Modern medicine has evolved so much so that sooner or later every breastfeeding mother needs to take it in one form or other. Medication that is present in mothers blood will transfer into her breast milk to some extent. Most drugs do so at low levels and pose no real risk to infants but then there are some exceptions. In This post will discuss whether Clopidogrel Kit Kit is safe in breast-feeding or not.
What is Clopidogrel Kit Kit used for?
Clopidogrel bisulfate is a P2Y12 platelet inhibitor indicated for: •Acute coronary syndrome - For patients with non-ST-segment elevation ACS [unstable angina (UA)/non-ST-elevation myocardial infarction (NSTEMI)], clopidogrel bisulfate has been shown to reduce the rate of myocardial infarction (MI) and stroke. (1.1) - For patients with ST-elevation myocardial infarction (STEMI), clopidogrel bisulfate has been shown to reduce the rate of MI and stroke. (1.1) •Recent MI, recent stroke, or established peripheral arterial disease. Clopidogrel bisulfate has been shown to reduce the rate of MI and stroke. (1.2) 1.1 Acute Coronary Syndrome (ACS) •Clopidogrel tablets are indicated to reduce the rate of myocardial infarction and stroke (MI) in patients with non-ST-segment elevation ACS [unstable angina (UA)/non-ST-elevation myocardial infarction (NSTEMI)], including patients who are to be managed medically and those who are to be managed with coronary revascularization. Clopidogrel should be administered in conjunction with aspirin. •Clopidogrel tablets are indicated to reduce the rate of myocardial infarction and stroke in patients with acute ST-elevation myocardial infarction (STEMI) who are to be managed medically. Clopidogrel bisulfate should be administered in conjunction with aspirin. 1.2 Recent MI, Recent Stroke, or Established Peripheral Arterial Disease In patients with established peripheral arterial disease or with a history of recent myocardial infarction (MI) or recent stroke clopidogrel bisulfate is indicated to reduce the rate of MI and stroke.
Is Clopidogrel Kit Kit usage safe while breastfeeding? If a lactating mother is using it can there be any effect on growth or development of infant?
Clopidogrel Kit Kit consists two active ingredients Clopidogrel and Aspirin and as per our analysis of both we have determined the Clopidogrel Kit Kit is unsafe during breastfeeding. We recommend you to check both ingredients below for better understanding of Clopidogrel Kit Kit in breastfeeding.
Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers Studies in rats have shown that clopidogrel and/or its metabolites are excreted in the milk. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from clopidogrel, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Clopidogrel Kit Kit Breastfeeding Analsys
Clopidogrel while Breastfeeding Unsafe
CAS Number: 90055-48-4
Though no adverse effects have been described yet, it should be given cautiously since a potent inhibitory effect on platelet aggregation is likely.
Aspirin while Breastfeeding Low Risk
CAS Number: 50-78-2
Excreted in non-significant amount into breast milk. Reye’s Syndrome has never been reported due to ASA through breast milk. It is thought to be highly unlikely to occur after isolated or small doses like those used for treatment of thrombosis or anti-abortion therapy. At high maternal dose, one case (dubious) of salicylic intoxication in the neonatal period and another case of thrombocytopenia in an infant have been reported. Likelihood of hemolysis should be considered in those patients with G6PD-deficiency. WHO Model List of Essential Medication: compatible while breastfeeding when used occasionally or small dose for antithrombotic prophylaxis management.
Clopidogrel Kit Kit Breastfeeding Analsys - 2
Clopidogrel while Breastfeeding
CAS Number: 120202-66-6
No published information is available on the use of clopidogrel during breastfeeding. The manufacturer reports that no adverse effects have been observed in breastfed infants with maternal clopidogrel use during lactation in a small number of postmarketing cases. If clopidogrel is required by the mother, it is not a reason to discontinue breastfeeding. However, since no published information is available on the use of clopidogrel during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Aspirin while Breastfeeding
CAS Number: 50-78-2
After aspirin ingestion, salicylic acid is excreted into breastmilk, with higher doses resulting in disproportionately higher milk levels. Long-term, high-dose maternal aspirin ingestion probably caused metabolic acidosis in one breastfed infant. Reye's syndrome is associated with aspirin administration to infants with viral infections, but the risk of Reye's syndrome from salicylate in breastmilk is unknown. An alternate drug is preferred over continuous high-dose, aspirin therapy. After daily low-dose aspiring (75 to 325 mg daily), no aspirin is excreted into breastmilk and salicylate levels are low. Daily low-dose aspirin therapy may be considered as an antiplatelet drug for use in breastfeeding women..
I am nursing mother and I have already used Clopidogrel Kit Kit, what should I do?
If you observer abnormal behavior or any other health issue in infant then you should immediately call 911 or contact other contact other emergency service provider in your area otherwise closely monitor the baby and inform your doctor about your Clopidogrel Kit Kit usage and time interval of breastfeeding.
I am nursing mother and my doctor has suggested me to use Clopidogrel Kit Kit, is it safe?
If your doctor knows that you are breastfeeding mother and still prescribes Clopidogrel Kit Kit then there must be good reason for that as Clopidogrel Kit Kit is considered unsafe, It usually happens when doctor finds that overall advantage of taking outweighs the overall risk.
If I am using Clopidogrel Kit Kit, will my baby need extra monitoring?
Yes, Extra monitoring is required if mother is using Clopidogrel Kit Kit and breastfeeding as it is considered unsafe for baby.
Who can I talk to if I have questions about usage of Clopidogrel Kit Kit in breastfeeding?
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week