Rosuvastatin Calcium | Preferred Pharmaceuticals Inc. Breastfeeding

Do you know that important immune protective proteins are present in breast milk? Breast milk also contains required vitamins, minerals, saturated and un saturated fats. These things are extremely important for development of healthy brain. If you are taking any medicine for short term or for the chronic reason then that passes in breast milk as well, that is why you should always check the drug with your health care provider. Here at DrLact we try to analyze drugs based on available researches and in this sheet we will present our analysis for Rosuvastatin Calcium | Preferred Pharmaceuticals Inc..

What is Rosuvastatin Calcium | Preferred Pharmaceuticals Inc. used for?


Pediatric use information for patients 7 to 17 years of age is approved for AstraZeneca’s CRESTOR (rosuvastatin calcium) tablets. However, due to AstraZeneca’s marketing exclusivity rights, this drug product is not labeled with that pediatric information. Rosuvastatin calcium tablet is a HMG Co-A reductase inhibitor indicated for: •adult patients with hypertriglyceridemia as an adjunct to diet (1.3) •adult patients with primary dysbetalipoproteinemia (Type III hyperlipoproteinemia) as an adjunct to diet (1.4) •adult patients with homozygous familial hypercholesterolemia (HoFH) to reduce LDL-C, total-C, and ApoB (1.5) Limitations of use ( 1.8 ): Rosuvastatin calcium tablets have not been studied in Fredrickson Type I and V dyslipidemias. 1.3 Hypertriglyceridemia Rosuvastatin calcium tablets are indicated as adjunctive therapy to diet for the treatment of adult patients with hypertriglyceridemia. 1.4 Primary Dysbetalipoproteinemia (Type III Hyperlipoproteinemia) Rosuvastatin calcium tablets are indicated as an adjunct to diet for the treatment of adult patients with primary dysbetalipoproteinemia (Type III Hyperlipoproteinemia). 1.5 Adult Patients with Homozygous Familial Hypercholesterolemia Rosuvastatin calcium tablets are indicated as adjunctive therapy to other lipid-lowering treatments (e.g., LDL apheresis) or alone if such treatments are unavailable to reduce LDL-C, Total-C, and ApoB in adult patients with homozygous familial hypercholesterolemia. 1.8 Limitations of Use Rosuvastatin calcium tablets have not been studied in Fredrickson Type I and V dyslipidemias.

Is Rosuvastatin Calcium | Preferred Pharmaceuticals Inc. safe to use while breastfeeding? Can it interfere with growth and development of my kid?

Rosuvastatin Calcium | Preferred Pharmaceuticals Inc. high risk while breastfeeding
As Rosuvastatin Calcium | Preferred Pharmaceuticals Inc. is made of only Rosuvastatin, and Rosuvastatin is unsafe to use in breastfeeding we can safely reach on conclusion that Rosuvastatin Calcium | Preferred Pharmaceuticals Inc. is also unsafe to use while breastfeeding. Below is detailed analysis of Rosuvastatin and Rosuvastatin Calcium | Preferred Pharmaceuticals Inc. during location. We recommend you to go through provided detailed analysis as below take decision accordingly. We also recommend you talk to your health care provider before making final decision.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Females and Males of Reproductive Potential Contraception Rosuvastatin calcium may cause fetal harm when administered to a pregnant woman [see Use in Specific Populations (8.1)]. Advise females of reproductive potential to use effectivecontraception during treatment with rosuvastatin calcium.

Rosuvastatin Calcium | Preferred Pharmaceuticals Inc. Breastfeeding Analsys


Rosuvastatin while Breastfeeding

Unsafe

CAS Number: 147098-20-2

Statin pharmacologically acts by inhibiting cholesterol synthesis. Excretion into breast milk is non-significant. Its low oral biodisponibility makes absorption by the infant unlikely. Influence on alteration of breast milk fat composition is unknown. High amount of cholesterol is required by the infant to ensure appropriate development of nervous system, cell membranes and hormones or vitamin production. Avoiding use while exclusive breastfeeding would be advisable. Atorvastatin is probably safer because of a higher molecular weight that would interfer with excretion into breast milk. Pravastatin has also shown a low excretion. Simvastatin has the lowest oral biodisponibility. Interruption of drug hypercholesterolemia treatment while breastfeeding would probably not affect long-term outcome of the disease. A hypolipidemic diet should be followed.

Rosuvastatin Calcium | Preferred Pharmaceuticals Inc. Breastfeeding Analsys - 2


Rosuvastatin while Breastfeeding

CAS Number: 287714-41-4

Levels of rosuvastatin in milk are low, but no relevant published information exists with its use during breastfeeding. The consensus opinion is that women taking a statin should not breastfeed because of a concern with disruption of infant lipid metabolism. However, others have argued that children homozygous for familial hypercholesterolemia are treated with statins beginning at 1 year of age, that statins have low oral bioavailability, and risks to the breastfed infant are low, especially with rosuvastatin and pravastatin.[1] Until more data become available, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.


I already used Rosuvastatin Calcium | Preferred Pharmaceuticals Inc. and meanwhile I breastfed my baby should I be concerned?

If you observer abnormal behavior or any other health issue in infant then you should immediately call 911 or contact other contact other emergency service provider in your area otherwise closely monitor the baby and inform your doctor about your Rosuvastatin Calcium | Preferred Pharmaceuticals Inc. usage and time interval of breastfeeding.


My health care provider has asked me to use Rosuvastatin Calcium | Preferred Pharmaceuticals Inc., what to do?

If your doctor knows that you are breastfeeding mother and still prescribes Rosuvastatin Calcium | Preferred Pharmaceuticals Inc. then there must be good reason for that as Rosuvastatin Calcium | Preferred Pharmaceuticals Inc. is considered unsafe, It usually happens when doctor finds that overall advantage of taking outweighs the overall risk.


If I am using Rosuvastatin Calcium | Preferred Pharmaceuticals Inc., will my baby need extra monitoring?

Yes, Extra monitoring is required if mother is using Rosuvastatin Calcium | Preferred Pharmaceuticals Inc. and breastfeeding as it is considered unsafe for baby.


Who can I talk to if I have questions about usage of Rosuvastatin Calcium | Preferred Pharmaceuticals Inc. in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week