Is Pertuzumab Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Pertuzumab? Is Pertuzumab safe for nursing mother and child? Does Pertuzumab extracts into breast milk? Does Pertuzumab has any long term or short term side effects on infants? Can Pertuzumab influence milk supply or can Pertuzumab decrease milk supply in lactating mothers?
Answer by DrLact: About Pertuzumab usage in lactation
No information is available on the clinical use of pertuzumab during breastfeeding. Because pertuzumab is a large protein molecule with a molecular weight of about 148,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. Until more data become available, pertuzumab should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. The manufacturer recommends that breastfeeding be discontinued during pertuzumab therapy and for 7 months after the last dose.
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