American Academy of Pediatrics and other medical experts exclusively recommend to breastfeed the baby for first 6 months. Once you introduce baby to other foods it is recommended to breastfeed for at least first year of babys life. Taking medication while breastfeeding could be tricky as most drugs pass in breast milk. In this article we will evaluate Amiodarone Hydrochloride | Barr Laboratories Inc. for its safety in breastfeeding.
What is Amiodarone Hydrochloride | Barr Laboratories Inc. used for?
: Because of its life-threatening side effects and the substantial management difficulties associated with its use (see WARNINGS below), amiodarone hydrochloride tablets are indicated only for the treatment of the following documented, life-threatening recurrent ventricular arrhythmias when these have not responded to documented adequate doses of other available antiarrhythmics or when alternative agents could not be tolerated. Recurrent ventricular fibrillation. Recurrent hemodynamically unstable ventricular tachycardia. As is the case for other antiarrhythmic agents, there is no evidence from controlled trials that the use of Amiodarone Hydrochloride Tablets favorably affects survival. Amiodarone should be used only by physicians familiar with and with access to (directly or through referral) the use of all available modalities for treating recurrent life-threatening ventricular arrhythmias, and who have access to appropriate monitoring facilities, including in-hospital and ambulatory continuous electrocardiographic monitoring and electrophysiologic techniques. Because of the life-threatening nature of the arrhythmias treated, potential interactions with prior therapy, and potential exacerbation of the arrhythmia, initiation of therapy with amiodarone should be carried out in the hospital.
Is using Amiodarone Hydrochloride | Barr Laboratories Inc. unsafe in breastfeeding? Can there be bad consequences for baby if I use it while breastfeeding?
As Amiodarone Hydrochloride | Barr Laboratories Inc. is made of only Amiodarone hydrochloride, and Amiodarone hydrochloride is unsafe to use in breastfeeding we can safely reach on conclusion that Amiodarone Hydrochloride | Barr Laboratories Inc. is also unsafe to use while breastfeeding. Below is detailed analysis of Amiodarone hydrochloride and Amiodarone Hydrochloride | Barr Laboratories Inc. during location. We recommend you to go through provided detailed analysis as below take decision accordingly. We also recommend you talk to your health care provider before making final decision.
Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers: Amiodarone and one of its major metabolites, desethylamiodarone (DEA), are excreted in human milk, suggesting that breast-feeding could expose the nursing infant to a significant dose of the drug. Nursing offspring of lactating rats administered amiodarone have been shown to be less viable and have reduced body-weight gains. Therefore, when amiodarone therapy is indicated, the mother should be advised to discontinue nursing.
Amiodarone Hydrochloride | Barr Laboratories Inc. Breastfeeding Analsys
Amiodarone hydrochloride while Breastfeeding Unsafe
CAS Number: 1951-25-3
A published case of infant hypothyroidism. Others have reported lab controlled cases with harmless effect in breastfed babies.
Amiodarone Hydrochloride | Barr Laboratories Inc. Breastfeeding Analsys - 2
Amiodarone hydrochloride while Breastfeeding
CAS Number: 1951-25-3
Breastmilk and infant serum levels of amiodarone and its active metabolite are somewhat unpredictable, but can be high during breastfeeding. The infant receives an estimated dose of amiodarone plus desethylamiodarone ranging from 3.5 to 45% of the mother's weight-adjusted amiodarone dose, with a median dose of about 11%. Infant serum levels of the drug plus metabolite range from 14 to 74% of simultaneous maternal levels, with the higher values reflecting transplacental passage of the drug. In addition to possible cardiac effects, these compounds contain a large amount of iodine which may be released during metabolism. Thyroid dysfunction was reported in one breastfed infant. Even if the drug were discontinued at birth, the mother would continue to excrete amiodarone and its metabolite (and possibly large amounts of iodine) into breastmilk for days to weeks. Some investigators believe that breastfeeding can be undertaken during maternal amiodarone use with periodic monitoring of infant cardiac and thyroid function status, especially if only a single dose of amiodarone is given. Infant serum levels of amiodarone and desethylamiodarone may be useful for ruling out cardiac effects of the drug. If hypothyroidism develops, therapy should be promptly initiated.
I already used Amiodarone Hydrochloride | Barr Laboratories Inc. and meanwhile I breastfed my baby should I be concerned?
We have already established that Amiodarone Hydrochloride | Barr Laboratories Inc. is unsafe in breastfeeding and breastfeeding while using Amiodarone Hydrochloride | Barr Laboratories Inc. is not a good idea however if have already used and then breastfed the baby then you shall monitor the behavior and health of baby closely and inform your doctor as soon as possible. In case of emergency please call 911.
My health care provider has asked me to use Amiodarone Hydrochloride | Barr Laboratories Inc., what to do?
If your doctor knows that you are breastfeeding mother and still prescribes Amiodarone Hydrochloride | Barr Laboratories Inc. then there must be good reason for that as Amiodarone Hydrochloride | Barr Laboratories Inc. is considered unsafe, It usually happens when doctor finds that overall advantage of taking outweighs the overall risk.
If I am using Amiodarone Hydrochloride | Barr Laboratories Inc., will my baby need extra monitoring?
Yes, Extra monitoring is required if mother is using Amiodarone Hydrochloride | Barr Laboratories Inc. and breastfeeding as it is considered unsafe for baby.
Who can I talk to if I have questions about usage of Amiodarone Hydrochloride | Barr Laboratories Inc. in breastfeeding?
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week