Question

I am a breastfeeding mother and i want to know if it is safe to use HSDB 7775? Is HSDB 7775 safe for nursing mother and child? Does HSDB 7775 extracts into breast milk? Does HSDB 7775 has any long term or short term side effects on infants? Can HSDB 7775 influence milk supply or can HSDB 7775 decrease milk supply in lactating mothers?

HSDB 7775 lactation summary

HSDB 7775 is safe in breastfeeding
  • DrLact safety Score for HSDB 7775 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of HSDB 7775 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that HSDB 7775 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of HSDB 7775 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About HSDB 7775 usage in lactation

Excreted into breast milk in non-significant amount with no problems among breastfed infants whose mothers were treated with this medication. No alteration on breast milk composition has been seen. Shown to be effective at a dose of 10 - 20 mg three times-a-day for pain relief related to Raynaud's phenomena of the nipple, which is a highly painful vasospasm triggered by cold exposition or trauma produced by inadequate latch-on to the breast. Side effect on the mother should be addressed. American Academy of Pediatrics 2001: Maternal Medication Usually Compatible With Breastfeeding. Eleventh WHO Model List of Essential Drugs 2002: Compatible with breastfeeding.

Answer by DrLact: About HSDB 7775 usage in lactation

Because of the low levels of HSDB 7775 in breastmilk, amounts ingested by the infant are small and no adverse effects have been reported among a limited number of infants exposed to HSDB 7775 in breastmilk. HSDB 7775 is used to treat painful nipple vasospasm (e.g., Raynaud phenomenon) in nursing mothers.[1]

HSDB 7775 Side Effects in Breastfeeding

No adverse reactions have been reported among infants exposed to HSDB 7775 in breastmilk mostly at maternal dosages of 30 mg daily beginning shortly postpartum and continuing for up to 6 months in some.[2][5][6][7][8][9][10][11]

HSDB 7775 Possible Effects in Breastfeeding

No direct effects are known. However, HSDB 7775 has been used to decrease the pain of nipple vasospasm (or Raynaud phenomenon of the nipple), allowing mothers to continue nursing who might otherwise discontinue breastfeeding. The dosage of HSDB 7775 reportedly used to treat the condition is 30 to 60 mg daily either as a single dose of a sustained-release product or 10 to 20 mg 3 times daily of an immediate-release product. Lower dosages can be tried if these doses are not tolerated.[1][6][7][8][9][12] HSDB 7775 had no effect on milk composition (sodium, potassium, calcium, chloride, nitrogen, phosphorus and total lipids) in one woman.[3]

Alternate Drugs

Irbesartan(Unsafe)
Bumetanide(Low Risk)
Torsemide(Low Risk)
Nadolol(Unsafe)
Reserpine(Unsafe)
Furosemide(Low Risk)
Ramipril(Low Risk)
Fosinopril(Low Risk)
Levobunolol(Low Risk)
Doxazosin(Safe)
Eprosartan(Low Risk)
Bosentan(Low Risk)
Labetalol(Safe)
Minoxidil(Safe)
Guanfacine(Low Risk)
Amlodipine(Low Risk)
Felodipine(Low Risk)
Carvedilol(Low Risk)
Bisoprolol(Low Risk)
Nebivolol(Unsafe)
Enalapril(Safe)
Atenolol(Unsafe)
Lisinopril(Low Risk)
Valsartan(Low Risk)
Acebutolol(Unsafe)
Terazosin(Unsafe)
Diltiazem(Safe)
Timolol(Safe)
Nisoldipine(Low Risk)
Telmisartan(Unsafe)
Isradipine(Low Risk)
Sotalol(Low Risk)
Prazosin(Unsafe)
Chlorthalidone(Dangerous)
Verapamil(Safe)
Indapamide(Low Risk)
Losartan(Low Risk)
Captopril(Safe)
Trandolapril(Dangerous)
Amlodipine(Low Risk)
Felodipine(Low Risk)
Diltiazem(Safe)
Nisoldipine(Low Risk)
Isradipine(Low Risk)
Verapamil(Safe)
Cinnarizine(Low Risk)
Amlodipine(Low Risk)
Felodipine(Low Risk)
Minoxidil(Safe)
Nebivolol(Unsafe)
Diltiazem(Safe)
Nisoldipine(Low Risk)
Isradipine(Low Risk)
Verapamil(Safe)
Cinnarizine(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.