Methadone Hydrochloride | Direct_rx Breastfeeding

Do you know that important immune protective proteins are present in breast milk? Breast milk also contains required vitamins, minerals, saturated and un saturated fats. These things are extremely important for development of healthy brain. If you are taking any medicine for short term or for the chronic reason then that passes in breast milk as well, that is why you should always check the drug with your health care provider. Here at DrLact we try to analyze drugs based on available researches and in this sheet we will present our analysis for Methadone Hydrochloride | Direct_rx.

What is Methadone Hydrochloride | Direct_rx used for?

Methadone hydrochloride tablets are indicated for the: • Management of pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate. Limitations of Use • Because of the risks of addiction, abuse, and misuse with opioids, even at recommended doses, and because of the greater risks of overdose and death with long-acting opioids, reserve methadone hydrochloride tablets for use in patients for whom alternative analgesic treatment options (e.g., non-opioid analgesics or immediate-release opioid analgesics) are ineffective, not tolerated, or would be otherwise inadequate to provide sufficient management of pain. • Methadone Hydrochloride Tablets USP are not indicated as an as-needed (prn) analgesic. • Detoxification treatment of opioid addiction (heroin or other morphine-like drugs). • Maintenance treatment of opioid addiction (heroin or other morphine-like drugs), in conjunction with appropriate social and medical services. Conditions For Distribution And Use Of Methadone Products For The Treatment Of Opioid Addiction Code of Federal Regulations, Title 42, Sec 8 Methadone products when used for the treatment of opioid addiction in detoxification or maintenance programs, shall be dispensed only by opioid treatment programs (and agencies, practitioners or institutions by formal agreement with the program sponsor) certified by the Substance Abuse and Mental Health Services Administration and approved by the designated state authority. Certified treatment programs shall dispense and use methadone in oral form only and according to the treatment requirements stipulated in the Federal Opioid Treatment Standards (42 CFR 8.12). See below for important regulatory exceptions to the general requirement for certification to provide opioid agonist treatment. Failure to abide by the requirements in these regulations may result in criminal prosecution, seizure of the drug supply, revocation of the program approval, and injunction precluding operation of the program. Regulatory Exceptions To The General Requirement For Certification To Provide Opioid Agonist Treatment: During inpatient care, when the patient was admitted for any condition other than concurrent opioid addiction (pursuant to 21CFR 1306.07(c)), to facilitate the treatment of the primary admitting diagnosis). During an emergency period of no longer than 3 days while definitive care for the addiction is being sought in an appropriately licensed facility (pursuant to 21CFR 1306.07(b)).

Methadone Hydrochloride | Direct_rx while breastfeeding safe or not? Can there be any side effects for infant while using it during breastfeeding?

Methadone Hydrochloride | Direct_rx safe for breastfeeding
Active ingredient in Methadone Hydrochloride | Direct_rx is Methadone hydrochloride and based on our analysis of Methadone hydrochloride it appears that using Methadone Hydrochloride | Direct_rx is safe in breastfeeding. Below is analysis of Methadone hydrochloride while breastfeeding.

Methadone Hydrochloride | Direct_rx Breastfeeding Analsys

Methadone hydrochloride while Breastfeeding


CAS Number: 1095-90-5

Drugs used in the treatment of opioid dependence and treatment of neonatal opiate withdrawal. It is excreted in breast milk in clinically non-significant amount without problems in the short or long term in infants whose mothers were treated. Plasma levels of these infants were undetectable or very low. The dose that gets the infant through the mother's milk, even when taking 70-150 mg a-day, is much lower than that used to treat neonatal abstinence syndrome. This is a reason for not using it as a solely measure of treatment. It should be reinforced that it is observed a non-polydrug behavior and adequacy of maternal care is maintained. Many newborns are either premature or underweight infants, and over 60% develop withdrawal syndrome at about one post-natal month. Breastfeeding with regard to the entire context of addictive behavior is neither easy nor frequently achieved. Much help is needed on supporting addicted mothers by health and social services in the community. Methadone excretion into breast milk is minimal regardless of the dose taken by the mother. No correlation was found between maternal dose and concentration in either breast milk or infant plasma.It has been shown delayed onset of neonatal abstinence syndrome, less need for drug treatment and lower average of hospital stay in breastfed infants.High doses can lead to a slow start (within 2-6 weeks) of withdrawal syndrome when breastfeeding is suddenly stopped. Methadone can cause galactorrhea due to increased prolactin secretion.

Methadone Hydrochloride | Direct_rx Breastfeeding Analsys - 2

Methadone hydrochloride while Breastfeeding

CAS Number: 76-99-3

Most infants receive an estimated dose of methadone ranging from 1 to 3% of the mother's weight-adjusted methadone dosage with a few receiving 5 to 6%, which is less than the dosage used for treating neonatal abstinence. Initiation of methadone postpartum, or increasing the maternal dosage to greater than 100 mg daily therapeutically or by abuse while breastfeeding poses a risk of sedation and respiratory depression in the breastfed infant, especially if the infant was not exposed to methadone in utero. If the baby shows signs of increased sleepiness (more than usual), breathing difficulties, or limpness, a physician should be contacted immediately. Other agents are preferred over methadone for pain control during breastfeeding. Women who received methadone maintenance during pregnancy and are stable should be encouraged to breastfeed their infants postpartum, unless there is another contraindication, such as use of street drugs.[1][2][3][4][5][6][7][8][9][10] Breastfeeding may decrease, but not eliminate, neonatal withdrawal symptoms in infants who were exposed in utero. Some studies have found shorter hospital stays, durations of neonatal abstinence therapy and shorter durations of therapy among breastfed infants, although the dosage of opiates used for neonatal abstinence may not be reduced.[8][9][11][12][13][14][15][16][17] The long-term outcome of infants breastfed during maternal methadone therapy for opiate abuse has not been well studied.[18] Abrupt weaning of breastfed infants of women on methadone maintenance might result in precipitation of or an increase in infant withdrawal symptoms, and gradual weaning is advised. The breastfeeding rate among mothers taking methadone for opiate dependency has been lower than in mothers not using methadone in some studies, but this finding appears to vary by institution, indicating that other factors may be important.

I already used Methadone Hydrochloride | Direct_rx and meanwhile I breastfed my baby should I be concerned?

As usage of Methadone Hydrochloride | Direct_rx is mostly safe while breastfeeding hence there should not be any concern. In case of any change in behavior or health of your baby you should inform your health care provider about usage of Methadone Hydrochloride | Direct_rx else no further action is required.

I am nursing mother and my doctor has suggested me to use Methadone Hydrochloride | Direct_rx, is it safe?

Usage of Methadone Hydrochloride | Direct_rx is safe for nursing mothers and baby, No worries.

If I am using Methadone Hydrochloride | Direct_rx, will my baby need extra monitoring?


Who can I talk to if I have questions about usage of Methadone Hydrochloride | Direct_rx in breastfeeding?

National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week