Promethazine Hydrochloride And Phenylephrine Hydrochloride | Promethazine And Phenylephrine Solution Breastfeeding

There are high number of clear evidence that breastfeeding provides best nutrition that you can give to your baby. It is also evident that lactation is good for mothers health as well. Evolution has designed breastfeeding in a way that it caters all nutritional need of your child. However modern medicine is quite new for evolution, that is why mothers body is not well prepared to filter unnecessary chemical found in medicines. It becomes a necessity to figure out which drug is safe and which drug is dangerous for your newborn while nursing. In this article we will understand function of Promethazine Hydrochloride And Phenylephrine Hydrochloride | Promethazine And Phenylephrine Solution and its suitability with breastfeeding.

What is Promethazine Hydrochloride And Phenylephrine Hydrochloride | Promethazine And Phenylephrine Solution ?


Promethazine hydrochloride and phenylephrine hydrochloride oral solution, USP is indicated for the temporary relief of upper respiratory symptoms, including nasal congestion, associated with allergy or the common cold.

Promethazine Hydrochloride And Phenylephrine Hydrochloride | Promethazine And Phenylephrine Solution safe in breastfeeding?

Promethazine Hydrochloride And Phenylephrine Hydrochloride | Promethazine And Phenylephrine Solution low risk for breastfeeding
Promethazine hydrochloride and Phenylephrine hydrochloride are the two main ingredients of Promethazine Hydrochloride And Phenylephrine Hydrochloride | Promethazine And Phenylephrine Solution. Based on our individual analysis of Promethazine hydrochloride and Phenylephrine hydrochloride we can safely say that Promethazine Hydrochloride And Phenylephrine Hydrochloride | Promethazine And Phenylephrine Solution has low risk while breastfeeding. Below we have summarized the usage of Promethazine hydrochloride and Phenylephrine hydrochloride while breastfeeding, we recommend you to go through it for better understanding of your usage.

Promethazine Hydrochloride And Phenylephrine Hydrochloride | Promethazine And Phenylephrine Solution Breastfeeding Analsys


Promethazine hydrochloride while Breastfeeding

Low Risk

CAS Number: 60-87-7

1st-generation-antihistamine and phenothiazine-type drug with a strong sedative effect. At latest update relevant published data on excretion into breast milk were not found. It may decrease prolactin levels and interfere with milk production during the first few weeks after birth (Pontiroli 1981, Messinis 1985).Pharmacokinetic data (high volume of distribution and high plasma protein-binding capacity) would render it unlikely a significant passage into the breastmilk.In addition, a low oral bioavailability would hinder a further passage to infant’s plasma through the ingested breastmilk, except on premature infants and immediate neonatal period when there may be an increased intestinal permeability.There are doubts about any association with Sudden Infant Death Syndrome (SIDS) (Kahn 1982, Stanton 1983). It may be considered compatible with breastfeeding on isolated doses such as those used for pre-surgical medication or traveler's dizziness (WHO 2002). Avoid a repeated use as it may cause drowsiness in the infant.Avoid using it in the immediate neonatal period (first 4 to 6 weeks after birth) and in case of prematurity. If used, follow-up the infant for drowsiness and feeding issues. It is not recommended bed-sharing when taking this medication (UNICEF 2006, ABM 2008, Landa 2012, UNICEF 2013).

Phenylephrine hydrochloride while Breastfeeding

Low Risk

CAS Number: 59-42-7

Is Promethazine Hydrochloride And Phenylephrine Hydrochloride | Promethazine And Phenylephrine Solution safe while breastfeeding

Used on topical decongestant solutions for nose drops at low concentration. 10% midriatic eye drops are available. Because low concentration is used on nose and ophtalmic drops a significant excretion into breast milk is unlikely. Low oral biodisponibility minimizes any risk of harmful effect in the infant. Authorized for nasal or ophtalmic use on children aged younger than 1 year. Although on latest update relevant data on breastfeeding was not found it is considered to be safe when minimal dose is used. Avoid excessive or long term use. A related drug Pseudoephedrine can inhibit milk production. It would be advisable to press on the lachrimal sac to minimize absorption.


Promethazine Hydrochloride And Phenylephrine Hydrochloride | Promethazine And Phenylephrine Solution Breastfeeding Analsys - 2


Promethazine hydrochloride while Breastfeeding

CAS Number: 60-87-7

Based on minimal excretion of other phenothiazine derivatives, it appears that occasional short-term use of promethazine for the treatment of nausea and vomiting poses little risk to the breastfed infant. With repeated doses, observe infants for excess sedation. Because promethazine can lower basal prolactin secretion, promethazine might interfere with the establishment of lactation if given during labor, before lactation is well established or with a sympathomimetic such as pseudoephedrine. An antiemetic without potent histamine blocking action is preferred in nursing mothers.

Phenylephrine hydrochloride while Breastfeeding

CAS Number: 59-42-7

The oral bioavailability of phenylephrine is only about 40%,[1] so the drug is unlikely to reach the infant in large amounts. However, intravenous or oral administration of phenylephrine might decrease milk production. Because no information is available on the use of oral phenylephrine during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.Phenylephrine nasal spray or ophthalmic drops are less likely to decrease lactation. To substantially diminish the effect of the drug after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.



What should I do if I am breastfeeding mother and I am already exposed to Promethazine Hydrochloride And Phenylephrine Hydrochloride | Promethazine And Phenylephrine Solution?

Promethazine Hydrochloride And Phenylephrine Hydrochloride | Promethazine And Phenylephrine Solution is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Promethazine Hydrochloride And Phenylephrine Hydrochloride | Promethazine And Phenylephrine Solution so you should inform him based on your convenience.


My doctor has prescribed me Promethazine Hydrochloride And Phenylephrine Hydrochloride | Promethazine And Phenylephrine Solution, what should I do?

Promethazine Hydrochloride And Phenylephrine Hydrochloride | Promethazine And Phenylephrine Solution comes in category of low risk and if your doctor is aware that you are breastfeeding it should be ok to use without much concerns.


If I am using Promethazine Hydrochloride And Phenylephrine Hydrochloride | Promethazine And Phenylephrine Solution, will my baby need extra monitoring?

Not much monitoring required while using Promethazine Hydrochloride And Phenylephrine Hydrochloride | Promethazine And Phenylephrine Solution


Who can I talk to if I have questions about usage of Promethazine Hydrochloride And Phenylephrine Hydrochloride | Promethazine And Phenylephrine Solution in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week