Alendronate Sodium Alendronic Acid 0.5 Mg Breastfeeding

Do you know that important immune protective proteins are present in breast milk? Breast milk also contains required vitamins, minerals, saturated and un saturated fats. These things are extremely important for development of healthy brain. If you are taking any medicine for short term or for the chronic reason then that passes in breast milk as well, that is why you should always check the drug with your health care provider. Here at DrLact we try to analyze drugs based on available researches and in this sheet we will present our analysis for Alendronate Sodium Alendronic Acid 0.5 Mg.

What is Alendronate Sodium Alendronic Acid 0.5 Mg used for?


Alendronate sodium is a bisphosphonate indicated for: Treatment and prevention of osteoporosis in postmenopausal women. (1.1, 1.2) Treatment to increase bone mass in men with osteoporosis. (1.3) Treatment of glucocorticoid-induced osteoporosis. (1.4) Treatment of Paget's disease of bone. (1.5) Limitations of use: Optimal duration of use has not been determined. For patients at low-risk for fracture, consider drug discontinuation after 3 to 5 years of use. (1.6) 1.1 Treatment of Osteoporosis in Postmenopausal Women Alendronate sodium tablets are indicated for the treatment of osteoporosis in postmenopausal women. In postmenopausal women, alendronate sodium tablets increase bone mass and reduce the incidence of fractures, including those of the hip and spine (vertebral compression fractures). [See Clinical Studies (14.1).] 1.2 Prevention of Osteoporosis in Postmenopausal Women Alendronate sodium tablets are indicated for the prevention of postmenopausal osteoporosis [see Clinical Studies (14.2)]. 1.3 Treatment to Increase Bone Mass in Men with Osteoporosis Alendronate sodium tablets are indicated for treatment to increase bone mass in men with osteoporosis [see Clinical Studies (14.3)]. 1.4 Treatment of Glucocorticoid-Induced Osteoporosis Alendronate sodium tablets are indicated for the treatment of glucocorticoid-induced osteoporosis in men and women receiving glucocorticoids in a daily dosage equivalent to 7.5 mg or greater of prednisone and who have low bone mineral density [see Clinical Studies (14.4)]. 1.5 Treatment of Paget's Disease of Bone Alendronate sodium tablets are indicated for the treatment of Paget’s disease of bone in men and women. Treatment is indicated in patients with Paget's disease of bone who have alkaline phosphatase at least two times the upper limit of normal, or those who are symptomatic, or those at risk for future complications from their disease. [See Clinical Studies (14.5).] 1.6 Important Limitations of Use The optimal duration of use has not been determined. The safety and effectiveness of alendronate sodium tablets for the treatment of osteoporosis are based on clinical data of four years duration. All patients on bisphosphonate therapy should have the need for continued therapy re-evaluated on a periodic basis. Patients at low-risk for fracture should be considered for drug discontinuation after 3 to 5 years of use. Patients who discontinue therapy should have their risk for fracture re-evaluated periodically.

What are the risk associated with Alendronate Sodium Alendronic Acid 0.5 Mg usage while breastfeeding? What precautions shall I take while using it in breastfeeding?

Alendronate Sodium Alendronic Acid 0.5 Mg low risk for breastfeeding
Alendronate Sodium Alendronic Acid 0.5 Mg contains only one active ingredient that is Alendronic acid. We have analyzed the usage of Alendronic acid in breastfeeding and our analysis suggest that Alendronic acid poses Low risk for infant while breastfeeding and hence Alendronate Sodium Alendronic Acid 0.5 Mg itself shall be considered Low risk item for breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers It is not known whether alendronate is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when alendronate sodium is administered to nursing women.

Alendronate Sodium Alendronic Acid 0.5 Mg Breastfeeding Analsys


Alendronic acid while Breastfeeding

Low Risk

CAS Number: 66376-36-1

It is composed by bisphosphonates. Most bisphosphonates are acidic compounds that achieve low plasma concentration. Both features make it unlikely excretion into the milk in clinically significant amount. Alendronate has shown very low plasma concentrations (<5 ng / ml). Intestinal absorption of bisphosphonates is very low even during fasting and is considered negligible in the presence of milk due to formation with the calcium of non absorbable compounds. A latest update no published data were found on excretion in the breast milk. Until more data about this drug regarding breastfeeding is available, safer known alternatives (e.g. pamidronate) should be of choice, especially in the neonatal period and in case of prematurity.


Alendronate Sodium Alendronic Acid 0.5 Mg Breastfeeding Analsys - 2


Alendronic acid while Breastfeeding

CAS Number: 66376-36-1

Limited evidence indicates that breastfeeding after cessation of long-term bisphosphonate treatment appears to have no adverse effects on the infant. Because no information is available on the use of alendronate during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. However, absorption of alendronate by a breastfed infant is unlikely. If the mother receives a bisphosphonate during pregnancy or nursing, some experts recommend monitoring the infant's serum calcium during the first 2 months postpartum.[1]


Alendronate Sodium Alendronic Acid 0.5 Mg and breastfeeding

I already used Alendronate Sodium Alendronic Acid 0.5 Mg and meanwhile I breastfed my baby should I be concerned?

Alendronate Sodium Alendronic Acid 0.5 Mg is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Alendronate Sodium Alendronic Acid 0.5 Mg so you should inform him based on your convenience.


My health care provider has asked me to use Alendronate Sodium Alendronic Acid 0.5 Mg, what to do?

Alendronate Sodium Alendronic Acid 0.5 Mg comes in category of low risk and if your doctor is aware that you are breastfeeding it should be ok to use without much concerns.


If I am using Alendronate Sodium Alendronic Acid 0.5 Mg, will my baby need extra monitoring?

Not much monitoring required while using Alendronate Sodium Alendronic Acid 0.5 Mg


Who can I talk to if I have questions about usage of Alendronate Sodium Alendronic Acid 0.5 Mg in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week