Crema Nera Extrema Spf 14 | Avobenzone, Homosalate, Octisalate, Octocrylene Cream Breastfeeding
American Academy of Pediatrics and other medical experts exclusively recommend to breastfeed the baby for first 6 months. Once you introduce baby to other foods it is recommended to breastfeed for at least first year of babys life. Taking medication while breastfeeding could be tricky as most drugs pass in breast milk. In this article we will evaluate Crema Nera Extrema Spf 14 | Avobenzone, Homosalate, Octisalate, Octocrylene Cream for its safety in breastfeeding.

What is Crema Nera Extrema Spf 14 | Avobenzone, Homosalate, Octisalate, Octocrylene Cream ?


helps prevent sunburn

Brief: Sunscreen

Can I use Crema Nera Extrema Spf 14 | Avobenzone, Homosalate, Octisalate, Octocrylene Cream while breastfeeding?

Crema Nera Extrema Spf 14 | Avobenzone, Homosalate, Octisalate, Octocrylene Cream high risk while breastfeeding
There are total 4 active ingredients in Crema Nera Extrema Spf 14 | Avobenzone, Homosalate, Octisalate, Octocrylene Cream which makes it a complicated task to assess the effect of Crema Nera Extrema Spf 14 | Avobenzone, Homosalate, Octisalate, Octocrylene Cream on breastfeeding. Here on drlact after analyzing all 4 ingredients we have reached on conclusion that Crema Nera Extrema Spf 14 | Avobenzone, Homosalate, Octisalate, Octocrylene Cream is unsafe in breastfeeding. Below is our summarized analysis of Avobenzone, Homosalate, Octisalate, Octocrylene.

Avobenzone and Breastfeeding

Safe

Not much study has been done on effects of topical usage of Avobenzone during breast feeding however it is known to penetrate the skin in very limited quantity. Its not very likely to have adverse effects in breastfed infants.

Note: Study and data for tropical use only, Breakdown product causes relatively high rates of skin allergy hence stabilization is required.

Warning: Tropical usage in breast area shall be avoided to prevent the Avobenzone passing orally in Infants.

Homosalate and Breastfeeding

Unsafe

Homosalate has been found in mothers milk, its skin penetration rate is less than 1% in human and laboratory studies. Some studies suggest that Homosalate disrupts estrogen, androgen and progesterone levels. As not much study has been done on effects of Homosalate during breast feeding its recommended to use safe alternatives.

Note: Study and data for tropical use only

Warning: Tropical usage in breast area shall be avoided to prevent the Homosalate passing orally in Infants.

Octisalate and Breastfeeding

Low Risk

Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen. Salicylates are weak UVB absorbers and they are generally used in combination with other UV filters

Octisalate rarely causes allergies in tropical usage. Not much study has been done on effects of topical usage of Octisalate during breast feeding however it is known to penetrate the skin hence itís better to use other alternatives.

FDA study found blood levels 10 times above cutoff for systemic exposure, skin penetration in lab studies has been observed

Note: Study and data for tropical use only

Warning: Tropical usage in breast area shall be avoided to prevent the Octisalate passing orally in Infants.

Octocrylene and Breastfeeding

Safe

Based on the current available safety data, octocrylene used as a UV filter in cosmetic products at a concentration of 10% can be considered as safe. There was no evidence of any endocrine disruption potential from experimental studies which demonstrated no adverse effects on reproductive (e.g. oestrus cycle, epididymal and testicular sperm parameters) and developmental parameters. Effects on thyroid reported in repeated toxicity studies conducted in rats at very high doses are species?specific and not relevant considering the doses at which octocrylene is used in human.

Four studies on the transdermal absorption of octocrylene are available in the scientific literature, and an additional study is available in ECHA summaries of safety data. Dermal absorption studies of octocrylene showed that most octocrylene concentrations are found in the stratum corneum and that very few quantities are found in the epidermis (0.4%) and in the receptor fluid (<0.05%). In vivo, a very recent study in human volunteers showed systemic exposure to octocrylene with maximal concentrations ranging from 2.9 to 7.8 ng/mL under indoor maximal use conditions. Octocrylene has been found at very low amounts in human milk, and some metabolites of octocrylene were primarily detected in urine of volunteers using sunscreen products.

No systemic effects were reported after dermal exposure to octocrylene in rabbits at very high dose (534 mg/kg bw/day) compared with those used in cosmetic products. After oral exposure, effects on liver and thyroid were reported in a study conducted in rats at high doses (340 and 1085 mg/kg bw/day in males). These effects were investigated in an additional mechanistic study which showed that effects on thyroid were indirect and due to hepatic enzyme induction potential of octocrylene in rats at very high oral doses.

Based on available animal data, octocrylene does not induce developmental or teratogenic effects. In an extended one?generation reproductive toxicity study, only rats treated with the highest dose of octocrylene via oral route showed a decrease in the number of implantation sites and consequently a low number of pups. This very high dose of 550 mg/kg bw/day cannot be considered to be relevant to the dermal use of octocrylene as a cosmetic ingredient. Moreover, no other effects on male and female fertility and reproductive parameters such as oestrus cycle, epididymal and testicular sperm parameters were observed in all groups tested. Regarding pups, no effects on sexual and neurodevelopmental parameters were observed.

Note: Study and data for tropical use only

Warning: Tropical usage in breast area shall be avoided to prevent the Octocrylene passing orally in Infants. In some rare cases it can cause skin allergy.


I already used Crema Nera Extrema Spf 14 | Avobenzone, Homosalate, Octisalate, Octocrylene Cream and meanwhile I breastfed my baby should I be concerned?

We have already established that Crema Nera Extrema Spf 14 | Avobenzone, Homosalate, Octisalate, Octocrylene Cream is unsafe in breastfeeding and breastfeeding while using Crema Nera Extrema Spf 14 | Avobenzone, Homosalate, Octisalate, Octocrylene Cream is not a good idea however if have already used and then breastfed the baby then you shall monitor the behavior and health of baby closely and inform your doctor as soon as possible. In case of emergency please call 911.


My doctor has prescribed me Crema Nera Extrema Spf 14 | Avobenzone, Homosalate, Octisalate, Octocrylene Cream, what should I do?

If your doctor knows that you are breastfeeding mother and still prescribes Crema Nera Extrema Spf 14 | Avobenzone, Homosalate, Octisalate, Octocrylene Cream then there must be good reason for that as Crema Nera Extrema Spf 14 | Avobenzone, Homosalate, Octisalate, Octocrylene Cream is considered unsafe, It usually happens when doctor finds that overall advantage of taking outweighs the overall risk.


If I am using Crema Nera Extrema Spf 14 | Avobenzone, Homosalate, Octisalate, Octocrylene Cream, will my baby need extra monitoring?

Yes, Extra monitoring is required if mother is using Crema Nera Extrema Spf 14 | Avobenzone, Homosalate, Octisalate, Octocrylene Cream and breastfeeding as it is considered unsafe for baby.


Who can I talk to if I have questions about usage of Crema Nera Extrema Spf 14 | Avobenzone, Homosalate, Octisalate, Octocrylene Cream in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week