Propylthiouracil | Hikma Pharmaceuticals Usa Inc. Breastfeeding

It is recommended to breastfeed exclusively for six months and then while introducing to other food sources extend it to twelve months. In this duration most mothers will need help of some sort of medication, It could be for short term like could and flue or it could be something chronic like Arthritis or Diabetes and here comes the question of safety of medication in use. In this post we will figure out what is Propylthiouracil | Hikma Pharmaceuticals Usa Inc. and whether its safe to use Propylthiouracil | Hikma Pharmaceuticals Usa Inc. while nursing or not.

What is Propylthiouracil | Hikma Pharmaceuticals Usa Inc. used for?


: Propylthiouracil is indicated: in patients with Graves' disease with hyperthyroidism or toxic multinodular goiter who are intolerant of methimazole and for whom surgery or radioactive iodine therapy is not an appropriate treatment option. to ameliorate symptoms of hyperthyroidism in preparation for thyroidectomy or radioactive iodine therapy in patients who are intolerant of methimazole.

Is using Propylthiouracil | Hikma Pharmaceuticals Usa Inc. unsafe in breastfeeding? Can there be bad consequences for baby if I use it while breastfeeding?

Propylthiouracil | Hikma Pharmaceuticals Usa Inc. safe for breastfeeding
Active ingredient in Propylthiouracil | Hikma Pharmaceuticals Usa Inc. is Propylthiouracil and based on our analysis of Propylthiouracil it appears that using Propylthiouracil | Hikma Pharmaceuticals Usa Inc. is safe in breastfeeding. Below is analysis of Propylthiouracil while breastfeeding.

Propylthiouracil | Hikma Pharmaceuticals Usa Inc. Breastfeeding Analsys


Propylthiouracil while Breastfeeding

Safe

CAS Number: 51-52-5

Small amount of Propylthiouracil can reach the breast milk but it doesn't cause harm to the thyroid function (Low 1979, Kampmann 1980, Cooper 1987). The American Thyroid Association among others (Mandel 2001, Stagnaro 2011, Alexander 2017) stated that a daily dose as high as 450 mg is safe while breastfeeding. However, some studies have shown no harmful effect at a daily dose as high as 750 mg (Kampmann 1980, McDougall 1986, Cooper 1987, Momotani 1989 y 2000, Bartalena 2005, Azizi 2006, Marx 2008, Inoue 2009, Glatstein 2009). Methimazole or Carbimazole is preferred since liver toxicity has been found among patients who were treated with Propylthiouracil (Karras 2009, 2010 y 2012, Azizi 2011, Serrano 2014, Hudzik 2016). The American Academy of Pediatrics has rated it (2001) as compatible with breastfeeding. Eleventh WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.


Propylthiouracil | Hikma Pharmaceuticals Usa Inc. Breastfeeding Analsys - 2


Propylthiouracil while Breastfeeding

CAS Number: 51-52-5

Is Propylthiouracil | Hikma Pharmaceuticals Usa Inc. safe while breastfeeding

Propylthiouracil (PTU) had been considered the antithyroid drug of choice during lactation;[1][2] however, findings that the rates of liver injury higher with PTU than with methimazole has altered this judgement.[3] Some experts now recommend that methimazole should be considered the antithyroid drug of choice in nursing mothers.[4][5] No cases of PTU-induced liver damage have been reported in breastfed infants and it is unknown if the small amounts of the drug in breastmilk can cause liver damage. The drug or breastfeeding should be discontinued if liver toxicity is suspected. Dosages of PTU should be limited to 450 mg daily during breastfeeding.[6] The American Thyroid Association recommends only monitoring infants for appropriate growth and development during routine pediatric health and wellness evaluations and routine assessment of serum thyroid function in the child is not recommended.[6] Rare idiosyncratic reactions (e.g., agranulocytosis) might occur, and the infant should be watched for signs of infection. Monitoring of the infant's complete blood count and differential is advisable if there is a suspicion of a drug-induced blood dyscrasia.



What if I already have used Propylthiouracil | Hikma Pharmaceuticals Usa Inc.?

It is always a good idea to keep your healthcare provider or doctor informed about your drug usage during pregnancy and breastfeeding but if you have not informed your doctor about Propylthiouracil | Hikma Pharmaceuticals Usa Inc. and have used it then do not panic as Propylthiouracil | Hikma Pharmaceuticals Usa Inc. is mostly safe in breastfeeding and should not cause any harm to your baby.


My health care provider has asked me to use Propylthiouracil | Hikma Pharmaceuticals Usa Inc., what to do?

Usage of Propylthiouracil | Hikma Pharmaceuticals Usa Inc. is safe for nursing mothers and baby, No worries.


If I am using Propylthiouracil | Hikma Pharmaceuticals Usa Inc., will my baby need extra monitoring?

No


Who can I talk to if I have questions about usage of Propylthiouracil | Hikma Pharmaceuticals Usa Inc. in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week