Question

I am a breastfeeding mother and i want to know if it is safe to use Dornase Alfa? Is Dornase Alfa safe for nursing mother and child? Does Dornase Alfa extracts into breast milk? Does Dornase Alfa has any long term or short term side effects on infants? Can Dornase Alfa influence milk supply or can Dornase Alfa decrease milk supply in lactating mothers?

Dornase Alfa lactation summary

Dornase Alfa is safe in breastfeeding
  • DrLact safety Score for Dornase Alfa is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Dornase Alfa is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Dornase Alfa does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Dornase Alfa safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Dornase Alfa usage in lactation

We are working on a comment for this product.

Answer by DrLact: About Dornase Alfa usage in lactation

No information is available on the clinical use of dornase alpha (hamster) during breastfeeding. Because it is a large protein molecule with a molecular weight of about 37,000, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant's gastrointestinal tract.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.