Question

I am a breastfeeding mother and i want to know if it is safe to use Iron Dextran? Is Iron Dextran safe for nursing mother and child? Does Iron Dextran extracts into breast milk? Does Iron Dextran has any long term or short term side effects on infants? Can Iron Dextran influence milk supply or can Iron Dextran decrease milk supply in lactating mothers?

Iron Dextran lactation summary

Iron Dextran is safe in breastfeeding
  • DrLact safety Score for Iron Dextran is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Iron Dextran is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Iron Dextran does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Iron Dextran safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Iron Dextran usage in lactation

Hydroxide complex formed by iron dextran for parenteral administration.In addition to its high molecular weight, other characteristics of iron metabolism in the body make unlikely that it would be excreted in a significant amount into breast milk.It is a medication used for treatment of Neonatal Anemia in premature babies. Iron is excreted in small amounts in human milk, usually being enough for covering the daily needs of infants due to its high bioavailability. There is no correlation between mother's daily intake of iron and its concentration in breast milk.Iron supplementation to the mother does not increase levels of iron in breast milk or infant plasma significantly. Excessive supplementation can reduce the zinc concentration in milk. WHO List of Essential Medicines 2002: compatible with breastfeeding.

Answer by DrLact: About Iron Dextran usage in lactation

Limited data indicate that trace amounts of iron dextran are excreted into breastmilk. No information is available on the clinical use of iron dextran during breastfeeding. However, intravenous iron dextran has been used in preterm infants for anemia of prematurity and would not be expected to cause any adverse effects in breastfed infants. An alternate intravenous drug with more published data available may be preferred. Pasteurization of milk by the Holder method reduces the concentration of iron in milk by about 6.5%.[1]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.