Bosentan Bosentan Anhydrous 0.64 Mg Breastfeeding

Modern medicine has evolved so much so that sooner or later every breastfeeding mother needs to take it in one form or other. Medication that is present in mothers blood will transfer into her breast milk to some extent. Most drugs do so at low levels and pose no real risk to infants but then there are some exceptions. In This post will discuss whether Bosentan Bosentan Anhydrous 0.64 Mg is safe in breast-feeding or not.

What is Bosentan Bosentan Anhydrous 0.64 Mg used for?


Bosentan is indicated for the treatment of pulmonary arterial hypertension (PAH) (WHO Group 1): •in adults to improve exercise ability and to decrease clinical worsening. Studies establishing effectiveness included predominantly patients with WHO Functional Class II-IV symptoms and etiologies of idiopathic or heritable PAH (60%), PAH associated with connective tissue diseases (21%), and PAH associated with congenital heart disease with left-to-right shunts (18%) [see Clinical Studies (14.1)]. Bosentan is an endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension (PAH) (WHO Group 1): •in adults to improve exercise ability and to decrease clinical worsening. Studies establishing effectiveness included predominantly patients with WHO Functional Class II-IV symptoms and etiologies of idiopathic or heritable PAH (60%), PAH associated with connective tissue diseases (21%), and PAH associated with congenital heart disease with left-to-right shunts (18%) (1).

Bosentan Bosentan Anhydrous 0.64 Mg while breastfeeding safe or not? Can there be any side effects for infant while using it during breastfeeding?

Bosentan Bosentan Anhydrous 0.64 Mg low risk for breastfeeding
Bosentan anhydrous is the one and only active ingredient present in Bosentan Bosentan Anhydrous 0.64 Mg. Bosentan anhydrous in itself is a low risk drug for lactation so it is easy to understand that Bosentan Bosentan Anhydrous 0.64 Mg also comes in category of Low Risk item while breastfeeding. Below is the summary of Bosentan anhydrous in breastfeeding.

Bosentan Bosentan Anhydrous 0.64 Mg Breastfeeding Analsys


Bosentan anhydrous while Breastfeeding

Low Risk

CAS Number: 147536-97-8

Indicated for the treatment of pulmonary arterial hypertension. Pharmacokinetic data (moderately high molecular weight and high percentage of protein binding capacity) make it unlikely a milk passage in significant amounts.Low oral bioavailability hinders its passage from the ingested milk to infant's plasma, except in preterm and immediate neonatal period that may show an increased intestinal permeability. Although no samples have been taken to analyze the concentration in breast milk, a 30 weeks old premature infant who was breastfed for 2-and-a-half months, while his mother was treated with Bosentan and Sildenafil, did not present side-effects. It is approved for Pediatric use from 1-year-old or 10 kg to higher, but there are not published data on neonatal indication. It would be preferred a safer alternative until more data is available about this drug regarding breastfeeding, especially during the neonatal period and in case of prematurity.


Bosentan Bosentan Anhydrous 0.64 Mg Breastfeeding Analsys - 2


Bosentan anhydrous while Breastfeeding

CAS Number: 147536-97-8

There is little published experience with bosentan during breastfeeding. An alternate drug may be preferred, especially while nursing a newborn or preterm infant.


Is Bosentan Bosentan Anhydrous 0.64 Mg safe while breastfeeding

I am nursing mother and I have already used Bosentan Bosentan Anhydrous 0.64 Mg, what should I do?

During whole lactation period you shall first discuss with your doctor and then together you shall decide whether you shall take that drug or not however if you have already taken Bosentan Bosentan Anhydrous 0.64 Mg then you shall inform your doctor, But you should not be worried too much as Bosentan Bosentan Anhydrous 0.64 Mg comes in category of low risk drug.


I am nursing mother and my doctor has suggested me to use Bosentan Bosentan Anhydrous 0.64 Mg, is it safe?

Though Bosentan Bosentan Anhydrous 0.64 Mg dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.


If I am using Bosentan Bosentan Anhydrous 0.64 Mg, will my baby need extra monitoring?

Not much


Who can I talk to if I have questions about usage of Bosentan Bosentan Anhydrous 0.64 Mg in breastfeeding?

US
National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

UK
National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

Australia
National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Canada
Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week