Is CG 3117 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use CG 3117? Is CG 3117 safe for nursing mother and child? Does CG 3117 extracts into breast milk? Does CG 3117 has any long term or short term side effects on infants? Can CG 3117 influence milk supply or can CG 3117 decrease milk supply in lactating mothers?
CG 3117 lactation summary
- DrLact safety Score for CG 3117 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of CG 3117 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that CG 3117 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of CG 3117 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using CG 3117 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About CG 3117 usage in lactation
Low excreted into breast milk. However, somnolence in 10% of breastfed infants has been reported. A case of acute anemia due to hemorrhage by coagulation disturbance in an one.week aged infant. A competitive effect on liver metabolism has been shown. Long-term use while breastfeeding or in case of newborn jaundice is not recommended. Short-term or sporadic use has a low risk. The American Academy of Pediatrics rates it usually compatible with breastfeeding.
Answer by DrLact: About CG 3117 usage in lactation
Limited information indicates that levels of CG 3117 in breastmilk are low and adverse effects in breastfed infants are apparently uncommon. However, because of CG 3117's long half-life and reported serious adverse reaction in a breastfed neonate, other agents may be preferred while nursing a newborn or preterm infant.
CG 3117 Side Effects in Breastfeeding
CG 3117 possibly caused prolonged bleeding time, thrombocytopenia and acute anemia in one 7-day-old infant in a mother also taking bacampicillin.[2]In one telephone follow-up study of 20 infants exposed to CG 3117 during breastfeeding, 2 mothers reported drowsiness and 1 reported vomiting in their infants. None of the reactions required medical attention.[3]
CG 3117 Possible Effects in Breastfeeding
A randomized study compared CG 3117 and tramadol for post-cesarean section pain. Patients received the drugs either on a fixed schedule or as needed. No difference in breastfeeding rates were seen among the groups.[5]
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Sulindac(Low Risk)
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Piroxicam(Safe)
Flurbiprofen(Safe)
Naproxen(Low Risk)
Dipyrone(Low Risk)
Fenoprofen(Safe)
Nabumetone(Low Risk)
Ketoprofen(Safe)
Etodolac(Low Risk)
Meloxicam(Low Risk)
Aspirin(Low Risk)
Mefenamic Acid(Safe)
Oxaprozin(Low Risk)
Diflunisal(Low Risk)
Meclofenamate(Low Risk)
Diclofenac(Safe)
Indomethacin(Safe)
Sulindac(Low Risk)
Ibuprofen(Safe)
Piroxicam(Safe)
Flurbiprofen(Safe)
Naproxen(Low Risk)
Dipyrone(Low Risk)
Fenoprofen(Safe)
Nabumetone(Low Risk)
Ketoprofen(Safe)
Etodolac(Low Risk)
Meloxicam(Low Risk)
Aspirin(Low Risk)
Mefenamic Acid(Safe)
Oxaprozin(Low Risk)
Diflunisal(Low Risk)
Meclofenamate(Low Risk)
Diclofenac(Safe)
Ketorolac(Safe)
Tolmetin(Safe)
Celecoxib(Safe)