It is a well known fact that breastfeeding is best source of nutrition for infants. Breast milk provides minerals, vitamins and antibodies in most acceptable format when they need it. Nutrition taken by mother passes to breast-milk and same thing applies to medicines taken by mothers. Not all drugs cause problem for baby but some do. Lets analyze if Desvenlafaxine 25 Mg is safe for baby while breastfed.
What is Desvenlafaxine 25 Mg used for?
Desvenlafaxine extended-release tablets are indicated for the treatment of adults with major depressive disorder (MDD) [see Clinical Studies (14)]. Desvenlafaxine extended-release tablets are a serotonin and norepinephrine reuptake inhibitor (SNRI) indicated for the treatment of adults with major depressive disorder (MDD) (1).
Is Desvenlafaxine 25 Mg usage safe while breastfeeding? If a lactating mother is using it can there be any effect on growth or development of infant?
Desvenlafaxine is the only one ingredient used in manufacturing of Desvenlafaxine 25 Mg, Which makes it easier to analyze its effect in breastfeeding. As per our analysis of Desvenlafaxine it is safe to use Desvenlafaxine 25 Mg while lactating. We suggest you to check further details below about Desvenlafaxine usage in breastfeeding.
Statement of Manufacturer/Labeler about breastfeeding usage
8.2 Lactation Risk Summary Available limited data from published literature show low levels of desvenlafaxine in human milk, and have not shown adverse reactions in breastfed infants (see Data). There are no data on the effects of desvenlafaxine on milk production. The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for desvenlafaxine extended-release tablets and any potential adverse effects on the breastfed child from desvenlafaxine extended-release tablets or from the underlying maternal condition. Data A lactation study was conducted in 10 breastfeeding women (at a mean of 4.3 months postpartum) who were being treated with a 50 to 150 mg daily dose of desvenlafaxine for postpartum depression. Sampling was performed at steady state (up to 8 samples) over a 24 hour dosing period, and included foremilk and hindmilk. The mean relative infant dose was calculated to be 6.8% (range of 5.5 to 8.1%). No adverse reactions were seen in the infants.
Desvenlafaxine 25 Mg Breastfeeding Analsys
Desvenlafaxine while Breastfeeding Safe
CAS Number: 93413-62-8
It is a reuptake-inhibitor of Serotonin and Norepinephrine, and active metabolite of Venlafaxine. It is excreted in low amount into breast milk. The amount detected in the infant's plasma is in the range of 2% - 6% respective to the amount found in the mother's plasma that is considered to be much lower than that found when the mother takes Venlafaxine. Not relevant side-effects have been found in such infants.
Desvenlafaxine 25 Mg Breastfeeding Analsys - 2
Desvenlafaxine while Breastfeeding
CAS Number: 93413-62-8
Modest doses of desvenlafaxine are excreted into breastmilk, but serum drug levels of breastfed infants are less than 10% of simultaneous maternal levels. Total drug exposure of breastfed infants is about half of that experienced by breastfed infants whose mothers are taking venlafaxine. Breastfed infants, especially newborn or preterm infants, should be monitored for excessive sedation and adequate weight gain if this drug is used during lactation, possibly including measurement of serum levels to rule out toxicity if there is a concern. With the related drug venlafaxine, newborn infants of mothers who took the drug during pregnancy sometimes experienced poor neonatal adaptation as seen with other antidepressants such as SSRIs or SNRIs. Similar effects may occur with desvenlafaxine.
What should I do if already breastfed my kid after using Desvenlafaxine 25 Mg?
It is always a good idea to keep your healthcare provider or doctor informed about your drug usage during pregnancy and breastfeeding but if you have not informed your doctor about Desvenlafaxine 25 Mg and have used it then do not panic as Desvenlafaxine 25 Mg is mostly safe in breastfeeding and should not cause any harm to your baby.
I am nursing mother and my doctor has suggested me to use Desvenlafaxine 25 Mg, is it safe?
Definitely, Desvenlafaxine 25 Mg is safe in lactation for baby. No wonder your doctor has recommended it.
If I am using Desvenlafaxine 25 Mg, will my baby need extra monitoring?
No extra baby monitoring required while mother is using Desvenlafaxine 25 Mg
Who can I talk to if I have questions about usage of Desvenlafaxine 25 Mg in breastfeeding?
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week