Tranxene T-tab | Clorazepate Dipotassium 0.5 [usp'u] Breastfeeding
Do you know that important immune protective proteins are present in breast milk? Breast milk also contains required vitamins, minerals, saturated and un saturated fats. These things are extremely important for development of healthy brain. If you are taking any medicine for short term or for the chronic reason then that passes in breast milk as well, that is why you should always check the drug with your health care provider. Here at DrLact we try to analyze drugs based on available researches and in this sheet we will present our analysis for Tranxene T-tab | Clorazepate Dipotassium 0.5 [usp'u].

What is Tranxene T-tab | Clorazepate Dipotassium 0.5 [usp'u] used for?


TRANXENE is indicated for the management of anxiety disorders or for the short-term relief of the symptoms of anxiety. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic. TRANXENE tablets are indicated as adjunctive therapy in the management of partial seizures. The effectiveness of TRANXENE tablets in long-term management of anxiety, that is, more than 4 months, has not been assessed by systematic clinical studies. Long-term studies in epileptic patients, however, have shown continued therapeutic activity. The physician should reassess periodically the usefulness of the drug for the individual patient. TRANXENE tablets are indicated for the symptomatic relief of acute alcohol withdrawal.

Is using Tranxene T-tab | Clorazepate Dipotassium 0.5 [usp'u] unsafe in breastfeeding? Can there be bad consequences for baby if I use it while breastfeeding?

Tranxene T-tab | Clorazepate Dipotassium 0.5 [usp'u] low risk for breastfeeding
Tranxene T-tab | Clorazepate Dipotassium 0.5 [usp'u] contains only one active ingredient that is Clorazepate dipotassium. We have analyzed the usage of Clorazepate dipotassium in breastfeeding and our analysis suggest that Clorazepate dipotassium poses Low risk for infant while breastfeeding and hence Tranxene T-tab | Clorazepate Dipotassium 0.5 [usp'u] itself shall be considered Low risk item for breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
Usage during Lactation TRANXENE tablets should not be given to nursing mothers since it has been reported that nordiazepam is excreted in human breast milk.

Tranxene T-tab | Clorazepate Dipotassium 0.5 [usp'u] Breastfeeding Analsys


Clorazepate dipotassium while Breastfeeding

Low Risk

CAS Number: 57109-90-7

Long-acting benzodiazepine. Most of the clorazepate is metabolized to N-desmethyldiazepam (nordiazepam) which is the active metabolite of diazepam. It is excreted in breast milk in clinically insignificant amounts (Rey 1979). Sedation has been observed in infants whose mothers were taking diazepam (Wesson 1985). Due to the lack of publications on this subject, until more information is known about this drug in relation to breastfeeding, safer known alternatives are preferred, especially in the neonatal period and in case of prematurity (McElhatton 1994). Occasional and low-dose use of benzodiazepines is compatible with breastfeeding. It is advisable to choose short-duration benzodiazepines and to use the minimum effective dose. Monitor drowsiness and the adequate feeding of the infant (Kanto 1982). It is not recommended to co-sleep with the baby if you are taking this medication (UNICEF 2013, Landa 2012, ABM 2008, UNICEF 2006).


Tranxene T-tab | Clorazepate Dipotassium 0.5 [usp'u] Breastfeeding Analsys - 2


Clorazepate dipotassium while Breastfeeding

CAS Number: 57109-90-7

Clorazepate is excreted into breastmilk and appears to accumulate in the serum of breastfed infants. Because the half-life of clorazepate and its active metabolite are long, timing breastfeeding with respect to the dose is of little or no benefit in reducing infant exposure. Other agents may be preferred, especially while nursing a newborn or preterm infant.


Tranxene T-tab | Clorazepate Dipotassium 0.5 [usp'u] and breastfeeding

I already used Tranxene T-tab | Clorazepate Dipotassium 0.5 [usp'u] and meanwhile I breastfed my baby should I be concerned?

Tranxene T-tab | Clorazepate Dipotassium 0.5 [usp'u] is in the category of low risk, if you have already used it then its not a big deal if health and behavior of baby is good. However your health care provider shall be aware of the fact that you have used Tranxene T-tab | Clorazepate Dipotassium 0.5 [usp'u] so you should inform him based on your convenience.


My health care provider has asked me to use Tranxene T-tab | Clorazepate Dipotassium 0.5 [usp'u], what to do?

Tranxene T-tab | Clorazepate Dipotassium 0.5 [usp'u] comes in category of low risk and if your doctor is aware that you are breastfeeding it should be ok to use without much concerns.


If I am using Tranxene T-tab | Clorazepate Dipotassium 0.5 [usp'u], will my baby need extra monitoring?

Not much monitoring required while using Tranxene T-tab | Clorazepate Dipotassium 0.5 [usp'u]


Who can I talk to if I have questions about usage of Tranxene T-tab | Clorazepate Dipotassium 0.5 [usp'u] in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week