeeding Analsys

Calcium chloride while Breastfeeding


Various calcium salts (Acetate, Carbonate, Chloride, Citrate, Phosphate, Gluceptate, Glucobionato, Lactate, Laxctobionato Pidolate, Silicate) are used in the management of hypocalcemia, supplements for treating calcium deficiency states and antacids ( Carbonate and Silicate) Daily requirement of calcium during lactation are 1 g (1.3 g in children under 20 years).Calcium supplements in the diet does not affect the concentration of calcium in milk.Excessive intake of calcium is not good for health. During lactation, consumption of calcium should not exceed 2.5 g a day. WHO List of Essential Medicines 2002 states that it is compatible with breastfeeding.

Sodium chloride while Breastfeeding


CAS Number: 7647-14-5

Sodium chloride either as cooking salt, or, as oral rehydration solution, or, as IV fluid, is entirely compatible with BF.

Potassium chloride while Breastfeeding


CAS Number: 7447-40-7

Human milk has a potassium concentration of 13 meq/L, almost a half of rehydration solution content and a quarter of maximal IV recommended dose. Potassium supplementation does not alter milk concentration without increasing mother’s serum concentration, which is strictly limited from 3,5 to 5,5 meq/L.

Sodium phosphate, dibasic while Breastfeeding


CAS Number: 7558-79-4

Phoxillum Bk4/2.5 and breastfeeding

Phosphates are used as a laxative and to clean the bowel before medical examinations.They base their action on the little or zero amount which is absorbed (Nice 2000), causing water to escape from the intestine and severe diarrhea.Keep this in mind in order to drink as much as needed and avoid dehydration of the nursing mother who is already producing about 1 litre of liquid in the form of milk a day. Since the last update, we have not found published data on its excretion in breast milk. Both sodium and phosphate are normal components of the body and are found in breast milk at concentrations different to plasma (Allen 1991). Temporary increases in plasma phosphate levels have been observed after the administration of sodium phosphate enema (Salix 2009, Ehrenpreis 2009). It is not known whether this may affect the concentration of phosphate in breast milk, but it is believed that the variation is minimal, temporary and does not have clinical repercussions in the infant. Expert authors consider phosphate-based laxatives compatible with breastfeeding (Nice 2000).

Sodium bicarbonate while Breastfeeding


CAS Number: 144-55-8

It is contained in preparations used for treatment of excessive gastric acidity, oral rehydration solutions and fluids for intravenous use that aim the correction of acute metabolic acidosis. Also used for long-standing treatment of chronic metabolic acidosis due to kidney malfunction. Oral bicarbonate solutions neutralize gastric acidity with production of Carbon Dioxide. The rest is absorbed by the gut. In the plasma, bicarbonate is kept at normal physiological range, with the excess eliminated by the kidney. Epithelial cells of the mammary gland regulate the entrance of sodium and bicarbonate into the mother's milk, with little effect on milk composition due to diet. Bicarbonate decreases secretion of Prolactin in cases of secondary Hyperprolactinemia due to metabolic acidosis, but does not affect production of the milk. WHO Model List of Essential Medicines (2002): compatible with breastfeeding

Phoxillum Bk4/2.5 Breastfeeding Analsys - 2

Magnesium chloride while Breastfeeding

CAS Number: 3344-18-1

No information is available on the clinical use of magnesium citrate during breastfeeding. However, other magnesium salts have been studied. Intravenous magnesium sulfate increases milk magnesium concentrations only slightly. Oral absorption of magnesium by the infant is poor, so maternal magnesium citrate is not expected to affect the breastfed infant's serum magnesium. Magnesium citrate supplementation during pregnancy might delay the onset of lactation, but it can be taken during breastfeeding and no special precautions are required.

Is Phoxillum Bk4/2.5 safe while breastfeeding

What should I do if already breastfed my kid after using Phoxillum Bk4/2.5?

We are not completely sure about safety of Phoxillum Bk4/2.5 in breastfeeding. We would suggest you to contact your doctor or health care provider and explain your situation with Phoxillum Bk4/2.5. If you observe anything abnormal with your baby please call 911 or contact emergency services in your area.

I am nursing mother and my doctor has suggested me to use Phoxillum Bk4/2.5, is it safe?

If your doctor considers Phoxillum Bk4/2.5 safe enough to prescribe for you that means its benefits outweigh its known risks.

If I am using Phoxillum Bk4/2.5, will my baby need extra monitoring?

Not Sure, Please check with your doctor or lactation consultant.

Who can I talk to if I have questions about usage of Phoxillum Bk4/2.5 in breastfeeding?

National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week