For most of the drugs advantages of taking medications overweighs the potential risks however some drugs could be really dangerous for breastfed baby hence every medication shall be considered separately. In this page we will discuss about purpose of Sertraline Hydrochloride Tablet and its risk associated with lactation. We will also discuss the usage of Sertraline Hydrochloride Tablet and some common side effects associated with Sertraline Hydrochloride Tablet.
What is Sertraline Hydrochloride Tablet used for?
Major Depressive Disorder– Sertraline hydrochloride is indicated for the treatment of major depressive disorder in adults. The efficacy of sertraline hydrochloride in the treatment of a major depressive episode was established in six to eight week controlled trials of adult outpatients whose diagnoses corresponded most closely to the DSM-III category of major depressive disorder (see Clinical Trials under CLINICAL PHARMACOLOGY). A major depressive episode implies a prominent and relatively persistent depressed or dysphoric mood that usually interferes with daily functioning (nearly every day for at least 2 weeks); it should include at least 4 of the following 8 symptoms: change in appetite, change in sleep, psychomotor agitation or retardation, loss of interest in usual activities or decrease in sexual drive, increased fatigue, feelings of guilt or worthlessness, slowed thinking or impaired concentration, and a suicide attempt or suicidal ideation. The antidepressant action of sertraline hydrochloride in hospitalized depressed patients has not been adequately studied. The efficacy of sertraline hydrochloride in maintaining an antidepressant response for up to 44 weeks following 8 weeks of open-label acute treatment (52 weeks total) was demonstrated in a placebo-controlled trial. The usefulness of the drug in patients receiving sertraline hydrochloride for extended periods should be reevaluated periodically (see Clinical Trials under CLINICAL PHARMACOLOGY). Premenstrual Dysphoric Disorder (PMDD) – Sertraline hydrochloride is indicated for the treatment of premenstrual dysphoric disorder (PMDD) in adults. The efficacy of sertraline hydrochloride in the treatment of PMDD was established in 2 placebo-controlled trials of female adult outpatients treated for 3 menstrual cycles who met criteria for the DSM-IIIR/IV category of PMDD (see Clinical Trials under CLINICAL PHARMACOLOGY). The essential features of PMDD include markedly depressed mood, anxiety or tension, affective lability, and persistent anger or irritability. Other features include decreased interest in activities, difficulty concentrating, lack of energy, change in appetite or sleep, and feeling out of control. Physical symptoms associated with PMDD include breast tenderness, headache, joint and muscle pain, bloating and weight gain. These symptoms occur regularly during the luteal phase and remit within a few days following onset of menses; the disturbance markedly interferes with work or school or with usual social activities and relationships with others. In making the diagnosis, care should be taken to rule out other cyclical mood disorders that may be exacerbated by treatment with an antidepressant. The effectiveness of sertraline hydrochloride in long-term use, that is, for more than 3 menstrual cycles, has not been systematically evaluated in controlled trials. Therefore, the physician who elects to use sertraline hydrochloride for extended periods should periodically re-evaluate the long-term usefulness of the drug for the individual patient (see DOSAGE AND ADMINISTRATION).
Sertraline Hydrochloride Tablet while breastfeeding safe or not? Can there be any side effects for infant while using it during breastfeeding?
Sertraline is the only one ingredient used in manufacturing of Sertraline Hydrochloride Tablet, Which makes it easier to analyze its effect in breastfeeding. As per our analysis of Sertraline it is safe to use Sertraline Hydrochloride Tablet while lactating. We suggest you to check further details below about Sertraline usage in breastfeeding.
Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers–It is not known whether, and if so in what amount, sertraline or its metabolites are excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when sertraline hydrochloride is administered to a nursing woman.
Sertraline Hydrochloride Tablet Breastfeeding Analsys
Sertraline while Breastfeeding Safe
CAS Number: 79559-97-0
Excreted in tiny amounts into breast milk. Serum levels of breastfed infants whose mothers are on Sertraline are usually undetectable or very low. No harm effect has been observed on health and short or long term development of infants. Transient troubles in the early neonatal period like drug withdrawal syndrome among newborn or premature infants with high serum levels as a result of treatment with Sertraline to the mother during pregnancy have been observed. Sertraline causes fewer problems related to galactorrhea than other antidepressant drugs. It is probably the safest antidepressant medication while breastfeeding. Mothers who are treated with antidepressant medicaction are in need of stronger support for a higher risk of early breastfeeding failure.
Sertraline Hydrochloride Tablet Breastfeeding Analsys - 2
Sertraline while Breastfeeding
CAS Number: 79617-96-2
Because of the low levels of sertraline in breastmilk, amounts ingested by the infant are small and is usually not detected in the serum of the infant, although the weakly active metabolite norsertraline (desmethylsertraline) is often detectable in low levels in infant serum. Rarely, preterm infants with impaired metabolic activity might accumulate the drug and demonstrate symptoms similar to neonatal abstinence. Most authoritative reviewers consider sertraline a preferred antidepressants during breastfeeding. Mothers taking an SSRI during pregnancy and postpartum may have more difficulty breastfeeding, although this might be a reflection of their disease state. These mothers may need additional breastfeeding support. Breastfed infants exposed to an SSRI during the third trimester of pregnancy have a lower risk of poor neonatal adaptation than formula-fed infants.
What should I do if I am breastfeeding mother and I am already exposed to Sertraline Hydrochloride Tablet?
As usage of Sertraline Hydrochloride Tablet is mostly safe while breastfeeding hence there should not be any concern. In case of any change in behavior or health of your baby you should inform your health care provider about usage of Sertraline Hydrochloride Tablet else no further action is required.
I am nursing mother and my doctor has suggested me to use Sertraline Hydrochloride Tablet, is it safe?
Definitely, Sertraline Hydrochloride Tablet is safe in lactation for baby. No wonder your doctor has recommended it.
If I am using Sertraline Hydrochloride Tablet, will my baby need extra monitoring?
No extra baby monitoring required while mother is using Sertraline Hydrochloride Tablet
Who can I talk to if I have questions about usage of Sertraline Hydrochloride Tablet in breastfeeding?
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week