Trientine Hydrochloride Capsule Breastfeeding
Nutrients from the food that you eat passes to your breast milk. Its good idea to take healthy diet while breastfeeding. You may need to consume more calories per day to support healthy body system. Some time it gets necessary take medicine while you are breastfeeding and as other food items passes into breast milk, medicine passes as well hence it becomes obvious to understand its effects while breastfeeding. We have analyzed many medications and in this sheet we will present some fact and known information associated with Trientine Hydrochloride Capsule while breast-feeding.

What is Trientine Hydrochloride Capsule used for?


Trientine hydrochloride capsules are indicated in the treatment of patients with Wilson's disease who are intolerant of penicillamine. Clinical experience with trientine hydrochloride capsules is limited and alternate dosing regimens have not been well-characterized; all endpoints in determining an individual patient's dose have not been well defmed. Trientine hydrochloride capsules and penicillamine cannot be considered interchangeable. Trientine hydrochloride capsules should be used when continued treatment with penicillamine is no longer possible because of intolerable or life endangering side effects. Unlike penicillamine, trientine hydrochloride capsules are not recommended in cystinuria or rheumatoid arthritis. The absence of a sulfhydryl moiety renders it incapable of binding cystine and, therefore, it is of no use in cystinuria. In 15 patients with rheumatoid arthritis, trientine hydrochloride capsules was reported not to be effective in improving any clinical or biochemical parameter after 12 weeks of treatment. Trientine hydrochloride capsules are not indicated for treatment of biliary cirrhosis.

Trientine Hydrochloride Capsule while breastfeeding safe or not? Can there be any side effects for infant while using it during breastfeeding?

Trientine Hydrochloride Capsule low risk for breastfeeding
Trientine Hydrochloride Capsule contains only one active ingredient that is Trientine hydrochloride. We have analyzed the usage of Trientine hydrochloride in breastfeeding and our analysis suggest that Trientine hydrochloride poses Low risk for infant while breastfeeding and hence Trientine Hydrochloride Capsule itself shall be considered Low risk item for breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when trientine hydrochloride is administered to a nursing mother.

Trientine Hydrochloride Capsule Breastfeeding Analsys


Trientine hydrochloride while Breastfeeding

Low Risk

CAS Number: 112-24-3

Copper chelator used in the treatment of Wilson's disease. It is excreted in breast milk in clinically insignificant amounts (undetectable levels: Izumi 2012). Copper and zinc levels in breastmilk of mothers treated with penicillamine, trientine or zinc are normal (Izumi 2012). Oral bioavailability, which is very low during periods of fasting, is practically non-existent in the presence of food, especially milk, so it would be very difficult to pass into the infant plasma from the ingested breast milk (PDR 2016).

Trientine Hydrochloride Capsule Breastfeeding Analsys - 2


Trientine hydrochloride while Breastfeeding

CAS Number: 112-24-3

Limited information indicates that trientine is not detectable in breastmilk. The effect of trientine on breastmilk copper and zinc concentrations in milk is conflicting,[1][2][3] but breastfed infants appear to have normal serum copper and zinc plasma levels. Based on available data, it appears that trientine is acceptable to use during breastfeeding.


I am nursing mother and I have already used Trientine Hydrochloride Capsule, what should I do?

During whole lactation period you shall first discuss with your doctor and then together you shall decide whether you shall take that drug or not however if you have already taken Trientine Hydrochloride Capsule then you shall inform your doctor, But you should not be worried too much as Trientine Hydrochloride Capsule comes in category of low risk drug.


I am nursing mother and my doctor has suggested me to use Trientine Hydrochloride Capsule, is it safe?

Trientine Hydrochloride Capsule comes in category of low risk and if your doctor is aware that you are breastfeeding it should be ok to use without much concerns.


If I am using Trientine Hydrochloride Capsule, will my baby need extra monitoring?

Not much


Who can I talk to if I have questions about usage of Trientine Hydrochloride Capsule in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week

Drug Brands with same Active ingredients

Trientine Hydrochloride | Trientine Capsule, Gelatin Coated