Histex-dm while Breastfeeding
Modern medicine has evolved so much so that sooner or later every breastfeeding mother needs to take it in one form or other. Medication that is present in mothers blood will transfer into her breast milk to some extent. Most drugs do so at low levels and pose no real risk to infants but then there are some exceptions. In This post will discuss whether Histex-dm is safe in breast-feeding or not.

What is Histex-dm used for?

temporarily relieves these symptoms due to common cold, hay fever (allergic rhinitis) or other upper respiratory allergies: cough due to minor throat or bronchial irritation runny nose sneezing itching of the nose or throat itchy, watery eyes nasal congestion reduces swelling of nasal passages

Purpose: Active ingredients (in each 5 mL teaspoonful) Purpose Dextromethorphan HBr 20 mg Cough Suppressant Phenylephrine HCl 10 mg Decongestant Triprolidine HCl 2.5 mg Antihistamine

Is Histex-dm usage safe while breastfeeding? If a lactating mother is using it can there be any effect on growth or development of infant?

Histex-dm low risk for breastfeeding
Task to evaluate the effect of Histex-dm is quite difficult as it consist mainly 3 ingredients. However we have analyzed all 3 active ingredients and have reached a conclusion that Histex-dm poses low risk while breastfeeding. Below we have summarized our analysis of each 3 ingredients.

Histex-dm Breastfeeding Analsys

Dextromethorphan hydrobromide while Breastfeeding


CAS Number: 125-71-3

Cough suppressant related with morphine and codeine which is lacking of analgesic or sedative properties. Commonly prescribed by pediatricians. On latest update relevant data on breastfeeding was not found. Because reported low toxicity and mild side effect it is considered to be safe while breastfeeding. Frequently associated to caffeine and other products that are usually compatible with breastfeeding. Avoid use of multiple drug and alcohol containing medication.

Phenylephrine hydrochloride while Breastfeeding

Low Risk

CAS Number: 59-42-7

Used on topical decongestant solutions for nose drops at low concentration. 10% midriatic eye drops are available. Because low concentration is used on nose and ophtalmic drops a significant excretion into breast milk is unlikely. Low oral biodisponibility minimizes any risk of harmful effect in the infant. Authorized for nasal or ophtalmic use on children aged younger than 1 year. Although on latest update relevant data on breastfeeding was not found it is considered to be safe when minimal dose is used. Avoid excessive or long term use. A related drug Pseudoephedrine can inhibit milk production. It would be advisable to press on the lachrimal sac to minimize absorption.

Triprolidine hydrochloride while Breastfeeding


CAS Number: 550-70-9

1st-generation-antihistamine and alkylamine-type drug with a moderate sedative effect. It is excreted into breastmilk in a clinically non-significant amount with plasma levels that were undetectable or very low in infants whose mothers had received this medication (Findlay 1984). First-generation antihistamines may decrease prolactin levels and interfere with milk production during the first few weeks after birth (Pontiroli 1981, Messinis 1985).Monitor drowsiness and inadequate feeding on the infant.It is not recommended bed-sharing if you are taking this medicine (UNICEF 2006, ABM 2008, Landa 2012, UNICEF 2013). The American Academy of Pediatrics considers this medication as usually compatible with breastfeeding.

Histex-dm Breastfeeding Analsys - 2

Dextromethorphan hydrobromide while Breastfeeding

CAS Number: 125-71-3

Neither the excretion of dextromethorphan in milk nor its effect on breastfed infants have been studied. It is unlikely that with usual maternal doses amounts in breastmilk would harm the nursing infant, especially in infants over 2 months of age. It is best to avoid the use of products with a high alcohol content while nursing.

Phenylephrine hydrochloride while Breastfeeding

CAS Number: 59-42-7

The oral bioavailability of phenylephrine is only about 40%,[1] so the drug is unlikely to reach the infant in large amounts. However, intravenous or oral administration of phenylephrine might decrease milk production. Because no information is available on the use of oral phenylephrine during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.Phenylephrine nasal spray or ophthalmic drops are less likely to decrease lactation. To substantially diminish the effect of the drug after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

Triprolidine hydrochloride while Breastfeeding

CAS Number: 486-12-4

Small, occasional doses of triprolidine would not be expected to cause any adverse effects in breastfed infants. Larger doses or more prolonged use may cause effects in the infant or decrease the milk supply, particularly in combination with a sympathomimetic such as pseudoephedrine or before lactation is well established. The nonsedating antihistamines are preferred alternatives.

I am nursing mother and I have already used Histex-dm, what should I do?

Histex-dm is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Histex-dm so you should inform him based on your convenience.

I am nursing mother and my doctor has suggested me to use Histex-dm, is it safe?

Though Histex-dm dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.

If I am using Histex-dm, will my baby need extra monitoring?

Not much monitoring required while using Histex-dm

Who can I talk to if I have questions about usage of Histex-dm in breastfeeding?

National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week