Losartan Potassium And Hydrochlorothiazide Tablet Breastfeeding

Most health expert recommend six month of exclusive breastfeeding but statics suggest that numbers are not good, almost 95% mothers start breastfeeding but this number drops to 40% in first three month and further it drops to 15% till fifth month. Sometime its due to need of medication usage. Because of these statics its important to provide good information on safety of drugs in breastfeeding so that it can be improved when possible. In this FAQ sheet we will discuss about exposure to Losartan Potassium And Hydrochlorothiazide Tablet while breastfeeding. We will also discuss about common side effects and warnings associated with Losartan Potassium And Hydrochlorothiazide Tablet.

Losartan potassium and hydrochlorothiazide tablets 50 mg/ 12.5 mg and losartan potassium and hydrochlorothiazide tablets 100 mg/ 25 mg combine an angiotensin II receptor (type AT1) antagonist and a diuretic, hydrochlorothiazide. Losartan potassium, a non-peptide molecule, is chemically described as 2-butyl-4-chloro-1-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]imidazole-5-methanol monopotassium salt. Its molecular formula is C22H22ClKN6O, and its structural formula is: Losartan potassium, USP is off-white to creamish-yellow powder with a molecular weight of 461.01. It is soluble in water. Oxidation of the 5-hydroxymethyl group on the imidazole ring results in the active metabolite of losartan. Hydrochlorothiazide is 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide. Its molecular formula is C7H8ClN3O4S2 and its structural formula is: Hydrochlorothiazide, USP is a white or practically white, practically odorless crystalline powder with a molecular weight of 297.74. It is slightly soluble in water; freely soluble in sodium hydroxide solution, in n-butylamine, and in dimethylformamide, sparingly soluble in methanol; insoluble in ether, in chloroform, and in dilute mineral acids. Each losartan potassium and hydrochlorothiazide tablet intended for oral administration contains losartan potassium, 50 mg or 100 mg and hydrochlorothiazide, 12.5 mg or 25 mg. In addition, each tablet also contains the following inactive ingredients: colloidal silica anhydrous, hydroxypropyl cellulose (low substituted), hydroxypropyl methylcellulose, lactose monohydrate, magnesium stearate, maize starch, microcrystalline cellulose, polyethylene glycol, sodium starch glycolate, talc and titanium dioxide. Losartan potassium and hydrochlorothiazide tablet 50 mg/ 12.5 mg contains 4.24 mg (0.108 mEq) of potassium and losartan potassium and hydrochlorothiazide tablet 100 mg/ 25 mg contains 8.48 mg (0.216 mEq) of potassium. structured formula for losartan structured formula for losartan

Is using Losartan Potassium And Hydrochlorothiazide Tablet unsafe in breastfeeding? Can there be bad consequences for baby if I use it while breastfeeding?

Losartan Potassium And Hydrochlorothiazide Tablet low risk for breastfeeding
Hydrochlorothiazide and Losartan potassium are the two main ingredients of Losartan Potassium And Hydrochlorothiazide Tablet. Based on our individual analysis of Hydrochlorothiazide and Losartan potassium we can safely say that Losartan Potassium And Hydrochlorothiazide Tablet has low risk while breastfeeding. Below we have summarized the usage of Hydrochlorothiazide and Losartan potassium while breastfeeding, we recommend you to go through it for better understanding of your usage.

Losartan Potassium And Hydrochlorothiazide Tablet Breastfeeding Analsys


Hydrochlorothiazide while Breastfeeding

Safe

CAS Number: 58-93-5

Thiazide diuretic drug. Excretion into breast milk is clinically non-significant. No side-effects were observed in a one-month old breastfed baby whose mother was treated with this medication. Drug level in the plasma of this child was undetectable. Long-term treatment with diuretic drugs (particularly Thiazide type ones with long-lasting effect and loop-acting mechanism) may inhibit lactation, mostly if lactation is not well-established yet. Use as lower dose as possible, especially during the first postnatal month. American Academy of Pediatrics 2013: Maternal Medication Usually Compatible With Breastfeeding. WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.

Losartan potassium while Breastfeeding

Low Risk

CAS Number: 124750-99-8

At latest update, relevant published data on excretion into breast milk were not found. A high protein-binding capacity makes excretion into breast milk unlikely. In addition, a low oral bioavailability makes difficult the absorption towards the infant's plasma from ingested milk, except in prematures or newborns who may show an increased absorption. Case report of kidney function impairment of a baby whose mother had taken Telmisartan in pregnancy. Until more data on this medication is available, safer alternative drugs are preferred, especially in premature babies or during the neonatal period. Should an ARA-II medication (Sartan type) be necessary, the associated risk may be decreased by choosing the one with a favorable pharmacokinetics (shorter half-life elimination time and lower bioavailability) like Eprosartan and Losartan


Losartan Potassium And Hydrochlorothiazide Tablet Breastfeeding Analsys - 2


Hydrochlorothiazide while Breastfeeding

CAS Number: 58-93-5

Hydrochlorothiazide doses of 50 mg daily or less are acceptable during lactation. Intense diuresis with large doses may decrease breastmilk production.

Losartan potassium while Breastfeeding

CAS Number: 114798-26-4

Because no information is available on the use of losartan during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.



What should I do if already breastfed my kid after using Losartan Potassium And Hydrochlorothiazide Tablet?

During whole lactation period you shall first discuss with your doctor and then together you shall decide whether you shall take that drug or not however if you have already taken Losartan Potassium And Hydrochlorothiazide Tablet then you shall inform your doctor, But you should not be worried too much as Losartan Potassium And Hydrochlorothiazide Tablet comes in category of low risk drug.


My health care provider has asked me to use Losartan Potassium And Hydrochlorothiazide Tablet, what to do?

Losartan Potassium And Hydrochlorothiazide Tablet comes in category of low risk and if your doctor is aware that you are breastfeeding it should be ok to use without much concerns.


If I am using Losartan Potassium And Hydrochlorothiazide Tablet, will my baby need extra monitoring?

Not much


Who can I talk to if I have questions about usage of Losartan Potassium And Hydrochlorothiazide Tablet in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week