Zometa | Zoledronic Acid Injection, Solution, Concentrate Breastfeeding
Do you know that important immune protective proteins are present in breast milk? Breast milk also contains required vitamins, minerals, saturated and un saturated fats. These things are extremely important for development of healthy brain. If you are taking any medicine for short term or for the chronic reason then that passes in breast milk as well, that is why you should always check the drug with your health care provider. Here at DrLact we try to analyze drugs based on available researches and in this sheet we will present our analysis for Zometa | Zoledronic Acid Injection, Solution, Concentrate.

What is Zometa | Zoledronic Acid Injection, Solution, Concentrate used for?


Zometa is a bisphosphonate indicated for the treatment of: Hypercalcemia of Malignancy (1.1) Patients with multiple myeloma and patients with documented bone metastases from solid tumors, in conjunction with standard antineoplastic therapy. Prostate cancer should have progressed after treatment with at least one hormonal therapy. (1.2) Limitations of Use: The safety and efficacy of Zometa has not been established for use in hyperparathyroidism or non-tumor-related hypercalcemia. 1.1 Hypercalcemia of Malignancy Zometa is indicated for the treatment of hypercalcemia of malignancy defined as an albumin-corrected calcium (cCa) of greater than or equal to 12 mg/dL [3.0 mmol/L] using the formula: cCa in mg/dL = Ca in mg/dL + 0.8 (4.0 g/dL - patient albumin [g/dL]). 1.2 Multiple Myeloma and Bone Metastases of Solid Tumors Zometa is indicated for the treatment of patients with multiple myeloma and patients with documented bone metastases from solid tumors, in conjunction with standard antineoplastic therapy. Prostate cancer should have progressed after treatment with at least one hormonal therapy. Limitations of Use The safety and efficacy of Zometa in the treatment of hypercalcemia associated with hyperparathyroidism or with other non–tumor-related conditions have not been established.

Is Zometa | Zoledronic Acid Injection, Solution, Concentrate safe to use while breastfeeding? Can it interfere with growth and development of my kid?

Zometa | Zoledronic Acid Injection, Solution, Concentrate low risk for breastfeeding
Zometa | Zoledronic Acid Injection, Solution, Concentrate contains only one active ingredient that is Zoledronic acid anhydrous. We have analyzed the usage of Zoledronic acid anhydrous in breastfeeding and our analysis suggest that Zoledronic acid anhydrous poses Low risk for infant while breastfeeding and hence Zometa | Zoledronic Acid Injection, Solution, Concentrate itself shall be considered Low risk item for breastfeeding.

Zometa | Zoledronic Acid Injection, Solution, Concentrate Breastfeeding Analsys


Zoledronic acid anhydrous while Breastfeeding

Low Risk

CAS Number: 118072-93-8

It is composed by bisphosphonates. Most bisphosphonates are acidic compounds that achieve low plasma concentration. Both features make it unlikely excretion into the milk in clinically significant amount. Intestinal absorption of bisphosphonates is very low even during fasting and is considered negligible in the presence of milk due to formation with the calcium of non absorbable compounds. Among bisphosponate preparations, Tiludronate and Zoledronate have the longest half-lives period of elimination and thus they are the less indicated to take while breastfeeding. A latest update no published data were found on excretion in the breast milk. Until more data about this drug regarding breastfeeding is available, safer known alternatives (pamidronate) should be of choice, especially in the neonatal period and in case of prematurity.


Zometa | Zoledronic Acid Injection, Solution, Concentrate Breastfeeding Analsys - 2


Zoledronic acid anhydrous while Breastfeeding

CAS Number: 118072-93-8

Because no information is available on the use of zoledronic acid during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. However, absorption of zoledronic acid by a breastfed infant is unlikely.


Zometa | Zoledronic Acid Injection, Solution, Concentrate and breastfeeding

I already used Zometa | Zoledronic Acid Injection, Solution, Concentrate and meanwhile I breastfed my baby should I be concerned?

Zometa | Zoledronic Acid Injection, Solution, Concentrate is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Zometa | Zoledronic Acid Injection, Solution, Concentrate so you should inform him based on your convenience.


My health care provider has asked me to use Zometa | Zoledronic Acid Injection, Solution, Concentrate, what to do?

Zometa | Zoledronic Acid Injection, Solution, Concentrate comes in category of low risk and if your doctor is aware that you are breastfeeding it should be ok to use without much concerns.


If I am using Zometa | Zoledronic Acid Injection, Solution, Concentrate, will my baby need extra monitoring?

Not much monitoring required while using Zometa | Zoledronic Acid Injection, Solution, Concentrate


Who can I talk to if I have questions about usage of Zometa | Zoledronic Acid Injection, Solution, Concentrate in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week