American Academy of Pediatrics and other medical experts exclusively recommend to breastfeed the baby for first 6 months. Once you introduce baby to other foods it is recommended to breastfeed for at least first year of babys life. Taking medication while breastfeeding could be tricky as most drugs pass in breast milk. In this article we will evaluate Lisinopril And Hydrochlorothiazide Lisinopril 50 Mg, Hydrochlorothiazide 50 Mg for its safety in breastfeeding.
What is Lisinopril And Hydrochlorothiazide Lisinopril 50 Mg, Hydrochlorothiazide 50 Mg ?
Lisinopril and hydrochlorothiazide tablets are indicated for the treatment of hypertension to lower blood pressure. Lowering blood pressure lowers the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including lisinopril and hydrochlorothiazide. Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise and limited sodium intake. Many patients will require more than one drug to achieve blood pressure goals. For specific advice on goals and management, see published guidelines, such as those of the National High Blood Pressure Education Program’s Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (JNC). Numerous antihypertensive drugs, from a variety of pharmacologic classes and with different mechanisms of action, have been shown in randomized controlled trials to reduce cardiovascular morbidity and mortality, and it can be concluded that it is blood pressure reduction, and not some other pharmacologic property of the drugs, that is largely responsible for those benefits. The largest and most consistent cardiovascular outcome benefit has been a reduction in the risk of stroke, but reductions in myocardial infarction and cardiovascular mortality also have been seen regularly. Elevated systolic or diastolic pressure causes increased cardiovascular risk, and the absolute risk increase per mmHg is greater at higher blood pressures, so that even modest reductions of severe hypertension can provide substantial benefit. Relative risk reduction from blood pressure reduction is similar across populations with varying absolute risk, so the absolute benefit is greater in patients who are at higher risk independent of their hypertension (for example, patients with diabetes or hyperlipidemia), and such patients would be expected to benefit from more aggressive treatment to a lower blood pressure goal. Some antihypertensive drugs have smaller blood pressure effects (as monotherapy) in black patients, and many antihypertensive drugs have additional approved indications and effects (eg, on angina, heart failure or diabetic kidney disease). These considerations may guide selection of therapy. These fixed dose combinations are not indicated for initial therapy (see DOSAGE AND ADMINISTRATION). In using lisinopril and hydrochlorothiazide tablets, consideration should be given to the fact that an angiotensin-converting enzyme inhibitor, captopril, has caused agranulocytosis, particularly in patients with renal impairment or collagen vascular disease, and that available data are insufficient to show that lisinopril does not have a similar risk (see WARNINGS). In considering the use of lisinopril and hydrochlorothiazide tablets, it should be noted that ACE inhibitors have been associated with a higher rate of angioedema in black than in nonblack patients (see WARNINGS: Lisinopril).
Is using Lisinopril And Hydrochlorothiazide Lisinopril 50 Mg, Hydrochlorothiazide 50 Mg safe or dangerous while breastfeeding?
Lisinopril and Hydrochlorothiazide are the two main ingredients of Lisinopril And Hydrochlorothiazide Lisinopril 50 Mg, Hydrochlorothiazide 50 Mg. Based on our individual analysis of Lisinopril and Hydrochlorothiazide we can safely say that Lisinopril And Hydrochlorothiazide Lisinopril 50 Mg, Hydrochlorothiazide 50 Mg has low risk while breastfeeding. Below we have summarized the usage of Lisinopril and Hydrochlorothiazide while breastfeeding, we recommend you to go through it for better understanding of your usage.
Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers It is not known whether lisinopril is excreted in human milk. However, milk of lactating rats contains radioactivity following administration of 14C lisinopril. In another study, lisinopril was present in rat milk at levels similar to plasma levels in the dams. Thiazides do appear in human milk. Because of the potential for serious adverse reactions in nursing infants from ACE inhibitors and hydrochlorothiazide, a decision should be made whether to discontinue nursing and/or discontinue lisinopril and hydrochlorothiazide, taking into account the importance of the drug to the mother.
Lisinopril And Hydrochlorothiazide Lisinopril 50 Mg, Hydrochlorothiazide 50 Mg Breastfeeding Analsys
Lisinopril while Breastfeeding Low Risk
CAS Number: 76547-98-3
Higher caution on early neonatal period is required. Check-up for blood hypotension and muscular hypotonia.
Hydrochlorothiazide while Breastfeeding Safe
CAS Number: 58-93-5
Thiazide diuretic drug. Excretion into breast milk is clinically non-significant. No side-effects were observed in a one-month old breastfed baby whose mother was treated with this medication. Drug level in the plasma of this child was undetectable. Long-term treatment with diuretic drugs (particularly Thiazide type ones with long-lasting effect and loop-acting mechanism) may inhibit lactation, mostly if lactation is not well-established yet. Use as lower dose as possible, especially during the first postnatal month. American Academy of Pediatrics 2013: Maternal Medication Usually Compatible With Breastfeeding. WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.
Lisinopril And Hydrochlorothiazide Lisinopril 50 Mg, Hydrochlorothiazide 50 Mg Breastfeeding Analsys - 2
Lisinopril while Breastfeeding
CAS Number: 83915-83-7
Because no information is available on the use of lisinopril during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Hydrochlorothiazide while Breastfeeding
CAS Number: 58-93-5
Hydrochlorothiazide doses of 50 mg daily or less are acceptable during lactation. Intense diuresis with large doses may decrease breastmilk production.
I already used Lisinopril And Hydrochlorothiazide Lisinopril 50 Mg, Hydrochlorothiazide 50 Mg and meanwhile I breastfed my baby should I be concerned?
During whole lactation period you shall first discuss with your doctor and then together you shall decide whether you shall take that drug or not however if you have already taken Lisinopril And Hydrochlorothiazide Lisinopril 50 Mg, Hydrochlorothiazide 50 Mg then you shall inform your doctor, But you should not be worried too much as Lisinopril And Hydrochlorothiazide Lisinopril 50 Mg, Hydrochlorothiazide 50 Mg comes in category of low risk drug.
My doctor has prescribed me Lisinopril And Hydrochlorothiazide Lisinopril 50 Mg, Hydrochlorothiazide 50 Mg, what should I do?
Though Lisinopril And Hydrochlorothiazide Lisinopril 50 Mg, Hydrochlorothiazide 50 Mg dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.
If I am using Lisinopril And Hydrochlorothiazide Lisinopril 50 Mg, Hydrochlorothiazide 50 Mg, will my baby need extra monitoring?
Who can I talk to if I have questions about usage of Lisinopril And Hydrochlorothiazide Lisinopril 50 Mg, Hydrochlorothiazide 50 Mg in breastfeeding?
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week