Zonisamide | Bryant Ranch Prepack Breastfeeding
It is a well known fact that breastfeeding is best source of nutrition for infants. Breast milk provides minerals, vitamins and antibodies in most acceptable format when they need it. Nutrition taken by mother passes to breast-milk and same thing applies to medicines taken by mothers. Not all drugs cause problem for baby but some do. Lets analyze if Zonisamide | Bryant Ranch Prepack is safe for baby while breastfed.

What is Zonisamide | Bryant Ranch Prepack used for?

Zonisamide capsules USP are indicated as adjunctive therapy in the treatment of partial seizures in adults with epilepsy.

Zonisamide | Bryant Ranch Prepack while breastfeeding safe or not? Can there be any side effects for infant while using it during breastfeeding?

Zonisamide | Bryant Ranch Prepack low risk for breastfeeding
Zonisamide | Bryant Ranch Prepack contains only one active ingredient that is Zonisamide. We have analyzed the usage of Zonisamide in breastfeeding and our analysis suggest that Zonisamide poses Low risk for infant while breastfeeding and hence Zonisamide | Bryant Ranch Prepack itself shall be considered Low risk item for breastfeeding.

Zonisamide | Bryant Ranch Prepack Breastfeeding Analsys

Zonisamide while Breastfeeding

Low Risk

CAS Number: 68291-97-4

Zonisamide is excreted in breast milk in amounts that could be clinically significant, since the infant receives a relative dose well above 10% (Pack 2006, Crawford 2005, Tomson 2005, Shimoyama 1999, Kimura 1998). In spite of this high excretion in breast milk, infants who were breastfed by mothers taking zonisamide had no clinical problems (Shimoyama 1999) and their plasma zonisamide levels were only 15 to 17% of those measured in the mother (Kawada 2002, abstracts-P55 2011). Due to poor pharmacokinetics for breastfeeding with low protein binding and slow drug elimination (Jacob 2016) and the limited existing literature in relation to breastfeeding (Reimers 2014), it may be advisable to choose antiepileptics whose safety is better known (Hutchinson 2013, Davanzo 2013). If it is administered during breastfeeding, use the minimum effective dose (Reimers 2014) and monitor the infant's appetite, weight curve, psychomotor development, irritability, diarrhea, dehydration or acidosis, and it may be desirable to measure monthly plasma levels in the infant (Davanzo 2013, Pennell 2003). Some authors propose partial breastfeeding to decrease the dose that the infant receives through breast milk (Ando 2014).

Zonisamide | Bryant Ranch Prepack Breastfeeding Analsys - 2

Zonisamide while Breastfeeding

CAS Number: 68291-97-4

Limited information indicates that maternal doses of zonisamide up to 400 mg daily produce high levels in milk and infant serum, but serum levels in neonates decrease during the first month of life while nursing. Although no adverse reactions have been reported in breastfed infants, the number of infants reported have been small. Alternative drugs are preferred, but if it must be given, monitor the infant for drowsiness, adequate weight gain, and developmental milestones, especially in younger or exclusively breastfed infants and when using combinations of anticonvulsant drugs. Some clinicians recommend that mothers taking zonisamide only partially breastfeed in order to reduce the exposure of the infant to the drug and to consider monitoring infants' serum zonisamide concentrations.[1]

What should I do if already breastfed my kid after using Zonisamide | Bryant Ranch Prepack?

During whole lactation period you shall first discuss with your doctor and then together you shall decide whether you shall take that drug or not however if you have already taken Zonisamide | Bryant Ranch Prepack then you shall inform your doctor, But you should not be worried too much as Zonisamide | Bryant Ranch Prepack comes in category of low risk drug.

I am nursing mother and my doctor has suggested me to use Zonisamide | Bryant Ranch Prepack, is it safe?

Though Zonisamide | Bryant Ranch Prepack dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.

If I am using Zonisamide | Bryant Ranch Prepack, will my baby need extra monitoring?

Not much

Who can I talk to if I have questions about usage of Zonisamide | Bryant Ranch Prepack in breastfeeding?

National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week