Nutrients from the food that you eat passes to your breast milk. Its good idea to take healthy diet while breastfeeding. You may need to consume more calories per day to support healthy body system. Some time it gets necessary take medicine while you are breastfeeding and as other food items passes into breast milk, medicine passes as well hence it becomes obvious to understand its effects while breastfeeding. We have analyzed many medications and in this sheet we will present some fact and known information associated with Piperacillin And Tazobactam Injection, Powder, For Solution while breast-feeding.
What is Piperacillin And Tazobactam Injection, Powder, For Solution used for?
1. INDICATIONS AND USAGE Piperacillin and tazobactum for injection is a combination penicillin-class antibacterial and β-lactamase inhibitor indicated for treatment of: Intra-abdominal infections (1.1) Skin and skin structure infections (1.2) Female pelvic infections (1.3) Community-acquired pneumonia (1.4) Nosocomial pneumonia (1.5) Piperacillin and tazobactam for injection is a combination product consisting of a penicillin-class antibacterial, piperacillin, and a β-lactamase inhibitor, tazobactam, indicated for the treatment of patients with moderate to severe infections caused by susceptible isolates of the designated bacteria in the conditions listed below. 1.1 Intra-abdominal Infections Appendicitis (complicated by rupture or abscess) and peritonitis caused by β-lactamase producing isolates of Escherichia coli or the following members of the Bacteroides fragilis group: B. fragilis, B. ovatus, B. thetaiotaomicron, or B. vulgatus. The individual members of this group were studied in fewer than 10 cases. 1.2 Skin and Skin Structure Infections Uncomplicated and complicated skin and skin structure infections, including cellulitis, cutaneous abscesses and ischemic/diabetic foot infections caused by β-lactamase producing isolates of Staphylococcus aureus. 1.3 Female Pelvic Infections Postpartum endometritis or pelvic inflammatory disease caused by β-lactamase producing isolates of Escherichia coli. 1.4 Community-acquired Pneumonia Community-acquired pneumonia (moderate severity only) caused by β-lactamase producing isolates of Haemophilus influenzae. 1.5 Nosocomial Pneumonia Nosocomial pneumonia (moderate to severe) caused by β-lactamase producing isolates of Staphylococcus aureus and by piperacillin/tazobactam-susceptible Acinetobacter baumannii, Haemophilus influenzae, Klebsiella pneumoniae, and Pseudomonas aeruginosa (Nosocomial pneumonia caused by P. aeruginosa should be treated in combination with an aminoglycoside) [see Dosage and Administration (2) ]. To reduce the development of drug-resistant bacteria and maintain the effectiveness of piperacillin and tazobactam for injection and other antibacterial drugs, piperacillin and tazobactam for injection should be used only to treat infections that are proven or strongly suspected to be caused by bacteria. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
Can I continue breastfeeding if I am using Piperacillin And Tazobactam Injection, Powder, For Solution? How long does it stays in breast milk?
Piperacillin And Tazobactam Injection, Powder, For Solution Contains 2 active ingredients that are Piperacillin anhydrous, Tazobactam. We do have breastfeeding analysis and safety rating of some of the active ingredients but unfortunately we do not have any information of some of active ingredients used. Below we have provided whatever information we do have. But please do not take any decision based on below provided information and contact your health care provider as this information is incomplete.
Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers Piperacillin is excreted in low concentrations in human milk; tazobactam concentrations in human milk have not been studied. Caution should be exercised when piperacillin and tazobactam for injection is administered to a nursing woman.
Piperacillin And Tazobactam Injection, Powder, For Solution Breastfeeding Analsys
Piperacillin anhydrous while Breastfeeding Safe
CAS Number: 59703-84-3
Ureidopenicillin with a similar use to ticarcillin (see specific info). It is excreted into breastmilk in a clinically insignificant amount (Baier 1982, Chaplin 1982, Wyeth 2007). Because it lacks of oral bioavailability, seems difficult any pass to the infant’s plasma through the breast milk ingested, except on premature infants and immediate neonatal period, in which there may be an increased intestinal permeability. Authorized use in infants and small infants (Chen 2009). Be aware of the likelihood of false negative cultures of febrile infants whose mothers are on antibiotics, as well as the possibility of gastroenteritis due to imbalanced intestinal flora (Ito 1993).
Piperacillin And Tazobactam Injection, Powder, For Solution Breastfeeding Analsys - 2
Piperacillin anhydrous while Breastfeeding
CAS Number: 61477-96-1
Limited information indicates that piperacillin produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush have been reported with penicillins, but these effects have not been adequately evaluated. Piperacillin is acceptable in nursing mothers.
I am nursing mother and I have already used Piperacillin And Tazobactam Injection, Powder, For Solution, what should I do?
Not much study has been done on safety of Piperacillin And Tazobactam Injection, Powder, For Solution in breastfeeding and its ingredients. Even we do not have complete information about usage of Piperacillin And Tazobactam Injection, Powder, For Solution in breastfeeding so at this point a trained medical professional could be your best bet. If you observe anything abnormal with your baby please contact 911.
My health care provider has asked me to use Piperacillin And Tazobactam Injection, Powder, For Solution, what to do?
If your doctor considers Piperacillin And Tazobactam Injection, Powder, For Solution safe enough to prescribe for you that means its benefits should outweigh its known risks for you.
If I am using Piperacillin And Tazobactam Injection, Powder, For Solution, will my baby need extra monitoring?
We are not Sure, Please check with your healthcare provider or doctor.
Who can I talk to if I have questions about usage of Piperacillin And Tazobactam Injection, Powder, For Solution in breastfeeding?
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week