CAS Number: 102767-28-2
Piracetam analog with nootropic and anti-epileptic effect. Authorized for use in children in Europe. Excreted into breast milk but infant serum levels were shown to be low. No other side effect than one case of hypotonia in a 7 days old premature whose mother was also on anti-epileptic medication. Seizures along with neonatal abstinence syndrome in a botlle fed neonate whose mother had taken Levetiracetam and Phenobarbital in pregnancy ocurred. Symptoms disappeared after initiation of breastfeeding.
CAS Number: 102767-28-2
Maternal doses of levetiracetam up to 3500 mg daily produce low levels in milk and would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. If levetiracetam is required by the mother, it is not a reason to discontinue breastfeeding. However, the infant should be monitored for drowsiness, adequate weight gain, and developmental milestones, especially in younger, exclusively breastfed infants and when using combinations of anticonvulsants. Maternal serum level monitoring and dosage adjustment is advisable in the early postpartum period if the drug was taken throughout pregnancy and breastfeeding.[1] Some evidence suggests that levetiracetam might reduce the maternal breastmilk supply in some women.
As usage of Levetiracetam Tablet, Extended Release is mostly safe while breastfeeding hence there should not be any concern. In case of any change in behavior or health of your baby you should inform your health care provider about usage of Levetiracetam Tablet, Extended Release else no further action is required.
Definitely, Levetiracetam Tablet, Extended Release is safe in lactation for baby. No wonder your doctor has recommended it.
No extra baby monitoring required while mother is using Levetiracetam Tablet, Extended Release
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