Is BRN 0498823 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use BRN 0498823? Is BRN 0498823 safe for nursing mother and child? Does BRN 0498823 extracts into breast milk? Does BRN 0498823 has any long term or short term side effects on infants? Can BRN 0498823 influence milk supply or can BRN 0498823 decrease milk supply in lactating mothers?
BRN 0498823 lactation summary
- DrLact safety Score for BRN 0498823 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of BRN 0498823 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that BRN 0498823 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of BRN 0498823 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About BRN 0498823 usage in lactation
It is excreted into breast milk in clinically non-significant amount possibly due to its high plasma protein binding capacity. Evidence on other antihypertensive drugs of the same family with similar structure, pharmacokinetics and action profile (nifedipine, nimodipine, nicardipine) has shown that they are excreted into milk in non-significant amount. Until more extensive published data about this drug regarding breastfeeding are available a safer alternative drug should be used, especially during the neonatal period and/or in case of premature infants.
Answer by DrLact: About BRN 0498823 usage in lactation
Based on limited data, it is unlikely that BRN 0498823 will reach the infant in clinically important amounts. However, it may be preferable to use another agent drug for which more safety information is available.
Alternate Drugs
Isradipine(Low Risk)
Sotalol(Low Risk)
Nisoldipine(Low Risk)
Telmisartan(Unsafe)
Chlorthalidone(Dangerous)
Verapamil(Safe)
Indapamide(Low Risk)
Propranolol(Safe)
Prazosin(Unsafe)
Chlorothiazide(Safe)
Trandolapril(Dangerous)
Hydrochlorothiazide(Safe)
Nimodipine(Safe)
Losartan(Low Risk)
Captopril(Safe)
Torsemide(Low Risk)
Nadolol(Unsafe)
Irbesartan(Unsafe)
Bumetanide(Low Risk)
Spironolactone(Safe)
Hydralazine(Safe)
Metoprolol(Safe)
Reserpine(Unsafe)
Furosemide(Low Risk)
Nifedipine(Safe)
Bendroflumethiazide(Unsafe)
Ramipril(Low Risk)
Fosinopril(Low Risk)
Levobunolol(Low Risk)
Doxazosin(Safe)
Eprosartan(Low Risk)
Benazepril(Safe)
Bosentan(Low Risk)
Labetalol(Safe)
Minoxidil(Safe)
Guanfacine(Low Risk)
Felodipine(Low Risk)
Carvedilol(Low Risk)
Amlodipine(Low Risk)
Bisoprolol(Low Risk)
Methyldopa(Safe)
Nebivolol(Unsafe)
Enalapril(Safe)
Atenolol(Unsafe)
Lisinopril(Low Risk)
Nitrendipine(Safe)
Valsartan(Low Risk)
Acebutolol(Unsafe)
Nicardipine(Safe)
Diltiazem(Safe)
Timolol(Safe)
Terazosin(Unsafe)
Verapamil(Safe)
Cinnarizine(Low Risk)
Nimodipine(Safe)
Nifedipine(Safe)
Felodipine(Low Risk)
Amlodipine(Low Risk)
Nitrendipine(Safe)
Nicardipine(Safe)
Diltiazem(Safe)
Isradipine(Low Risk)
Nisoldipine(Low Risk)
Cinnarizine(Low Risk)
Nimodipine(Safe)
Hydralazine(Safe)
Nifedipine(Safe)
Felodipine(Low Risk)
Minoxidil(Safe)
Amlodipine(Low Risk)
Sildenafil(Safe)
Nitroglycerin(Safe)
Nebivolol(Unsafe)
Nitrendipine(Safe)
Nicardipine(Safe)
Diltiazem(Safe)
Isradipine(Low Risk)
Nisoldipine(Low Risk)
Verapamil(Safe)