Question

I am a breastfeeding mother and i want to know if it is safe to use Doxycycline? Is Doxycycline safe for nursing mother and child? Does Doxycycline extracts into breast milk? Does Doxycycline has any long term or short term side effects on infants? Can Doxycycline influence milk supply or can Doxycycline decrease milk supply in lactating mothers?

Doxycycline lactation summary

Doxycycline usage has low risk in breastfeeding
  • DrLact safety Score for Doxycycline is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Doxycycline may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Doxycycline may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Doxycycline low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Doxycycline We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Doxycycline usage in lactation

Excreted into breast milk in quantities that would be clinically significant, however, intestinal absorption by infant's gut is hampered because of formation of chelating products by union with the milk's calcium. Tetracycline is at lesser amount excreted into breast milk and at higher proportion bound to calcium, hence, it is fewer absorbed than Doxycycline. Thus, it is a optimal alternative while breastfeeding. Long-term treatments are not recommended (over 3-4 weeks) since it may cause damage of the growth cartilage, teeth discoloration and imbalance of intestinal flora. Be aware of false negative results that may be obtained from infants with bacterial cultures when the mother is on antibiotics.

Answer by DrLact: About Doxycycline usage in lactation

A number of reviews have stated that tetracyclines are contraindicated during breastfeeding because of possible staining of infants' dental enamel or bone deposition of tetracyclines. However, a close examination of available literature indicates that there is not likely to be harm in short-term use of doxycycline during lactation because milk levels are low and absorption by the infant is inhibited by the calcium in breastmilk. Short-term use of doxycycline is acceptable in nursing mothers. As a theoretical precaution, avoid prolonged or repeat courses during nursing. Monitor the infant for rash and for possible effects on the gastrointestinal flora, such as diarrhea or candidiasis (thrush, diaper rash).

Alternate Drugs

Aztreonam(Safe)
Didanosine(Unsafe)
Malathion(Low Risk)
Cefprozil(Safe)
Ritonavir(Unsafe)
Methicillin(Low Risk)
Ofloxacin(Safe)
Cefdinir(Safe)
Gatifloxacin(Low Risk)
Dapsone(Low Risk)
Nevirapine(Low Risk)
Naftifine(Safe)
Cefazolin(Safe)
Enoxacin(Low Risk)
Abacavir(Safe)
Cefoxitin(Safe)
Nelfinavir(Unsafe)
Meropenem(Safe)
Capreomycin(Low Risk)
Rifaximin(Safe)
Famciclovir(Low Risk)
Cefotetan(Safe)
Ertapenem(Safe)
Neomycin(Safe)
Doxycycline(Low Risk)
Zidovudine(Low Risk)
Cefaclor(Safe)
Erythromycin(Low Risk)
Indinavir(Unsafe)
Lomefloxacin(Low Risk)
Amikacin(Safe)
Tenofovir(Safe)
Nafcillin(Safe)
Clindamycin(Low Risk)
Amantadine(Low Risk)
Levofloxacin(Low Risk)
Valganciclovir(Low Risk)
Econazole(Safe)
Kanamycin(Safe)
Moxifloxacin(Low Risk)
Ganciclovir(Low Risk)
Demeclocycline(Low Risk)
Cefixime(Safe)
Acyclovir(Safe)
Primaquine(Low Risk)
Lindane(Unsafe)
Saquinavir(Unsafe)
Quinine(Safe)
Atovaquone(Low Risk)
Cefepime(Safe)
Linezolid(Low Risk)
Efavirenz(Unsafe)
Methicillin(Low Risk)
Ofloxacin(Safe)
Cefdinir(Safe)
Gatifloxacin(Low Risk)
Methenamine(Unsafe)
Cefazolin(Safe)
Enoxacin(Low Risk)
Cefoxitin(Safe)
Capreomycin(Low Risk)
Mupirocin(Safe)
Cefotetan(Safe)
Ertapenem(Safe)
Neomycin(Safe)
Doxycycline(Low Risk)
Cefaclor(Safe)
Erythromycin(Low Risk)
Lomefloxacin(Low Risk)
Nalidixic Acid(Low Risk)
Iodine(Unsafe)
Nafcillin(Safe)
Clindamycin(Low Risk)
Levofloxacin(Low Risk)
Amikacin(Safe)
Moxifloxacin(Low Risk)
Demeclocycline(Low Risk)
Cefixime(Safe)
Kanamycin(Safe)
Cefepime(Safe)
Aztreonam(Safe)
Cefprozil(Safe)
Doxycycline(Low Risk)
Demeclocycline(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.