Trientine Hydrochloride | Dr.reddys Laboratories Inc Breastfeeding
American Academy of Pediatrics and other medical experts exclusively recommend to breastfeed the baby for first 6 months. Once you introduce baby to other foods it is recommended to breastfeed for at least first year of babys life. Taking medication while breastfeeding could be tricky as most drugs pass in breast milk. In this article we will evaluate Trientine Hydrochloride | Dr.reddys Laboratories Inc for its safety in breastfeeding.

What is Trientine Hydrochloride | Dr.reddys Laboratories Inc used for?


Trientine hydrochloride capsules are indicated in the treatment of patients with Wilson's disease who are intolerant of penicillamine. Clinical experience with trientine hydrochloride is limited and alternate dosing regimens have not been well-characterized; all endpoints in determining an individual patient's dose have not been well defined. Trientine hydrochloride and penicillamine cannot be considered interchangeable. Trientine hydrochloride capsules should be used when continued treatment with penicillamine is no longer possible because of intolerable or life endangering side effects. Unlike penicillamine, trientine hydrochloride capsules are not recommended in cystinuria or rheumatoid arthritis. The absence of a sulfhydryl moiety renders it incapable of binding cystine and, therefore, it is of no use in cystinuria. In 15 patients with rheumatoid arthritis, trientine hydrochloride was reported not to be effective in improving any clinical or biochemical parameter after 12 weeks of treatment. Trientine hydrochloride capsules are not indicated for treatment of biliary cirrhosis.

Is using Trientine Hydrochloride | Dr.reddys Laboratories Inc unsafe in breastfeeding? Can there be bad consequences for baby if I use it while breastfeeding?

Trientine Hydrochloride | Dr.reddys Laboratories Inc low risk for breastfeeding
Trientine hydrochloride is the one and only active ingredient present in Trientine Hydrochloride | Dr.reddys Laboratories Inc. Trientine hydrochloride in itself is a low risk drug for lactation so it is easy to understand that Trientine Hydrochloride | Dr.reddys Laboratories Inc also comes in category of Low Risk item while breastfeeding. Below is the summary of Trientine hydrochloride in breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when trientine hydrochloride capsules are administered to a nursing mother.

Trientine Hydrochloride | Dr.reddys Laboratories Inc Breastfeeding Analsys


Trientine hydrochloride while Breastfeeding

Low Risk

CAS Number: 112-24-3

Copper chelator used in the treatment of Wilson's disease. It is excreted in breast milk in clinically insignificant amounts (undetectable levels: Izumi 2012). Copper and zinc levels in breastmilk of mothers treated with penicillamine, trientine or zinc are normal (Izumi 2012). Oral bioavailability, which is very low during periods of fasting, is practically non-existent in the presence of food, especially milk, so it would be very difficult to pass into the infant plasma from the ingested breast milk (PDR 2016).


Trientine Hydrochloride | Dr.reddys Laboratories Inc Breastfeeding Analsys - 2


Trientine hydrochloride while Breastfeeding

CAS Number: 112-24-3

Limited information indicates that trientine is not detectable in breastmilk. The effect of trientine on breastmilk copper and zinc concentrations in milk is conflicting,[1][2][3] but breastfed infants appear to have normal serum copper and zinc plasma levels. Based on available data, it appears that trientine is acceptable to use during breastfeeding.



I already used Trientine Hydrochloride | Dr.reddys Laboratories Inc and meanwhile I breastfed my baby should I be concerned?

During whole lactation period you shall first discuss with your doctor and then together you shall decide whether you shall take that drug or not however if you have already taken Trientine Hydrochloride | Dr.reddys Laboratories Inc then you shall inform your doctor, But you should not be worried too much as Trientine Hydrochloride | Dr.reddys Laboratories Inc comes in category of low risk drug.


My health care provider has asked me to use Trientine Hydrochloride | Dr.reddys Laboratories Inc, what to do?

Though Trientine Hydrochloride | Dr.reddys Laboratories Inc dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.


If I am using Trientine Hydrochloride | Dr.reddys Laboratories Inc, will my baby need extra monitoring?

Not much


Who can I talk to if I have questions about usage of Trientine Hydrochloride | Dr.reddys Laboratories Inc in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week