Is Enalapril Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Enalapril? Is Enalapril safe for nursing mother and child? Does Enalapril extracts into breast milk? Does Enalapril has any long term or short term side effects on infants? Can Enalapril influence milk supply or can Enalapril decrease milk supply in lactating mothers?
Enalapril lactation summary
- DrLact safety Score for Enalapril is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Enalapril is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Enalapril does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Enalapril safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Enalapril usage in lactation
Excretion into breast milk is clinically non-significant. No harmful effects among breastfed infants from treated mothers have been found. American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.
Answer by DrLact: About Enalapril usage in lactation
Because of the low levels of enalapril in breastmilk, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants.
Enalapril Side Effects in Breastfeeding
None reported in 4 breastfed infants whose mothers were taking oral enalapril 5 to 10 mg daily.[1][2]
Enalapril Possible Effects in Breastfeeding
In 15 postmenopausal hypertensive women (prior lactation status not stated), serum prolactin levels were decreased by 22% compared to placebo after enalapril 20 mg once daily for 15 days.[4] The maternal prolactin level in a mother with established lactation may not affect her ability to breastfeed. A woman with pre-eclampsia was treated was started at term with oral enalapril 10 mg daily. Her milk came in on day 3 postpartum and she had no difficulties with nursing during 5 weeks of observation.[5]
Alternate Drugs
Fosinopril(Low Risk)
Trandolapril(Dangerous)
Enalapril(Safe)
Ramipril(Low Risk)
Lisinopril(Low Risk)
Captopril(Safe)
Benazepril(Safe)
Benazepril(Safe)
Verapamil(Safe)
Timolol(Safe)
Nimodipine(Safe)
Nebivolol(Unsafe)
Amlodipine(Low Risk)
Fosinopril(Low Risk)
Sotalol(Low Risk)
Nifedipine(Safe)
Felodipine(Low Risk)
Propranolol(Safe)
Valsartan(Low Risk)
Trandolapril(Dangerous)
Terazosin(Unsafe)
Torsemide(Low Risk)
Minoxidil(Safe)
Telmisartan(Unsafe)
Spironolactone(Safe)
Enalapril(Safe)
Nadolol(Unsafe)
Prazosin(Unsafe)
Reserpine(Unsafe)
Diltiazem(Safe)
Metoprolol(Safe)
Methyldopa(Safe)
Losartan(Low Risk)
Ramipril(Low Risk)
Chlorthalidone(Dangerous)
Levobunolol(Low Risk)
Irbesartan(Unsafe)
Chlorothiazide(Safe)
Labetalol(Safe)
Lisinopril(Low Risk)
Isradipine(Low Risk)
Eprosartan(Low Risk)
Captopril(Safe)
Carvedilol(Low Risk)
Indapamide(Low Risk)
Doxazosin(Safe)
Bumetanide(Low Risk)
Bisoprolol(Low Risk)
Hydrochlorothiazide(Safe)
Guanfacine(Low Risk)
Bosentan(Low Risk)
Bendroflumethiazide(Unsafe)
Atenolol(Unsafe)
Hydralazine(Safe)
Nitrendipine(Safe)
Acebutolol(Unsafe)
Furosemide(Low Risk)
Nicardipine(Safe)
Nisoldipine(Low Risk)