Is Cemiplimab Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Cemiplimab? Is Cemiplimab safe for nursing mother and child? Does Cemiplimab extracts into breast milk? Does Cemiplimab has any long term or short term side effects on infants? Can Cemiplimab influence milk supply or can Cemiplimab decrease milk supply in lactating mothers?

No information is available on the clinical use of cemiplimab during breastfeeding. Because cemiplimab is a large protein molecule with a molecular weight of about 146,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract. The manufacturer recommends that breastfeeding be discontinued during cemiplimab therapy and for 4 months after the last dose. Cemiplimab is a human immunoglobulin G4 (IgG4) antibody. Holder pasteurization (62.5 degrees C for 30 minutes) decreases the concentration of endogenous immunoglobulin G by up to 79%.[1][2] A study of 67 colostrum samples that underwent Holder pasteurization found that IgG amounts decreased by 34 to 40%. Specific IgG subclasses decreased by different amounts, with Holder pasteurization having little effect on IgG4 activity.[3] None of the studies measured IgG activity.