Pl-1849 | Collapsible Sunscreen Cream while Breastfeeding
American Academy of Pediatrics and other medical experts exclusively recommend to breastfeed the baby for first 6 months. Once you introduce baby to other foods it is recommended to breastfeed for at least first year of babys life. Taking medication while breastfeeding could be tricky as most drugs pass in breast milk. In this article we will evaluate Pl-1849 | Collapsible Sunscreen Cream for its safety in breastfeeding.

What is Pl-1849 | Collapsible Sunscreen Cream used for?


Helps prevent sunburn

Brief: Sunscreen

What are the risk associated with Pl-1849 | Collapsible Sunscreen Cream usage while breastfeeding? What precautions shall I take while using it in breastfeeding?

Pl-1849 | Collapsible Sunscreen Cream dangerous while breastfeeding
Our analysis of Octinoxate, Titanium dioxide, Octisalate, Oxybenzone which are active ingredients in Pl-1849 | Collapsible Sunscreen Cream indicates that Pl-1849 | Collapsible Sunscreen Cream is dangerous to use in breastfeeding. We strongly recommend you to go through detailed analysis of Octinoxate, Titanium dioxide, Octisalate, Oxybenzone as below and do not use Pl-1849 | Collapsible Sunscreen Cream during breastfeeding.

Octinoxate and Breastfeeding

Unsafe

Octinoxate (Octylmethoxycinnamate) has been detected in human urine, blood and breast milk and is known for moderate risk of skin allergy. Some studies suggest that Octinoxate has estrogen like effects however less than 1% skin penetration has been found in human laboratory studies. As not much study has been done on effects of Octinoxate during breast feeding its recommended to use safe alternatives.

Octyl Methoxycinnamate (OMC) is a frequently used UV-filter in sunscreens and other cosmetics. Octinoxate can be systemically absorbed after skin application, being found in the deeper layers of the stratum corneum as well as urine, plasma, and breast milk. The mean maximum plasma concentration detected after application of 2mg/cm2 sunscreen was 7ng/mL in women and 16ng/mL in men. FDA study found blood levels 13 times above cutoff for systemic exposure.

Several studies indicated that OMC acts as an endocrine disruptor due to the ability to interfere with endocrine system at different levels. In humans OMC exposure has minor, but statistically significant effects on the levels of testosterone and estradiol. Moreover, some studies suggested that OMC can interact with the hypothalamo-pituitary-thyroid (HPT) axis.

Moreover, a study of offspring of dams treated with OMC (500Ė1000 mg/kg/day) showed sex-dependent behavioral changes, namely decreased motor activity in females, but not in males, and improved spatial learning in males, suggesting that OMC can affect neuronal development, however the doses used in these experiments were extremely high, not relevant to possible human exposure.

Note: Study and data for tropical use only

Warning: High dosage shall be avoided as reproductive system, thyroid and behavioral alterations in animal studies has been found, Tropical usage in breast area shall be avoided to prevent the OCTINOXATE passing orally in Infants.

Titanium dioxide and Breastfeeding

Low Risk

Not much study has been done on effects of topical usage of Titanium Dioxide during breast feeding but as there is no finding of Titanium Dioxide passing in breast milk its unlikely to cause any health issue for infant.

Some animal studies suggest that maternal exposure to titanium dioxide nanoparticles during pregnancy and lactation alters offspring hippocampal mRNA BAX and Bcl-2 levels, induces apoptosis and decreases neurogenesis. But dosage was significantly higher than daily possible exposure to humans.

Note: Study and data for tropical use only. Inhalation concerns in powder or spray products.

Warning: Tropical usage in breast area shall be avoided to prevent the Titanium Dioxide passing orally in Infants. Titanium dioxide is possibly carcinogenic to humans. Titanium dioxide can be drastically more harmful if used as powder or spray as risk of inhalation can increase significantly.

Octisalate and Breastfeeding

Low Risk

Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen. Salicylates are weak UVB absorbers and they are generally used in combination with other UV filters

Octisalate rarely causes allergies in tropical usage. Not much study has been done on effects of topical usage of Octisalate during breast feeding however it is known to penetrate the skin hence itís better to use other alternatives.

FDA study found blood levels 10 times above cutoff for systemic exposure, skin penetration in lab studies has been observed

Note: Study and data for tropical use only

Warning: Tropical usage in breast area shall be avoided to prevent the Octisalate passing orally in Infants.

Oxybenzone and Breastfeeding

Dangerous

Oxybenzone has been found in motherís milk. And has relatively high 1% to 9% skin penetration in lab studies. Oxybenzone has relatively high rates of skin allergy, it has weak estrogen like effects, and its observed as moderate anti-androgen. Oxybenzone is associated with altered birth weight in human studies. It is not recommended to use Oxybenzone during breast feeding.

Note: Study and data for tropical use only.

Warning: Tropical usage in breast area shall be avoided to prevent the Oxybenzone passing orally in Infants.


I already used Pl-1849 | Collapsible Sunscreen Cream and meanwhile I breastfed my baby should I be concerned?

You should immediately inform your health care provider about Pl-1849 | Collapsible Sunscreen Cream usage and your breastfeeding interval after usage of . If you feel baby is having abnormal behavior or any other health issue please call 911 immediately or contact nearest medical emergency center.


I am nursing mother and my doctor has suggested me to use Pl-1849 | Collapsible Sunscreen Cream, is it safe?

Please double check with your doctor if he is aware of your breastfeeding stratus, Ask your doctor if there is any safe alternative of Pl-1849 | Collapsible Sunscreen Cream. Check with your doctor if you shall temporally stop breastfeeding. You may go for second opinion as well. Still after all of this if your doctor still recommends Pl-1849 | Collapsible Sunscreen Cream then go for it as they have access on more detailed medical and scientific information and they understand your individual medical situation much better.


If I am using Pl-1849 | Collapsible Sunscreen Cream, will my baby need extra monitoring?

Extreme level of monitoring required as Pl-1849 | Collapsible Sunscreen Cream could be dangerous for kid.


Who can I talk to if I have questions about usage of Pl-1849 | Collapsible Sunscreen Cream in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week