CAS Number: 64-86-8
It is used for treatment of Gout, Familial Mediterranean Fever. As well as for other conditions like Amyloidosis, Behçet's Syndrome, Pericarditis, Primary Biliary Cirrhosis and Pyoderma gangrenosum. It is excreted in breast milk in quantities that differ according to different published studies, from no clinically significant in some, until being important in others, but there have been no problems in infants whose mothers were treated, even after months, with undetectable plasma levels in these infants. The concomitant use of macrolide antibiotics and fruit juices (both the mother and the infant) , especially grape-fruit, is not recommended since they may interfere with bile excretion and greatly increase toxicity. The American Academy of Breastfeeding rates it as compatible with breastfeeding. List of Essential Medicines of WHO (2002): compatible with breastfeeding
CAS Number: 64-86-8
Long-term prophylactic maternal doses of colchicine up to 1.5 mg daily produce levels in milk that result in the infant receiving less than 10% of the maternal weight-adjusted dosage. The highest milk levels occur 2 to 4 hours after a dose, so avoiding breastfeeding during this time can minimize the infant dose, although some clinicians simply recommend taking the drug after nursing. No adverse effects in breastfed infants have been reported in case series and a case-control study and some authors consider colchicine safe during breastfeeding in women being treated for familial Mediterranean fever or rheumatic conditions.
During whole lactation period you shall first discuss with your doctor and then together you shall decide whether you shall take that drug or not however if you have already taken Gloperba | Colchicine Solution then you shall inform your doctor, But you should not be worried too much as Gloperba | Colchicine Solution comes in category of low risk drug.
Though Gloperba | Colchicine Solution dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.
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