Trientine Hydrochloride 250 Mg Breastfeeding

It is a well known fact that breastfeeding is best source of nutrition for infants. Breast milk provides minerals, vitamins and antibodies in most acceptable format when they need it. Nutrition taken by mother passes to breast-milk and same thing applies to medicines taken by mothers. Not all drugs cause problem for baby but some do. Lets analyze if Trientine Hydrochloride 250 Mg is safe for baby while breastfed.

What is Trientine Hydrochloride 250 Mg used for?

Trientine hydrochloride capsules USP 250 mg is indicated in the treatment of patients with Wilson's disease who are intolerant of penicillamine. Clinical experience with trientine hydrochloride capsules USP 250 mg is limited and alternate dosing regimens have not been well-characterized; all endpoints in determining an individual patient's dose have not been well defined. Trientine hydrochloride capsules USP 250 mg and penicillamine cannot be considered interchangeable. Trientine hydrochloride capsules USP 250 mg should be used when continued treatment with penicillamine is no longer possible because of intolerable or life endangering side effects. Unlike penicillamine, trientine hydrochloride capsules USP 250 mg is not recommended in cystinuria or rheumatoid arthritis. The absence ofa sulfhydryl moiety renders it incapable of binding cystine and, therefore, it is of no use in cystinuria. In 15 patients with rheumatoid arthritis, trientine hydrochloride capsules USP 250 mg was reported not to be effective in improving any clinical or biochemical parameter after 12 weeks of treatment. Trientine hydrochloride capsules USP 250 mg is not indicated for treatment of biliary cirrhosis.

I am breastfeeding mother and I am using Trientine Hydrochloride 250 Mg. Can it have any bad effect on my kid? Shall I search for better alternative?

Trientine Hydrochloride 250 Mg low risk for breastfeeding
Trientine Hydrochloride 250 Mg contains only one active ingredient that is Trientine hydrochloride. We have analyzed the usage of Trientine hydrochloride in breastfeeding and our analysis suggest that Trientine hydrochloride poses Low risk for infant while breastfeeding and hence Trientine Hydrochloride 250 Mg itself shall be considered Low risk item for breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing mothers It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when trientine hydrochloride is administered to a nursing mother.

Trientine Hydrochloride 250 Mg Breastfeeding Analsys

Trientine hydrochloride while Breastfeeding

Low Risk

CAS Number: 112-24-3

Copper chelator used in the treatment of Wilson's disease. It is excreted in breast milk in clinically insignificant amounts (undetectable levels: Izumi 2012). Copper and zinc levels in breastmilk of mothers treated with penicillamine, trientine or zinc are normal (Izumi 2012). Oral bioavailability, which is very low during periods of fasting, is practically non-existent in the presence of food, especially milk, so it would be very difficult to pass into the infant plasma from the ingested breast milk (PDR 2016).

Trientine Hydrochloride 250 Mg Breastfeeding Analsys - 2

Trientine hydrochloride while Breastfeeding

CAS Number: 112-24-3

Limited information indicates that trientine is not detectable in breastmilk. The effect of trientine on breastmilk copper and zinc concentrations in milk is conflicting,[1][2][3] but breastfed infants appear to have normal serum copper and zinc plasma levels. Based on available data, it appears that trientine is acceptable to use during breastfeeding.

Is Trientine Hydrochloride 250 Mg safe while breastfeeding

What should I do if already breastfed my kid after using Trientine Hydrochloride 250 Mg?

During whole lactation period you shall first discuss with your doctor and then together you shall decide whether you shall take that drug or not however if you have already taken Trientine Hydrochloride 250 Mg then you shall inform your doctor, But you should not be worried too much as Trientine Hydrochloride 250 Mg comes in category of low risk drug.

I am nursing mother and my doctor has suggested me to use Trientine Hydrochloride 250 Mg, is it safe?

Though Trientine Hydrochloride 250 Mg dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.

If I am using Trientine Hydrochloride 250 Mg, will my baby need extra monitoring?

Not much

Who can I talk to if I have questions about usage of Trientine Hydrochloride 250 Mg in breastfeeding?

National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week