It is recommended to breastfeed exclusively for six months and then while introducing to other food sources extend it to twelve months. In this duration most mothers will need help of some sort of medication, It could be for short term like could and flue or it could be something chronic like Arthritis or Diabetes and here comes the question of safety of medication in use. In this post we will figure out what is Isentress | Raltegravir Tablet and whether its safe to use Isentress | Raltegravir Tablet while nursing or not.
What is Isentress | Raltegravir Tablet used for?
ISENTRESS® is indicated in combination with other antiretroviral agents for the treatment of human immunodeficiency virus (HIV-1) infection in patients 4 weeks of age and older. The use of other active agents with ISENTRESS is associated with a greater likelihood of treatment response [see Clinical Studies (14)] . ISENTRESS is a human immunodeficiency virus integrase strand transfer inhibitor (HIV-1 INSTI) indicated: In combination with other antiretroviral agents for the treatment of HIV-1 infection in patients 4 weeks of age and older ( 1). The use of other active agents with ISENTRESS is associated with a greater likelihood of treatment response ( 14).
I am breastfeeding mother and I am using Isentress | Raltegravir Tablet. Can it have any bad effect on my kid? Shall I search for better alternative?
Isentress | Raltegravir Tablet contains Raltegravir as active ingredients, . We do not have safety rating of Raltegravir but we do have analysis of Raltegravir, which is used in manufacturing of Isentress | Raltegravir Tablet. You can get a good idea about Isentress | Raltegravir Tablet usage while breastfeeding by going through our detailed analysis as below.
Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers Breastfeeding is not recommended while taking ISENTRESS. In addition, it is recommended that HIV-1-infected mothers not breastfeed their infants to avoid risking postnatal transmission of HIV-1. It is not known whether raltegravir is secreted in human milk. However, raltegravir is secreted in the milk of lactating rats. Mean drug concentrations in milk were approximately 3-fold greater than those in maternal plasma at a maternal dose of 600 mg/kg/day in rats. There were no effects in rat offspring attributable to exposure of ISENTRESS through the milk.
Isentress | Raltegravir Tablet Breastfeeding Analsys
Raltegravir while Breastfeeding
CAS Number: 518048-05-0
In the United States and other developed countries, HIV-infected mothers should generally not breastfeed their infants. No published information is available on the use of raltegravir during breastfeeding. In countries in which no acceptable, feasible, sustainable and safe replacement feeding is available, World Health Organization guidelines recommend that all women with an HIV infection who are pregnant or breastfeeding should be maintained on antiretroviral therapy for at least the duration of risk for mother-to-child transmission. Mothers should exclusively breastfeed their infants for the first 6 months of life; breastfeeding with complementary feeding should continue through 12 months of life. The first choice regimen for nursing mothers is tenofovir, efavirenz and either lamivudine or emtricitabine. If these drugs are unavailable, alternative regimens include: 1) zidovudine, lamivudine and efavirenz; 2) zidovudine, lamivudine and nevirapine; or 3) tenofovir, nevirapine and either lamivudine or emtricitabine. Exclusively breastfed infants should also receive 6 weeks of prophylaxis with nevirapine.
What if I already have used Isentress | Raltegravir Tablet?
We are not completely sure about safety of Isentress | Raltegravir Tablet in breastfeeding. We would suggest you to contact your doctor or health care provider and explain your situation with Isentress | Raltegravir Tablet. If you observe anything abnormal with your baby please call 911 or contact emergency services in your area.
I am nursing mother and my doctor has suggested me to use Isentress | Raltegravir Tablet, is it safe?
If your doctor considers Isentress | Raltegravir Tablet safe enough to prescribe for you that means its benefits outweigh its known risks.
If I am using Isentress | Raltegravir Tablet, will my baby need extra monitoring?
Not Sure, Please check with your doctor or lactation consultant.
Who can I talk to if I have questions about usage of Isentress | Raltegravir Tablet in breastfeeding?
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week