Most health expert recommend six month of exclusive breastfeeding but statics suggest that numbers are not good, almost 95% mothers start breastfeeding but this number drops to 40% in first three month and further it drops to 15% till fifth month. Sometime its due to need of medication usage. Because of these statics its important to provide good information on safety of drugs in breastfeeding so that it can be improved when possible. In this FAQ sheet we will discuss about exposure to Propofol Injection, Emulsion while breastfeeding. We will also discuss about common side effects and warnings associated with Propofol Injection, Emulsion.
What is Propofol Injection, Emulsion used for?
Propofol injectable emulsion is an IV sedative-hypnotic agent that can be used as described in the table below. TABLE 3. INDICATIONS FOR PROPOFOL INJECTABLE EMULSION Indication Approved Patient Population Initiation and maintenance of Monitored Anesthesia Adults only Care (MAC) sedation Combined sedation and regional anesthesia Adults only (See PRECAUTIONS ) Induction of General Anesthesia Patients ≥ 3 years of age Maintenance of General Anesthesia Patients ≥ 2 months of age Intensive Care Unit (ICU) sedation of intubated, mechanically ventilated patients Adults only Safety, effectiveness and dosing guidelines for propofol have not been established for MAC Sedation in the pediatric population; therefore, it is not recommended for this use. (See PRECAUTIONS - Pediatric use.) Propofol is not recommended for induction of anesthesia below the age of 3 years or for maintenance of anesthesia below the age of 2 months because its safety and effectiveness have not been established in those populations. In the Intensive Care Unit (ICU), propofol can be administered to intubated, mechanically ventilated adult patients to provide continuous sedation and control of stress responses, only by persons skilled in the medical management of critically ill patients and trained in cardiovascular resuscitation and airway management. Propofol is not indicated for use in Pediatric ICU sedation since the safety of this regimen has not been established. (See PRECAUTIONS - Pediatric use.) Propofol is not recommended for obstetrics, including Cesarean section deliveries. Propofol crosses the placenta, and as with other general anesthetic agents, the administration of propofol may be associated with neonatal depression. (See PRECAUTIONS .) Propofol is not recommended for use in nursing mothers because propofol has been reported to be excreted in human milk, and the effects of oral absorption of small amounts of propofol are not known. (See PRECAUTIONS .)
I am breastfeeding mother and I am using Propofol Injection, Emulsion. Can it have any bad effect on my kid? Shall I search for better alternative?
As per our analysis Propofol Injection, Emulsion contains only one ingredient and that is Propofol. We have analyzed Propofol and it seems to be safe to use Propofol while breastfeeding, that means usage of Propofol Injection, Emulsion shall be safe while breastfeeding. Below you can check more details of Propofol usage in breastfeeding. We recommend you to go through provided detailed analysis as below take decision accordingly.
Statement of Manufacturer/Labeler about breastfeeding usage
Nursing mothers Propofol is not recommended for use in nursing mothers because propofol has been reported to be excreted in human milk and the effects of oral absorption of small amounts of propofol are not known.
Propofol Injection, Emulsion Breastfeeding Analsys
Propofol while Breastfeeding Safe
CAS Number: 2078-54-8
Because of a high protein-binding capacity and a high volume of distribution, excretion into the breast milk is non-significant. No side-effects were observed in breastfed infants of mothers who were administered this medication. The nursing mother may breastfeed the baby as soon as she is recovered from anesthesia. A transient increase in Prolactin plasma levels has been observed with Propofol anesthesia. A case of green-bluish discoloration of the milk has been reported after administration of Propofol plus other drugs. Authorized medication for use in infants older than 1 month.
Propofol Injection, Emulsion Breastfeeding Analsys - 2
Propofol while Breastfeeding
CAS Number: 2078-54-8
Amounts of propofol in milk are very small and are not expected to be absorbed by the infant. Although one expert panel recommends withholding nursing for an unspecified time after propofol administration, most recommend that breastfeeding can be resumed as soon as the mother has recovered sufficiently from general anesthesia to nurse and that discarding milk is unnecessary. When a combination of anesthetic agents is used for a procedure, follow the recommendations for the most problematic medication used during the procedure. General anesthesia for cesarean section using propofol as a component for induction may delay the onset of lactation. In one study, breastfeeding before general anesthesia induction reduced requirements of propofol and sevoflurane compared to those of nursing mothers whose breastfeeding was withheld or nonnursing women. In one case, milk was noted to be green in color 8 hours after a procedure in which propofol was administered; however, several other medications were also used during the procedure.
What should I do if already breastfed my kid after using Propofol Injection, Emulsion?
It is always a good idea to keep your healthcare provider or doctor informed about your drug usage during pregnancy and breastfeeding but if you have not informed your doctor about Propofol Injection, Emulsion and have used it then do not panic as Propofol Injection, Emulsion is mostly safe in breastfeeding and should not cause any harm to your baby.
I am nursing mother and my doctor has suggested me to use Propofol Injection, Emulsion, is it safe?
Usage of Propofol Injection, Emulsion is safe for nursing mothers and baby, No worries.
If I am using Propofol Injection, Emulsion, will my baby need extra monitoring?
Who can I talk to if I have questions about usage of Propofol Injection, Emulsion in breastfeeding?
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week