CAS Number: 93413-62-8
It is a reuptake-inhibitor of Serotonin and Norepinephrine, and active metabolite of Venlafaxine. It is excreted in low amount into breast milk. The amount detected in the infant's plasma is in the range of 2% - 6% respective to the amount found in the mother's plasma that is considered to be much lower than that found when the mother takes Venlafaxine. Not relevant side-effects have been found in such infants.
CAS Number: 93413-62-8
Modest doses of desvenlafaxine are excreted into breastmilk, but serum drug levels of breastfed infants are less than 10% of simultaneous maternal levels. Total drug exposure of breastfed infants is about half of that experienced by breastfed infants whose mothers are taking venlafaxine.[1] Breastfed infants, especially newborn or preterm infants, should be monitored for excessive sedation and adequate weight gain if this drug is used during lactation, possibly including measurement of serum levels to rule out toxicity if there is a concern. With the related drug venlafaxine, newborn infants of mothers who took the drug during pregnancy sometimes experienced poor neonatal adaptation as seen with other antidepressants such as SSRIs or SNRIs. Similar effects may occur with desvenlafaxine.
It is always a good idea to keep your healthcare provider or doctor informed about your drug usage during pregnancy and breastfeeding but if you have not informed your doctor about Desvenlafaxine Succinate Tablet, Extended Release and have used it then do not panic as Desvenlafaxine Succinate Tablet, Extended Release is mostly safe in breastfeeding and should not cause any harm to your baby.
Definitely, Desvenlafaxine Succinate Tablet, Extended Release is safe in lactation for baby. No wonder your doctor has recommended it.
No extra baby monitoring required while mother is using Desvenlafaxine Succinate Tablet, Extended Release
US
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