Is EINECS 254-513-1 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use EINECS 254-513-1? Is EINECS 254-513-1 safe for nursing mother and child? Does EINECS 254-513-1 extracts into breast milk? Does EINECS 254-513-1 has any long term or short term side effects on infants? Can EINECS 254-513-1 influence milk supply or can EINECS 254-513-1 decrease milk supply in lactating mothers?
EINECS 254-513-1 lactation summary
- DrLact safety Score for EINECS 254-513-1 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of EINECS 254-513-1 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that EINECS 254-513-1 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of EINECS 254-513-1 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About EINECS 254-513-1 usage in lactation
It is excreted into breast milk in clinically non-significant amount possibly due to its high plasma protein binding capacity. Evidence on other antihypertensive drugs of the same family with similar structure, pharmacokinetics and action profile (nifedipine, nimodipine, nicardipine) has shown that they are excreted into milk in non-significant amount. Until more extensive published data about this drug regarding breastfeeding are available a safer alternative drug should be used, especially during the neonatal period and/or in case of premature infants.
Answer by DrLact: About EINECS 254-513-1 usage in lactation
Based on limited data, it is unlikely that EINECS 254-513-1 will reach the infant in clinically important amounts. However, it may be preferable to use another agent drug for which more safety information is available.
Alternate Drugs
Bosentan(Low Risk)
Labetalol(Safe)
Minoxidil(Safe)
Guanfacine(Low Risk)
Amlodipine(Low Risk)
Felodipine(Low Risk)
Carvedilol(Low Risk)
Bisoprolol(Low Risk)
Methyldopa(Safe)
Nebivolol(Unsafe)
Enalapril(Safe)
Nitrendipine(Safe)
Atenolol(Unsafe)
Lisinopril(Low Risk)
Valsartan(Low Risk)
Acebutolol(Unsafe)
Nicardipine(Safe)
Terazosin(Unsafe)
Diltiazem(Safe)
Timolol(Safe)
Nisoldipine(Low Risk)
Telmisartan(Unsafe)
Isradipine(Low Risk)
Sotalol(Low Risk)
Prazosin(Unsafe)
Chlorthalidone(Dangerous)
Verapamil(Safe)
Indapamide(Low Risk)
Propranolol(Safe)
Chlorothiazide(Safe)
Nimodipine(Safe)
Losartan(Low Risk)
Captopril(Safe)
Trandolapril(Dangerous)
Hydrochlorothiazide(Safe)
Irbesartan(Unsafe)
Bumetanide(Low Risk)
Torsemide(Low Risk)
Nadolol(Unsafe)
Spironolactone(Safe)
Hydralazine(Safe)
Metoprolol(Safe)
Bendroflumethiazide(Unsafe)
Reserpine(Unsafe)
Furosemide(Low Risk)
Nifedipine(Safe)
Doxazosin(Safe)
Eprosartan(Low Risk)
Benazepril(Safe)
Ramipril(Low Risk)
Fosinopril(Low Risk)
Levobunolol(Low Risk)
Amlodipine(Low Risk)
Felodipine(Low Risk)
Nitrendipine(Safe)
Nicardipine(Safe)
Diltiazem(Safe)
Nisoldipine(Low Risk)
Isradipine(Low Risk)
Verapamil(Safe)
Nimodipine(Safe)
Cinnarizine(Low Risk)
Nifedipine(Safe)
Amlodipine(Low Risk)
Felodipine(Low Risk)
Minoxidil(Safe)
Sildenafil(Safe)
Nitroglycerin(Safe)
Nitrendipine(Safe)
Nebivolol(Unsafe)
Nicardipine(Safe)
Diltiazem(Safe)
Nisoldipine(Low Risk)
Isradipine(Low Risk)
Verapamil(Safe)
Nimodipine(Safe)
Cinnarizine(Low Risk)
Hydralazine(Safe)
Nifedipine(Safe)