Amiodarone Hydrochloride Tablet Breastfeeding

Do you know that important immune protective proteins are present in breast milk? Breast milk also contains required vitamins, minerals, saturated and un saturated fats. These things are extremely important for development of healthy brain. If you are taking any medicine for short term or for the chronic reason then that passes in breast milk as well, that is why you should always check the drug with your health care provider. Here at DrLact we try to analyze drugs based on available researches and in this sheet we will present our analysis for Amiodarone Hydrochloride Tablet.

What is Amiodarone Hydrochloride Tablet used for?

Amiodarone hydrochloride tablets are indicated for the treatment of documented, life-threatening recurrent ventricular fibrillation and life-threatening recurrent hemodynamically unstable tachycardia in adults who have not responded to adequate doses of other available antiarrhythmics or when alternative agents cannot be tolerated. Amiodarone hydrochloride is an antiarrhythmic indicated for: Recurrent ventricular fibrillation. ( 1) Recurrent hemodynamically unstable ventricular tachycardia. ( 1)

Amiodarone Hydrochloride Tablet while breastfeeding safe or not? Can there be any side effects for infant while using it during breastfeeding?

Amiodarone Hydrochloride Tablet high risk while breastfeeding
As Amiodarone Hydrochloride Tablet is made of only Amiodarone hydrochloride, and Amiodarone hydrochloride is unsafe to use in breastfeeding we can safely reach on conclusion that Amiodarone Hydrochloride Tablet is also unsafe to use while breastfeeding. Below is detailed analysis of Amiodarone hydrochloride and Amiodarone Hydrochloride Tablet during location. We recommend you to go through provided detailed analysis as below take decision accordingly. We also recommend you talk to your health care provider before making final decision.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Females and Males of Reproductive Potential Infertility Based on animal fertility studies, amiodarone hydrochloride may reduce female and male fertility. It is not known if this effect is reversible. [see Nonclinical Toxicology (13.1)].

Amiodarone Hydrochloride Tablet Breastfeeding Analsys

Amiodarone hydrochloride while Breastfeeding


CAS Number: 1951-25-3

A published case of infant hypothyroidism. Others have reported lab controlled cases with harmless effect in breastfed babies.

Amiodarone Hydrochloride Tablet Breastfeeding Analsys - 2

Amiodarone hydrochloride while Breastfeeding

CAS Number: 1951-25-3

Breastmilk and infant serum levels of amiodarone and its active metabolite are somewhat unpredictable, but can be high during breastfeeding. The infant receives an estimated dose of amiodarone plus desethylamiodarone ranging from 3.5 to 45% of the mother's weight-adjusted amiodarone dose, with a median dose of about 11%.[1][2][3][4] Infant serum levels of the drug plus metabolite range from 14 to 74% of simultaneous maternal levels, with the higher values reflecting transplacental passage of the drug.[2][3][4] In addition to possible cardiac effects, these compounds contain a large amount of iodine which may be released during metabolism. Thyroid dysfunction was reported in one breastfed infant. Even if the drug were discontinued at birth, the mother would continue to excrete amiodarone and its metabolite (and possibly large amounts of iodine) into breastmilk for days to weeks. Some investigators believe that breastfeeding can be undertaken during maternal amiodarone use with periodic monitoring of infant cardiac and thyroid function status,[5][6] especially if only a single dose of amiodarone is given.[7] Infant serum levels of amiodarone and desethylamiodarone may be useful for ruling out cardiac effects of the drug. If hypothyroidism develops, therapy should be promptly initiated.

I already used Amiodarone Hydrochloride Tablet and meanwhile I breastfed my baby should I be concerned?

If you observer abnormal behavior or any other health issue in infant then you should immediately call 911 or contact other contact other emergency service provider in your area otherwise closely monitor the baby and inform your doctor about your Amiodarone Hydrochloride Tablet usage and time interval of breastfeeding.

I am nursing mother and my doctor has suggested me to use Amiodarone Hydrochloride Tablet, is it safe?

If your doctor knows that you are breastfeeding mother and still prescribes Amiodarone Hydrochloride Tablet then there must be good reason for that as Amiodarone Hydrochloride Tablet is considered unsafe, It usually happens when doctor finds that overall advantage of taking outweighs the overall risk.

If I am using Amiodarone Hydrochloride Tablet, will my baby need extra monitoring?

Yes, Extra monitoring is required if mother is using Amiodarone Hydrochloride Tablet and breastfeeding as it is considered unsafe for baby.

Who can I talk to if I have questions about usage of Amiodarone Hydrochloride Tablet in breastfeeding?

National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week