Azacitidine Injection, Powder, Lyophilized, For Solution Breastfeeding
It is a well known fact that breastfeeding is best source of nutrition for infants. Breast milk provides minerals, vitamins and antibodies in most acceptable format when they need it. Nutrition taken by mother passes to breast-milk and same thing applies to medicines taken by mothers. Not all drugs cause problem for baby but some do. Lets analyze if Azacitidine Injection, Powder, Lyophilized, For Solution is safe for baby while breastfed.

What is Azacitidine Injection, Powder, Lyophilized, For Solution used for?


Azacitidine for injection is a nucleoside metabolic inhibitor indicated for the treatment of patients with the following FAB myelodysplastic syndrome (MDS) subtypes: Refractory anemia (RA) or refractory anemia with ringed sideroblasts (RARS) (if accompanied by neutropenia or thrombocytopenia or requiring transfusions), refractory anemia with excess blasts (RAEB), refractory anemia with excess blasts in transformation (RAEB-T), and chronic myelomonocytic leukemia (CMMoL). (1) 1.1 Myelodysplastic Syndromes (MDS) Azacitidine for injection is indicated for treatment of patients with the following French-American-British (FAB) myelodysplastic syndrome subtypes: refractory anemia (RA) or refractory anemia with ringed sideroblasts (if accompanied by neutropenia or thrombocytopenia or requiring transfusions), refractory anemia with excess blasts (RAEB), refractory anemia with excess blasts in transformation (RAEB-T), and chronic myelomonocytic leukemia (CMMoL).

Is Azacitidine Injection, Powder, Lyophilized, For Solution safe to use while breastfeeding? Can it interfere with growth and development of my kid?

Azacitidine Injection, Powder, Lyophilized, For Solution contains Azacitidine as active ingredients, . We do not have safety rating of Azacitidine but we do have analysis of Azacitidine, which is used in manufacturing of Azacitidine Injection, Powder, Lyophilized, For Solution. You can get a good idea about Azacitidine Injection, Powder, Lyophilized, For Solution usage while breastfeeding by going through our detailed analysis as below.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Females and Males of Reproductive Potential Based on its mechanism of action and findings in animals, Azacitidine can cause fetal harm when administered to a pregnant woman [ see Use in Specific Populations (8.1) ]. Pregnancy Testing Verify the pregnancy status of females of reproductive potential prior to initiating azacitidine. Contraception Females Advise females of reproductive potential to avoid pregnancy during treatment with azacitidine. Males Males with female sexual partners of reproductive potential should not father a child and should use effective contraception during treatment with azacitidine. Infertility Based on animal data, azacitidine could have an effect on male or female fertility [ see Nonclinical Toxicology (13.1) ].

Azacitidine Injection, Powder, Lyophilized, For Solution Breastfeeding Analsys


Azacitidine while Breastfeeding

CAS Number: 320-67-2

Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy. It might be possible to breastfeed safely during intermittent azacitidine therapy with an appropriate period of breastfeeding abstinence; the manufacturer recommends an abstinence period of 1 week after the last dose. Chemotherapy may adversely affect the normal microbiome and chemical makeup of breastmilk.[1] Women who receive chemotherapy during pregnancy are more likely to have difficulty nursing their infant.[2]

Azacitidine Injection, Powder, Lyophilized, For Solution and breastfeeding

What should I do if already breastfed my kid after using Azacitidine Injection, Powder, Lyophilized, For Solution?

We are not completely sure about safety of Azacitidine Injection, Powder, Lyophilized, For Solution in breastfeeding. We would suggest you to contact your doctor or health care provider and explain your situation with Azacitidine Injection, Powder, Lyophilized, For Solution. If you observe anything abnormal with your baby please call 911 or contact emergency services in your area.


My health care provider has asked me to use Azacitidine Injection, Powder, Lyophilized, For Solution, what to do?

If your doctor considers Azacitidine Injection, Powder, Lyophilized, For Solution safe enough to prescribe for you that means its benefits outweigh its known risks.


If I am using Azacitidine Injection, Powder, Lyophilized, For Solution, will my baby need extra monitoring?

Not Sure, Please check with your doctor or lactation consultant.


Who can I talk to if I have questions about usage of Azacitidine Injection, Powder, Lyophilized, For Solution in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week

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