Phenergan | Promethazine Hydrochloride 25 Mg while Breastfeeding
Modern medicine has evolved so much so that sooner or later every breastfeeding mother needs to take it in one form or other. Medication that is present in mothers blood will transfer into her breast milk to some extent. Most drugs do so at low levels and pose no real risk to infants but then there are some exceptions. In This post will discuss whether Phenergan | Promethazine Hydrochloride 25 Mg is safe in breast-feeding or not.

What is Phenergan | Promethazine Hydrochloride 25 Mg used for?

PHENERGAN Injection is indicated for the following conditions: Amelioration of allergic reactions to blood or plasma. In anaphylaxis as an adjunct to epinephrine and other standard measures after the acute symptoms have been controlled. For other uncomplicated allergic conditions of the immediate type when oral therapy is impossible or contraindicated. For sedation and relief of apprehension and to produce light sleep from which the patient can be easily aroused. Active treatment of motion sickness. Prevention and control of nausea and vomiting associated with certain types of anesthesia and surgery. As an adjunct to analgesics for the control of postoperative pain. Preoperative, postoperative, and obstetric (during labor) sedation. Intravenously in special surgical situations, such as repeated bronchoscopy, ophthalmic surgery, and poor-risk patients, with reduced amounts of meperidine or other narcotic analgesic as an adjunct to anesthesia and analgesia.

I am currently breastfeeding and I want to know if using Phenergan | Promethazine Hydrochloride 25 Mg is safe for my kid? Does it have any effect on milk production?

Phenergan | Promethazine Hydrochloride 25 Mg low risk for breastfeeding
Promethazine hydrochloride is the one and only active ingredient present in Phenergan | Promethazine Hydrochloride 25 Mg. Promethazine hydrochloride in itself is a low risk drug for lactation so it is easy to understand that Phenergan | Promethazine Hydrochloride 25 Mg also comes in category of Low Risk item while breastfeeding. Below is the summary of Promethazine hydrochloride in breastfeeding.

Statement of Manufacturer/Labeler about breastfeeding usage
Nursing Mothers It is not known whether PHENERGAN Injection is excreted in human milk. Because many drugs are excreted in human milk, and because of the potential for serious adverse reactions in nursing infants from PHENERGAN Injection, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

Phenergan | Promethazine Hydrochloride 25 Mg Breastfeeding Analsys

Promethazine hydrochloride while Breastfeeding

Low Risk

CAS Number: 60-87-7

1st-generation-antihistamine and phenothiazine-type drug with a strong sedative effect. At latest update relevant published data on excretion into breast milk were not found. It may decrease prolactin levels and interfere with milk production during the first few weeks after birth (Pontiroli 1981, Messinis 1985).Pharmacokinetic data (high volume of distribution and high plasma protein-binding capacity) would render it unlikely a significant passage into the breastmilk.In addition, a low oral bioavailability would hinder a further passage to infant’s plasma through the ingested breastmilk, except on premature infants and immediate neonatal period when there may be an increased intestinal permeability.There are doubts about any association with Sudden Infant Death Syndrome (SIDS) (Kahn 1982, Stanton 1983). It may be considered compatible with breastfeeding on isolated doses such as those used for pre-surgical medication or traveler's dizziness (WHO 2002). Avoid a repeated use as it may cause drowsiness in the infant.Avoid using it in the immediate neonatal period (first 4 to 6 weeks after birth) and in case of prematurity. If used, follow-up the infant for drowsiness and feeding issues. It is not recommended bed-sharing when taking this medication (UNICEF 2006, ABM 2008, Landa 2012, UNICEF 2013).

Phenergan | Promethazine Hydrochloride 25 Mg Breastfeeding Analsys - 2

Promethazine hydrochloride while Breastfeeding

CAS Number: 60-87-7

Is Phenergan | Promethazine Hydrochloride 25 Mg safe while breastfeeding

Based on minimal excretion of other phenothiazine derivatives, it appears that occasional short-term use of promethazine for the treatment of nausea and vomiting poses little risk to the breastfed infant. With repeated doses, observe infants for excess sedation. Because promethazine can lower basal prolactin secretion, promethazine might interfere with the establishment of lactation if given during labor, before lactation is well established or with a sympathomimetic such as pseudoephedrine. An antiemetic without potent histamine blocking action is preferred in nursing mothers.

Phenergan | Promethazine Hydrochloride 25 Mg safe for breastfeeding

I am nursing mother and I have already used Phenergan | Promethazine Hydrochloride 25 Mg, what should I do?

During whole lactation period you shall first discuss with your doctor and then together you shall decide whether you shall take that drug or not however if you have already taken Phenergan | Promethazine Hydrochloride 25 Mg then you shall inform your doctor, But you should not be worried too much as Phenergan | Promethazine Hydrochloride 25 Mg comes in category of low risk drug.

My health care provider has asked me to use Phenergan | Promethazine Hydrochloride 25 Mg, what to do?

Though Phenergan | Promethazine Hydrochloride 25 Mg dose not comes in category of safe drugs rather it comes in category of low risk but if your doctor is aware that you are breastfeeding your baby and has still recommended it then its advantages must be outweighing the risks.

If I am using Phenergan | Promethazine Hydrochloride 25 Mg, will my baby need extra monitoring?

Not much

Who can I talk to if I have questions about usage of Phenergan | Promethazine Hydrochloride 25 Mg in breastfeeding?

National Womens Health and Breastfeeding Helpline: 800-994-9662 (TDD 888-220-5446) 9 a.m. and 6 p.m. ET, Monday through Friday

National Breastfeeding Helpline: 0300-100-0212 9.30am to 9.30pm, daily
Association of Breastfeeding Mothers: 0300-330-5453
La Leche League: 0345-120-2918
The Breastfeeding Network supporter line in Bengali and Sylheti: 0300-456-2421
National Childbirth Trust (NCT): 0300-330-0700

National Breastfeeding Helpline: 1800-686-268 24 hours a day, 7 days a week

Telehealth Ontario for breastfeeding: 1-866-797-0000 24 hours a day, 7 days a week