Is Canagliflozin Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Canagliflozin? Is Canagliflozin safe for nursing mother and child? Does Canagliflozin extracts into breast milk? Does Canagliflozin has any long term or short term side effects on infants? Can Canagliflozin influence milk supply or can Canagliflozin decrease milk supply in lactating mothers?
Answer by DrLact: About Canagliflozin usage in lactation
No information is available on the clinical use of canagliflozin during breastfeeding. Canagliflozin is is an uncharged molecule that is 99% protein bound in plasma, so it is unlikely to pass into breastmilk in clinically important amounts. The manufacturer does not recommend canagliflozin during breastfeeding because of a theoretical risk to the infant's developing kidney. An alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Alternate Drugs
Colesevelam(Safe)
Miglitol(Safe)
Tolbutamide(Safe)
Rosiglitazone(Low Risk)
Empagliflozin(Unsafe)
Repaglinide(Unsafe)
Pioglitazone(Low Risk)
Nateglinide(Unsafe)
Dapagliflozin(Unsafe)
Metformin(Safe)
Alogliptin(Low Risk)
Insulin(Safe)
Glyburide(Safe)
Dulaglutide(Low Risk)
Glipizide(Safe)
Glimepiride(Unsafe)
Linagliptin(Low Risk)
Liraglutide(Low Risk)
Chlorpropamide(Low Risk)
Sitagliptin(Low Risk)
Acetohexamide(Low Risk)
Saxagliptin(Low Risk)
Acarbose(Safe)
Empagliflozin(Unsafe)
Dapagliflozin(Unsafe)
Empagliflozin(Unsafe)
Dapagliflozin(Unsafe)