Clarins Uv Plus Anti-pollution Sunscreen Multi-protection Broad Spectrum Spf 50 Oil-free -deep while Breastfeeding

Our analysis of Homosalate, Octocrylene, Oxybenzone, Titanium dioxide which are active ingredients in Clarins Uv Plus Anti-pollution Sunscreen Multi-protection Broad Spectrum Spf 50 Oil-free -deep indicates that Clarins Uv Plus Anti-pollution Sunscreen Multi-protection Broad Spectrum Spf 50 Oil-free -deep is dangerous to use in breastfeeding. We strongly recommend you to go through detailed analysis of Homosalate, Octocrylene, Oxybenzone, Titanium dioxide as below and do not use Clarins Uv Plus Anti-pollution Sunscreen Multi-protection Broad Spectrum Spf 50 Oil-free -deep during breastfeeding.

Homosalate and Breastfeeding

Homosalate has been found in mothers milk, its skin penetration rate is less than 1% in human and laboratory studies. Some studies suggest that Homosalate disrupts estrogen, androgen and progesterone levels. As not much study has been done on effects of Homosalate during breast feeding its recommended to use safe alternatives.

Octocrylene and Breastfeeding

Based on the current available safety data, octocrylene used as a UV filter in cosmetic products at a concentration of 10% can be considered as safe. There was no evidence of any endocrine disruption potential from experimental studies which demonstrated no adverse effects on reproductive (e.g. oestrus cycle, epididymal and testicular sperm parameters) and developmental parameters. Effects on thyroid reported in repeated toxicity studies conducted in rats at very high doses are species?specific and not relevant considering the doses at which octocrylene is used in human.

Four studies on the transdermal absorption of octocrylene are available in the scientific literature, and an additional study is available in ECHA summaries of safety data. Dermal absorption studies of octocrylene showed that most octocrylene concentrations are found in the stratum corneum and that very few quantities are found in the epidermis (0.4%) and in the receptor fluid (<0.05%). In vivo, a very recent study in human volunteers showed systemic exposure to octocrylene with maximal concentrations ranging from 2.9 to 7.8 ng/mL under indoor maximal use conditions. Octocrylene has been found at very low amounts in human milk, and some metabolites of octocrylene were primarily detected in urine of volunteers using sunscreen products.

No systemic effects were reported after dermal exposure to octocrylene in rabbits at very high dose (534 mg/kg bw/day) compared with those used in cosmetic products. After oral exposure, effects on liver and thyroid were reported in a study conducted in rats at high doses (340 and 1085 mg/kg bw/day in males). These effects were investigated in an additional mechanistic study which showed that effects on thyroid were indirect and due to hepatic enzyme induction potential of octocrylene in rats at very high oral doses.

Based on available animal data, octocrylene does not induce developmental or teratogenic effects. In an extended one?generation reproductive toxicity study, only rats treated with the highest dose of octocrylene via oral route showed a decrease in the number of implantation sites and consequently a low number of pups. This very high dose of 550 mg/kg bw/day cannot be considered to be relevant to the dermal use of octocrylene as a cosmetic ingredient. Moreover, no other effects on male and female fertility and reproductive parameters such as oestrus cycle, epididymal and testicular sperm parameters were observed in all groups tested. Regarding pups, no effects on sexual and neurodevelopmental parameters were observed.

Oxybenzone and Breastfeeding

Oxybenzone has been found in mother�s milk. And has relatively high 1% to 9% skin penetration in lab studies. Oxybenzone has relatively high rates of skin allergy, it has weak estrogen like effects, and its observed as moderate anti-androgen. Oxybenzone is associated with altered birth weight in human studies. It is not recommended to use Oxybenzone during breast feeding.

Titanium dioxide and Breastfeeding

Not much study has been done on effects of topical usage of Titanium Dioxide during breast feeding but as there is no finding of Titanium Dioxide passing in breast milk its unlikely to cause any health issue for infant.

Some animal studies suggest that maternal exposure to titanium dioxide nanoparticles during pregnancy and lactation alters offspring hippocampal mRNA BAX and Bcl-2 levels, induces apoptosis and decreases neurogenesis. But dosage was significantly higher than daily possible exposure to humans.

I am nursing mother and I have already used Clarins Uv Plus Anti-pollution Sunscreen Multi-protection Broad Spectrum Spf 50 Oil-free -deep, what should I do?

My doctor has prescribed me Clarins Uv Plus Anti-pollution Sunscreen Multi-protection Broad Spectrum Spf 50 Oil-free -deep, what should I do?

If I am using Clarins Uv Plus Anti-pollution Sunscreen Multi-protection Broad Spectrum Spf 50 Oil-free -deep, will my baby need extra monitoring?

Who can I talk to if I have questions about usage of Clarins Uv Plus Anti-pollution Sunscreen Multi-protection Broad Spectrum Spf 50 Oil-free -deep in breastfeeding?