Is AY 4166 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use AY 4166? Is AY 4166 safe for nursing mother and child? Does AY 4166 extracts into breast milk? Does AY 4166 has any long term or short term side effects on infants? Can AY 4166 influence milk supply or can AY 4166 decrease milk supply in lactating mothers?

• DrLact safety Score for AY 4166 is 5 out of 8 which is considered Unsafe as per our analyses.
• A safety Score of 5 indicates that usage of AY 4166 may cause serious side effects in breastfed baby.
• Our study of different scientific research indicates that AY 4166 may cause moderate to high side effects or may affect milk supply in lactating mother.
• Our suggestion is to use safer alternate options rather than using AY 4166 .
• It is recommended to evaluate the advantage of not breastfeeding while using AY 4166 Vs not using AY 4166 And continue breastfeeding.
• While using AY 4166 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
• Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Meglitinide drugs stimulate secretion of endogen insulin.Oral anti-diabetic drugs are useless for treatment of diabetes type 1. For diabetes type 2, diet and exercise are advisable. Breastfeeding helps to lower glucemia level. See section on Maternal diabetes mellitus

No information is available on the use of AY 4166 during breastfeeding. AY 4166 is a weak acid that is over 98% protein bound, so it is unlikely to pass into breastmilk in clinically important amounts. If AY 4166 is required by the mother, it is not a reason to discontinue breastfeeding. Monitor breastfed infants for signs of hypoglycemia such as jitteriness, excessive sleepiness, poor feeding, seizures cyanosis, apnea, or hypothermia. If there is concern, monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with AY 4166.[1] However, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.