Amiodarone Hydrochloride 200 Mg Breastfeeding
It is recommended to breastfeed exclusively for six months and then while introducing to other food sources extend it to twelve months. In this duration most mothers will need help of some sort of medication, It could be for short term like could and flue or it could be something chronic like Arthritis or Diabetes and here comes the question of safety of medication in use. In this post we will figure out what is Amiodarone Hydrochloride 200 Mg and whether its safe to use Amiodarone Hydrochloride 200 Mg while nursing or not.

What is Amiodarone Hydrochloride 200 Mg used for?


Because of its life-threatening side effects and the substantial management difficulties associated with its use (see WARNINGS below), amiodarone is indicated only for the treatment of the following documented, life-threatening recurrent ventricular arrhythmias when these have not responded to documented adequate doses of other available antiarrhythmics or when alternative agents could not be tolerated. Recurrent ventricular fibrillation. Recurrent hemodynamically unstable ventricular tachycardia. As is the case for other antiarrhythmic agents, there is no evidence from controlled trials that the use of amiodarone hydrochloride tablets favorably affects survival. Amiodarone should be used only by physicians familiar with and with access to (directly or through referral) the use of all available modalities for treating recurrent life-threatening ventricular arrhythmias, and who have access to appropriate monitoring facilities, including in-hospital and ambulatory continuous electrocardiographic monitoring and electrophysiologic techniques. Because of the life-threatening nature of the arrhythmias treated, potential interactions with prior therapy, and potential exacerbation of the arrhythmia, initiation of therapy with amiodarone should be carried out in the hospital.

Amiodarone Hydrochloride 200 Mg while breastfeeding safe or not? Can there be any side effects for infant while using it during breastfeeding?

Amiodarone Hydrochloride 200 Mg high risk while breastfeeding
As Amiodarone Hydrochloride 200 Mg is made of only Amiodarone hydrochloride, and Amiodarone hydrochloride is unsafe to use in breastfeeding we can safely reach on conclusion that Amiodarone Hydrochloride 200 Mg is also unsafe to use while breastfeeding. Below is detailed analysis of Amiodarone hydrochloride and Amiodarone Hydrochloride 200 Mg during location. We recommend you to go through provided detailed analysis as below take decision accordingly. We also recommend you talk to your health care provider before making final decision.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers: Amiodarone and one of its major metabolites, desethylamiodarone (DEA), are excreted in human milk, suggesting that breast-feeding could expose the nursing infant to a significant dose of the drug. Nursing offspring of lactating rats administered amiodarone have been shown to be less viable and have reduced body-weight gains. Therefore, when amiodarone therapy is indicated, the mother should be advised to discontinue nursing.

Amiodarone Hydrochloride 200 Mg Breastfeeding Analsys


Amiodarone hydrochloride while Breastfeeding

Unsafe

CAS Number: 1951-25-3

A published case of infant hypothyroidism. Others have reported lab controlled cases with harmless effect in breastfed babies.


Amiodarone Hydrochloride 200 Mg Breastfeeding Analsys - 2


Amiodarone hydrochloride while Breastfeeding

CAS Number: 1951-25-3

Breastmilk and infant serum levels of amiodarone and its active metabolite are somewhat unpredictable, but can be high during breastfeeding. The infant receives an estimated dose of amiodarone plus desethylamiodarone ranging from 3.5 to 45% of the mother's weight-adjusted amiodarone dose, with a median dose of about 11%.[1][2][3][4] Infant serum levels of the drug plus metabolite range from 14 to 74% of simultaneous maternal levels, with the higher values reflecting transplacental passage of the drug.[2][3][4] In addition to possible cardiac effects, these compounds contain a large amount of iodine which may be released during metabolism. Thyroid dysfunction was reported in one breastfed infant. Even if the drug were discontinued at birth, the mother would continue to excrete amiodarone and its metabolite (and possibly large amounts of iodine) into breastmilk for days to weeks. Some investigators believe that breastfeeding can be undertaken during maternal amiodarone use with periodic monitoring of infant cardiac and thyroid function status,[5][6] especially if only a single dose of amiodarone is given.[7] Infant serum levels of amiodarone and desethylamiodarone may be useful for ruling out cardiac effects of the drug. If hypothyroidism develops, therapy should be promptly initiated.



What if I already have used Amiodarone Hydrochloride 200 Mg?

If you observer abnormal behavior or any other health issue in infant then you should immediately call 911 or contact other contact other emergency service provider in your area otherwise closely monitor the baby and inform your doctor about your Amiodarone Hydrochloride 200 Mg usage and time interval of breastfeeding.


I am nursing mother and my doctor has suggested me to use Amiodarone Hydrochloride 200 Mg, is it safe?

If your doctor knows that you are breastfeeding mother and still prescribes Amiodarone Hydrochloride 200 Mg then there must be good reason for that as Amiodarone Hydrochloride 200 Mg is considered unsafe, It usually happens when doctor finds that overall advantage of taking outweighs the overall risk.


If I am using Amiodarone Hydrochloride 200 Mg, will my baby need extra monitoring?

Yes, Extra monitoring is required if mother is using Amiodarone Hydrochloride 200 Mg and breastfeeding as it is considered unsafe for baby.


Who can I talk to if I have questions about usage of Amiodarone Hydrochloride 200 Mg in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week