Pliaglis | Lidocaine And Tetracaine Cream while Breastfeeding
American Academy of Pediatrics and other medical experts exclusively recommend to breastfeed the baby for first 6 months. Once you introduce baby to other foods it is recommended to breastfeed for at least first year of babys life. Taking medication while breastfeeding could be tricky as most drugs pass in breast milk. In this article we will evaluate Pliaglis | Lidocaine And Tetracaine Cream for its safety in breastfeeding.

What is Pliaglis | Lidocaine And Tetracaine Cream used for?


PLIAGLIS Cream is a combination of lidocaine, an amide local anesthetic, and tetracaine, an ester local anesthetic, and is indicated for use on intact skin in adults to provide topical local analgesia for superficial dermatological procedures such as dermal filler injection, pulsed dye laser therapy, facial laser resurfacing, and laser-assisted tattoo removal. PLIAGLIS Cream is a combination of lidocaine, an amide local anesthetic, and tetracaine, an ester local anesthetic, indicated for use on intact skin in adults to provide topical local analgesia for superficial dermatological procedures such as dermal filler injection, pulsed dye laser therapy, facial laser resurfacing, and laser-assisted tattoo removal.

What are the risk associated with Pliaglis | Lidocaine And Tetracaine Cream usage while breastfeeding? What precautions shall I take while using it in breastfeeding?

Pliaglis | Lidocaine And Tetracaine Cream safe for breastfeeding
Pliaglis | Lidocaine And Tetracaine Cream is primarily made of two things Lidocaine, Tetracaine. What we have done here is we have analyzed Lidocaine for its impact on breastfeeding and analyzed Tetracaine for its impact on breastfeeding. Our analysis of Lidocaine and Tetracaine suggests that Pliaglis | Lidocaine And Tetracaine Cream is probably safe in breastfeeding however we suggest you to check detail about both below.

Statement of Manufacturer/Labeler about breastfeeding usage
8.3 Nursing Mothers Lidocaine is excreted into human milk and it is not known if tetracaine is excreted into human milk. Therefore, caution should be exercised when PLIAGLIS Cream is administered to a nursing mother since the milk:plasma ratio of lidocaine is 0.4 and is not determined for tetracaine. In a prior report, when lidocaine was used as an epidural anesthetic for cesarean section in 27 women, a milk:plasma ratio of 1.07 ±0.82 was found by using AUC values. Following single dose administration of 20 mg of lidocaine for a dental procedure, the point value milk:plasma ratio was similarly reported as 1.1 at five to six hours after injection. Thus, the estimated maximum total daily dose of lidocaine delivered to the infant via breast milk would be approximately 36 mcg/kg. Based on these data and the low concentrations of lidocaine and tetracaine found in the plasma after topical administration of PLIAGLIS Cream in recommended doses, the small amount of these primary compounds and their metabolites that would be ingested orally by a suckling infant is unlikely to cause adverse effects [see Clinical Pharmacology (12.3)].

Pliaglis | Lidocaine And Tetracaine Cream Breastfeeding Analsys


Lidocaine while Breastfeeding

Safe

CAS Number: 137-58-6

Compatible with breastfeeding no matter the multiple ways it can be used: anesthetic, anti-arrhythmic, or anti-epileptic drug. Excreted into breast milk in non-significant amount with no side effects on breastfed infants from treated mothers. As a topical anesthetic (dermatologic, dental-stomatologic, ophtalmotologic and otologic preparations) it has an almost nil systemic absorption. Avoid using it on the nipple, but if necessary do it after the breast feed, wipe it out and rinse with water before the next feed, An euptectic mixture with added Prilocaine (EMLA) is used for dermatologic anesthesia. There is an increased risk of Methemoglobinemia when applied on large surfaces or taken by mouth. Intrapartum anesthesia may delay the onset of phase II of Lactogenesis or milk coming-in. The American Academy of Pediatrics rates it usually compatible with Breastfeeding.

Tetracaine while Breastfeeding

Safe

CAS Number: 94-24-6

Anesthetic drugs for topical use, both dermatological and odontological, have almost nil absorption when properly used. Do not apply on breast. Otherwise, do it after having nursed, and cleanse it thoroughly with water before next feeding.


Pliaglis | Lidocaine And Tetracaine Cream Breastfeeding Analsys - 2


Lidocaine while Breastfeeding

CAS Number: 137-58-6

Pliaglis | Lidocaine And Tetracaine Cream and breastfeeding

Lidocaine concentrations in milk during continuous IV infusion, epidural administration and in high doses as a local anesthetic are low and the lidocaine is poorly absorbed by the infant. Lidocaine is not expected to cause any adverse effects in breastfed infants. No special precautions are required.[1][2][3] Lidocaine labor and delivery with other anesthetics and analgesics has been reported by some to interfere with breastfeeding. However, this assessment is controversial and complex because of the many different combinations of drugs, dosages and patient populations studied as well as the variety of techniques used and deficient design of many of the studies. Overall it appears that with good breastfeeding support epidural lidocaine with or without fentanyl or one of its derivatives has little or no adverse effect on breastfeeding success.[4][5][6][7][8] Labor pain medication may delay the onset of lactation.

Tetracaine while Breastfeeding

CAS Number: 94-24-6

No information is available on the use of tetracaine during breastfeeding. Based on the low excretion of other local anesthetics into breastmilk, a single dose of injected tetracaine during breastfeeding, such as for a dental procedure, is unlikely to adversely affect the breastfed infant. However, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. Topical application of tetracaine to the mother is unlikely to affect her breastfed infant if it is applied away from the breast. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[1]


Is Pliaglis | Lidocaine And Tetracaine Cream safe while breastfeeding

I already used Pliaglis | Lidocaine And Tetracaine Cream and meanwhile I breastfed my baby should I be concerned?

It is always a good idea to keep your healthcare provider or doctor informed about your drug usage during pregnancy and breastfeeding but if you have not informed your doctor about Pliaglis | Lidocaine And Tetracaine Cream and have used it then do not panic as Pliaglis | Lidocaine And Tetracaine Cream is mostly safe in breastfeeding and should not cause any harm to your baby.


My health care provider has asked me to use Pliaglis | Lidocaine And Tetracaine Cream, what to do?

Definitely, Pliaglis | Lidocaine And Tetracaine Cream is safe in lactation for baby. No wonder your doctor has recommended it.


If I am using Pliaglis | Lidocaine And Tetracaine Cream, will my baby need extra monitoring?

No extra baby monitoring required while mother is using Pliaglis | Lidocaine And Tetracaine Cream


Who can I talk to if I have questions about usage of Pliaglis | Lidocaine And Tetracaine Cream in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week