CAS Number: 1314-13-2
It is used topically as an astringent and skin protector, very often together with small amounts of Ferric Oxide to form Calamine (see specific info). It is a product compatible with breastfeeding according to WHO Essential Medicine‚Äôs List - 2002.It is also used in dental hygiene products and cosmetics. Widely used for skin protection of the diaper area in infants. Because of the small dose used and poor absorption into plasma of most topical dermatological preparations, excretion into breastmilk in significant amount appears to be unlikely. Do not apply on the breast to prevent infant ingestion; otherwise, wash it off thoroughly with water before the next breast feed.
Octinoxate (Octylmethoxycinnamate) has been detected in human urine, blood and breast milk and is known for moderate risk of skin allergy. Some studies suggest that Octinoxate has estrogen like effects however less than 1% skin penetration has been found in human laboratory studies. As not much study has been done on effects of Octinoxate during breast feeding its recommended to use safe alternatives.
Octyl Methoxycinnamate (OMC) is a frequently used UV-filter in sunscreens and other cosmetics. Octinoxate can be systemically absorbed after skin application, being found in the deeper layers of the stratum corneum as well as urine, plasma, and breast milk. The mean maximum plasma concentration detected after application of 2mg/cm2 sunscreen was 7ng/mL in women and 16ng/mL in men. FDA study found blood levels 13 times above cutoff for systemic exposure.
Several studies indicated that OMC acts as an endocrine disruptor due to the ability to interfere with endocrine system at different levels. In humans OMC exposure has minor, but statistically significant effects on the levels of testosterone and estradiol. Moreover, some studies suggested that OMC can interact with the hypothalamo-pituitary-thyroid (HPT) axis.
Moreover, a study of offspring of dams treated with OMC (500Ė1000 mg/kg/day) showed sex-dependent behavioral changes, namely decreased motor activity in females, but not in males, and improved spatial learning in males, suggesting that OMC can affect neuronal development, however the doses used in these experiments were extremely high, not relevant to possible human exposure.Note: Study and data for tropical use only
Octyl salicylate is an oil soluble chemical sunscreen agent that absorbs UVB radiation. It does not protect against UVA. Octyl salicylate is used to augment the UVB protection in a sunscreen. Salicylates are weak UVB absorbers and they are generally used in combination with other UV filters
Octisalate rarely causes allergies in tropical usage. Not much study has been done on effects of topical usage of Octisalate during breast feeding however it is known to penetrate the skin hence itís better to use other alternatives.
FDA study found blood levels 10 times above cutoff for systemic exposure, skin penetration in lab studies has been observedNote: Study and data for tropical use only
We have already established that Sunshield Spf-30 | Octinoxate, Octisalate, Zinc Oxide Cream is unsafe in breastfeeding and breastfeeding while using Sunshield Spf-30 | Octinoxate, Octisalate, Zinc Oxide Cream is not a good idea however if have already used
If your doctor knows that you are breastfeeding mother and still prescribes Sunshield Spf-30 | Octinoxate, Octisalate, Zinc Oxide Cream then there must be good reason for that as Sunshield Spf-30 | Octinoxate, Octisalate, Zinc Oxide Cream is considered unsafe, It usually happens when doctor finds that overall advantage of taking
Yes, Extra monitoring is required if mother is using Sunshield Spf-30 | Octinoxate, Octisalate, Zinc Oxide Cream and breastfeeding as it is considered unsafe for baby.
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