Is Basiliximab Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Basiliximab? Is Basiliximab safe for nursing mother and child? Does Basiliximab extracts into breast milk? Does Basiliximab has any long term or short term side effects on infants? Can Basiliximab influence milk supply or can Basiliximab decrease milk supply in lactating mothers?
Basiliximab lactation summary
- DrLact safety Score for Basiliximab is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Basiliximab may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Basiliximab may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Basiliximab low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Basiliximab We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Basiliximab usage in lactation
Used to prevent rejection of transplanted kidney.
Answer by DrLact: About Basiliximab usage in lactation
No information is available on the clinical use of basiliximab during breastfeeding. Because basiliximab is a large protein molecule with a molecular weight of about 144,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, basiliximab should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. The manufacturer recommends that breastfeeding be discontinued during basiliximab therapy.
Alternate Drugs
Cetuximab(Unsafe)
Ranibizumab(Safe)
Omalizumab(Low Risk)
Rituximab(Low Risk)
Ustekinumab(Low Risk)
Bevacizumab(Low Risk)
Natalizumab(Low Risk)
Trastuzumab(Unsafe)
Denosumab(Low Risk)
Certolizumab Pegol(Safe)
Ipilimumab(Unsafe)
Infliximab(Safe)
Abciximab(Low Risk)
Basiliximab(Low Risk)
Belimumab(Low Risk)
Secukinumab(Low Risk)
Brentuximab Vedotin(Low Risk)
Nivolumab(Unsafe)