American Academy of Pediatrics and other medical experts exclusively recommend to breastfeed the baby for first 6 months. Once you introduce baby to other foods it is recommended to breastfeed for at least first year of babys life. Taking medication while breastfeeding could be tricky as most drugs pass in breast milk. In this article we will evaluate Clonazepam | Alembic Pharmaceuticals Inc. for its safety in breastfeeding.
What is Clonazepam | Alembic Pharmaceuticals Inc. used for?
Seizure Disorders: Clonazepam orally disintegrating tablet is useful alone or as an adjunct in the treatment of the Lennox-Gastaut syndrome (petit mal variant), akinetic and myoclonic seizures. In patients with absence seizures (petit mal) who have failed to respond to succinimides, clonazepam orally disintegrating tablets may be useful. In some studies, up to 30% of patients have shown a loss of anticonvulsant activity, often within 3 months of administration. In some cases, dosage adjustment may reestablish efficacy. Panic Disorder: Clonazepam orally disintegrating tablet is indicated for the treatment of panic disorder, with or without agoraphobia, as defined in DSM-V. Panic disorder is characterized by the occurrence of unexpected panic attacks and associated concern about having additional attacks, worry about the implications or consequences of the attacks, and/or a significant change in behavior related to the attacks. The efficacy of clonazepam orally disintegrating tablets was established in two 6- to 9-week trials in panic disorder patients whose diagnoses corresponded to the DSM-IIIR category of panic disorder (see CLINICAL PHARMACOLOGY: Clinical Trials). Panic disorder (DSM-V) is characterized by recurrent unexpected panic attacks, ie, a discrete period of intense fear or discomfort in which four (or more) of the following symptoms develop abruptly and reach a peak within 10 minutes: (1) palpitations, pounding heart or accelerated heart rate; (2) sweating; (3) trembling or shaking; (4) sensations of shortness of breath or smothering; (5) feeling of choking; (6) chest pain or discomfort; (7) nausea or abdominal distress; (8) feeling dizzy, unsteady, lightheaded or faint; (9) derealization (feelings of unreality) or depersonalization (being detached from oneself); (10) fear of losing control; (11) fear of dying; (12) paresthesias (numbness or tingling sensations); (13) chills or hot flushes. The effectiveness of clonazepam orally disintegrating tablets in long-term use, that is, for more than 9 weeks, has not been systematically studied in controlled clinical trials. The physician who elects to use clonazepam orally disintegrating tablets for extended periods should periodically reevaluate the long-term usefulness of the drug for the individual patient (see DOSAGE AND ADMINISTRATION).
What are the risk associated with Clonazepam | Alembic Pharmaceuticals Inc. usage while breastfeeding? What precautions shall I take while using it in breastfeeding?
Clonazepam is the one and only active ingredient present in Clonazepam | Alembic Pharmaceuticals Inc.. Clonazepam in itself is a low risk drug for lactation so it is easy to understand that Clonazepam | Alembic Pharmaceuticals Inc. also comes in category of Low Risk item while breastfeeding. Below is the summary of Clonazepam in breastfeeding.
Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers: Mothers receiving clonazepam orally disintegrating tablets should not breastfeed their infants.
Clonazepam | Alembic Pharmaceuticals Inc. Breastfeeding Analsys
Clonazepam while Breastfeeding Low Risk
CAS Number: 1622-61-3
Intermediate-acting Benzodiazepine. Excreted in low levels into breast milk. No adverse effect on breastfed infant has been reported. However, some cases of high infant serum levels along with excessive somnolence and respiratory pauses when the mother started treatment at pregnancy were reported. Avoid use in preterm infants and early neonatal period. Whether anxiolytic rather than anticonvulsivant treatment is intended, benzodiazepines with a shorter half-life span like Lorazepam or Oxazepam should be considered. Eventual and low dose use of benzodiacepines are compatible with breastfeeding. Use the short-acting benzodiazepine and minimal effective dose as possible mostly in the neonatal period. WHO Model List of Essential Medicines (2002) rates it compatible with breastfeeding. Follow-up for sedation and feeding ability of the infant. Bed-sharing is not recommended for mothers who are taking this medication.
Clonazepam | Alembic Pharmaceuticals Inc. Breastfeeding Analsys - 2
Clonazepam while Breastfeeding
CAS Number: 1622-61-3
Maternal clonazepam occasionally causes sedation in their breastfed infants, especially when given with other central nervous system depressants. Monitor the infant for drowsiness, adequate weight gain, and developmental milestones, especially in younger, exclusively breastfed infants and when using combinations of psychotropic drugs. Monitoring of the infant's serum concentration may be indicated if excessive sedation occurs. Because it has a long half-life, a safer, shorter-acting drug should be used as rather than clonazepam. An expert consensus guideline indicates that low-dose clonazepam is an acceptable choice for refractory restless leg syndrome during lactation.
I already used Clonazepam | Alembic Pharmaceuticals Inc. and meanwhile I breastfed my baby should I be concerned?
During whole lactation period you shall first discuss with your doctor and then together you shall decide whether you shall take that drug or not however if you have already taken Clonazepam | Alembic Pharmaceuticals Inc. then you shall inform your doctor, But you should not be worried too much as Clonazepam | Alembic Pharmaceuticals Inc. comes in category of low risk drug.
My health care provider has asked me to use Clonazepam | Alembic Pharmaceuticals Inc., what to do?
Though Clonazepam | Alembic Pharmaceuticals Inc. dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.
If I am using Clonazepam | Alembic Pharmaceuticals Inc., will my baby need extra monitoring?
Who can I talk to if I have questions about usage of Clonazepam | Alembic Pharmaceuticals Inc. in breastfeeding?
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week